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Matti Narkia

Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures a... - 0 views

www.bmj.com/...469

2003 March BMJ study research clinical_trial rct elderly old older humans vitamin_D supplementation oral fractures fracture prevention mortality nutrition medline four monthly

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  • Matti Narkia on 05 Oct 09
     
    Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. Trivedi DP, Doll R, Khaw KT. BMJ. 2003 Mar 1;326(7387):469. PMID: 12609940 Conclusion: Four monthly supplementation with 100 000 IU oral vitamin D may prevent fractures without adverse effects in men and women living in the general community.
Matti Narkia

Dietary Mono- and Polyunsaturated Fatty Acids Similarly Affect LDL Size in Healthy Men ... - 0 views

jn.nutrition.org/...715

2002 April JN study research clinical_trial rct humans healthy MUFA PUFA LDL particle size dietary unsaturated fat saturated SFA nutrition LDL_size small_LDL_particles particle_size small CVD medline sdLDL small_LDL

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  • Matti Narkia on 08 Oct 09
     
    Dietary mono- and polyunsaturated fatty acids similarly affect LDL size in healthy men and women. Kratz M, Gülbahçe E, von Eckardstein A, Cullen P, Cignarella A, Assmann G, Wahrburg U. J Nutr. 2002 Apr;132(4):715-8. PMID: 11925466 In conclusion, our data indicate that dietary unsaturated fat similarly reduces LDL size relative to saturated fat. However, the small magnitude of this reduction also suggests that the composition of dietary fat is not a major factor affecting LDL size.
Matti Narkia

The Serum LDL/HDL Cholesterol Ratio Is Influenced More Favorably by Exchangin... - 1 views

jn.nutrition.org/...78

2003 January JN study research clinical_trial rct humans women LDL_HDL ratio LDL HDL apolipoprotein_A-I apolipoprotein_B coconut_oil lauric_acid myristic_acid SFA nutrition saturated fat saturated_fat unsaturated unsaturated_fat PUFA MUFA medline CVD

shared by Matti Narkia on 07 Oct 09 - Cached
  • Matti Narkia on 07 Oct 09
     
    The serum LDL/HDL cholesterol ratio is influenced more favorably by exchanging saturated with unsaturated fat than by reducing saturated fat in the diet of women. Müller H, Lindman AS, Brantsaeter AL, Pedersen JI. J Nutr. 2003 Jan;133(1):78-83. PMID: 12514271 We conclude that, to influence the LDL/HDL cholesterol ratio, changing the proportions of dietary fatty acids may be more important than restricting the percentage of total or saturated fat energy, at least when derived mainly from lauric and myristic acids, both of which increase HDL cholesterol.
Matti Narkia

Plasma Vitamin D and 25OHD Responses of Young and Old Men to Supplementation with Vitam... - 0 views

www.jacn.org/...357

2002 August jacn study research clinical_trial rct men young elderly old older healthy humans vitamin_D 25ohd vitamin_D3 supplementation nutrition Dawson-Hughes Harris responses response absorption aging medline age

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  • Matti Narkia on 05 Oct 09
     
    Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3. Harris SS, Dawson-Hughes B. J Am Coll Nutr. 2002 Aug;21(4):357-62. PMID: 12166534 Conclusions: There appears to be no age-related impairment among men in the absorption or metabolism of 20 µg/day of vitamin D3 taken orally for at least eight weeks.
Matti Narkia

Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after ... - 0 views

www.journals.elsevierhealth.com/...abstract

2009 November Bone study research clinical_trial rct humans patients hip fracture hip_fracture vitamin_D insufficiency deficiency vitamin_D2 vitamin_D3 supplementation 25ohd nutrition fractures PTH medline serum

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  • Matti Narkia on 05 Oct 09
     
    Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol. Glendenning P, Chew GT, Seymour HM, Gillett MJ, Goldswain PR, Inderjeeth CA, Vasikaran SD, Taranto M, Musk AA, Fraser WD. Bone. 2009 Nov;45(5):870-5. Epub 2009 Jul 23. PMID: 19631774 doi:10.1016/j.bone.2009.07.015 Cholecalciferol supplementation resulted in a 31% greater increase in total HPLC-measured 25OHD (p=0.010) and 52% greater rise in RIA-measured 25OHD (p0.05). In vitamin D-insufficient hip fracture patients, supplementation with cholecalciferol 1000 IU/day for three months was more effective in increasing serum 25OHD than an equivalent dose of ergocalciferol. However, the lack of difference in PTH lowering between calciferol treatments raises questions about the biological importance of this observation.
Matti Narkia

Effects of daily ingestion of chilli on serum lipoprotein oxidation in adult men and women - 0 views

journals.cambridge.org/...displayFulltext

2006 August study research clinicalt_trial rct humans chili chilli lipoproteins oxidation lipoprotein LDL capsaicin antioxidants nutrition medline diet LDL_oxidation oxLDL CVD prevention Ahuja

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  • Matti Narkia on 12 Oct 09
     
    Effects of daily ingestion of chilli on serum lipoprotein oxidation in adult men and women. Ahuja KD, Ball MJ. Br J Nutr. 2006 Aug;96(2):239-42. PMID: 16923216 In conclusion, regular consumption of chilli for 4 weeks increases the resistance of serum lipoproteins to oxidation.
Matti Narkia

Effects of chili consumption on postprandial glucose, insulin, and energy metabolism --... - 0 views

www.ajcn.org/...63

2006 July ajcn study research clinical_trial rct humans nutrition medline chili chilli consumption postprandial glucose insulin resistance obesity hyperinsulinemia energy expenditure Ahuja

shared by Matti Narkia on 12 Oct 09 - Cached
  • Matti Narkia on 12 Oct 09
     
    Effects of chili consumption on postprandial glucose, insulin, and energy metabolism. Ahuja KD, Robertson IK, Geraghty DP, Ball MJ. Am J Clin Nutr. 2006 Jul;84(1):63-9. PMID: 16825682
Matti Narkia

A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in i... - 0 views

www.springerlink.com/...h7628r66r0552222

2007 September Diabetologia study research clinical_trial rct humans paleolithic diet paleolithic_diet Mediterranean Mediterranean_diet comparison glucose tolerance glucose_tolerance type_2 diabetes intolerance evolution nutition CVD CHD IHD medline

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  • Matti Narkia on 19 Nov 09
     
    A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Lindeberg S, Jönsson T, Granfeldt Y, Borgstrand E, Soffman J, Sjöström K, Ahrén B. Diabetologia. 2007 Sep;50(9):1795-807. Epub 2007 Jun 22. PMID: 17583796 DOI: 10.1007/s00125-007-0716-y Conclusions/interpretation A Palaeolithic diet may improve glucose tolerance independently of decreased waist circumference.
Matti Narkia

Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated... - 0 views

www.jstage.jst.go.jp/..._pdf

2009 July study research clinical_trial rct JELIS Japan humans omega-3 EPA CVD CHD secondary prevention secondary_prevention nutrition medline supplementation patients statin-treated statin statins

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  • Matti Narkia on 18 Nov 09
     
    Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease. Matsuzaki M, Yokoyama M, Saito Y, Origasa H, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K, Matsuzawa Y; JELIS Investigators. Circ J. 2009 Jul;73(7):1283-90. Epub 2009 May 8. PMID: 19423946 Conclusions: EPA is effective for secondary prevention of CAD, especially in individuals with prior MI, and should be added to conventional treatment.
Matti Narkia

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic pati... - 0 views

www.thelancet.com/...abstract

2007 March Lancet study research clinical_trial rct JELIS humans omega-3 EPA Japan nutrition medline CVD CHD prevention major coronary events hypercholesterolemic patients

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  • Matti Narkia on 18 Nov 09
     
    Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; Japan EPA lipid intervention study (JELIS) Investigators. Lancet. 2007 Mar 31;369(9567):1090-8. Erratum in: Lancet. 2007 Jul 21;370(9583):220. PMID: 17398308 doi:10.1016/S0140-6736(07)60527-3 Interpretation EPA is a promising treatment for prevention of major coronary events, and especially non-fatal coronary events, in Japanese hypercholesterolaemic patients
Matti Narkia

JAMA -- Abstract: Omega-3 Augmentation of Sertraline in Treatment of Depression in Pati... - 0 views

jama.ama-assn.org/...1651

2009 October JAMA study research clinical_trial rct humans patients depression CHD CVD sertraline Zoloft Lustral omega-3 augmentation supplementation nutrition medline anti-depressant EPA DHA E-EPA BDI-II BDI HAM-D major

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  • Matti Narkia on 16 Nov 09
     
    Omega-3 augmentation of sertraline in treatment of depression in patients with coronary heart disease: a randomized controlled trial. Carney RM, Freedland KE, Rubin EH, Rich MW, Steinmeyer BC, Harris WS. JAMA. 2009 Oct 21;302(15):1651-7. PMID: 19843899 Conclusions Treatment of patients with CHD and major depression with sertraline and omega-3 fatty acids did not result in superior depression outcomes at 10 weeks, compared with sertraline and placebo. Whether higher doses of omega-3 or sertraline, a different ratio of EPA to DHA, longer treatment, or omega-3 monotherapy can improve depression in patients with CHD remains to be determined
Matti Narkia

Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: systematic rev... - 0 views

www.ajcn.org/...1308

2006 December ajcn study systematic review meta-analysis clinical_trials rcts humans omega-3 PUFA PUFAs nutrition medline depression depressed mood

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  • Matti Narkia on 16 Nov 09
     
    Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: systematic review of published trials. Appleton KM, Hayward RC, Gunnell D, Peters TJ, Rogers PJ, Kessler D, Ness AR. Am J Clin Nutr. 2006 Dec;84(6):1308-16. Review. PMID: 17158410 Conclusions: Trial evidence that examines the effects of n-3 PUFAs on depressed mood is limited and is difficult to summarize and evaluate because of considerable heterogeneity. The evidence available provides little support for the use of n-3 PUFAs to improve depressed mood. Larger trials with adequate power to detect clinically important benefits are required.
Matti Narkia

Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial in... - 0 views

www.springerlink.com/...u3437g0j1877x422

2003 April study research clinical_trial rct humans statin statins acute myocardial infarction myocardial_infarction MI CVD CHD vitamin_E Coenzyme Q10 Coenzyme_Q10 unstable atheroma nutrition medline ubiquinone ubidecarenone coq10

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  • Matti Narkia on 24 Nov 09
     
    Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Singh RB, Neki NS, Kartikey K, Pella D, Kumar A, Niaz MA, Thakur AS. Mol Cell Biochem. 2003 Apr;246(1-2):75-82. PMID: 12841346
Matti Narkia

Long-term vitamin D3 supplementation may have adverse effects on serum lipids during po... - 0 views

www.ncbi.nlm.nih.gov/...9405029

1997 November study research clinical_trial rct humans women long-term vitamin D3 vitamin_D supplementation adverse effects lipids lipid_profile CVD during postmenopausal hormone replacement therapy HRT nutrition LDL risk_factors medline

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  • Matti Narkia on 23 Nov 09
     
    Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy. Heikkinen AM, Tuppurainen MT, Niskanen L, Komulainen M, Penttilä I, Saarikoski S. Eur J Endocrinol. 1997 Nov;137(5):495-502. PMID: 9405029 CONCLUSIONS: Our results confirm the positive long-term effect of HRT with sequential estradiol valerate and cyproterone acetate on serum lipid concentrations. In addition, the results suggest that vitamin D3 supplementation may have unfavorable effects on lipids in postmenopausal women. Pure vitamin D3 treatment was associated with increased serum LDL cholesterol. Furthermore, the beneficial effects of HRT on serum LDL cholesterol content were reduced when estradiol valerate was combined with vitamin D3. However, the relevance of these associations to cardiovascular morbidity remains to be established.
Matti Narkia

Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaque... - 0 views

www.thelancet.com/...fulltext

2003 February Lancet study research clinical_trial rct humans omega-3 fish_oil EPA DHA PUFA CVD CHD atherosclerotic plaques plaque nutrition stability stable inflammation anti-inflammatory carotid

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  • Matti Narkia on 23 Nov 09
     
    Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial. Thies F, Garry JM, Yaqoob P, Rerkasem K, Williams J, Shearman CP, Gallagher PJ, Calder PC, Grimble RF. Lancet. 2003 Feb 8;361(9356):477-85. PMID: 12583947 doi:10.1016/S0140-6736(03)12468-3 Interpretation Atherosclerotic plaques readily incorporate n-3 PUFAs from fish-oil supplementation, inducing changes that can enhance stability of atherosclerotic plaques. By contrast, increased consumption of n-6 PUFAs does not affect carotid plaque fatty-acid composition or stability over the time course studied here. Stability of plaques could explain reductions in non-fatal and fatal cardiovascular events associated with increased n-3 PUFA intake
Matti Narkia

Effects of a Mediterranean-Style Diet on the Need for Antihyperglycemic Drug Therapy in... - 0 views

www.annals.org/...306.short

2009 September annals study research clinical_trial rct humans overweight patients diabetic Mediterranean-style Mediterranen diet Mediterranen_diet low-fat low-fat_diet type_2 diabetes nutrition glycemic_control CVD CHD risk_fatctors nutrtion medline

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  • Matti Narkia on 22 Nov 09
     
    Effects of a Mediterranean-style diet on the need for antihyperglycemic drug therapy in patients with newly diagnosed type 2 diabetes: a randomized trial. Esposito K, Maiorino MI, Ciotola M, Di Palo C, Scognamiglio P, Gicchino M, Petrizzo M, Saccomanno F, Beneduce F, Ceriello A, Giugliano D. Ann Intern Med. 2009 Sep 1;151(5):306-14. Erratum in: Ann Intern Med. 2009 Oct 20;151(8):591. PMID: 19721018 Conclusion: Compared with a low-fat diet, a low-carbohydrate, Mediterranean-style diet led to more favorable changes in glycemic control and coronary risk factors and delayed the need for antihyperglycemic drug therapy in overweight patients with newly diagnosed type 2 diabetes.
Matti Narkia

One-Year Comparison of a High-Monounsaturated Fat Diet With a High-Carbohydrate Diet in... - 0 views

care.diabetesjournals.org/...215.long

2009 February study research clinical:trial rct humans patients diabetic High-Monounsaturated Fat Diet High-Monounsaturated_Fat high MUFA high_MUFA high_MUFA_diet high-carbohydrate high-carbohydrate_diet type_2 diabetes nutrition CVD medline

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  • Matti Narkia on 22 Nov 09
     
    One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes. Brehm BJ, Lattin BL, Summer SS, Boback JA, Gilchrist GM, Jandacek RJ, D'Alessio DA. Diabetes Care. 2009 Feb;32(2):215-20. Epub 2008 Oct 28. PMID: 18957534 doi: 10.2337/dc08-0687 CONCLUSIONS-In individuals with type 2 diabetes, high-MUFA diets are an alternative to conventional lower-fat, high-CHO diets with comparable beneficial effects on body weight, body composition, cardiovascular risk factors, and glycemic control.
Matti Narkia

JAMA -- Influence of a Diet Very High in Vegetables, Fruit, and Fiber and Low in Fat on... - 0 views

jama.ama-assn.org/...289

2007 July JAMA study clinical_trial rct humans women breast cancer breast_cancer diet nutrition secondary prevention secondary_prevention very high vegetables fruit fiber low-fat low-fat_diet prognosis recurrence medline

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  • Matti Narkia on 21 Nov 09
     
    Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial. Pierce JP, Natarajan L, Caan BJ, Parker BA, Greenberg ER, Flatt SW, Rock CL, Kealey S, Al-Delaimy WK, Bardwell WA, Carlson RW, Emond JA, Faerber S, Gold EB, Hajek RA, Hollenbach K, Jones LA, Karanja N, Madlensky L, Marshall J, Newman VA, Ritenbaugh C, Thomson CA, Wasserman L, Stefanick ML. JAMA. 2007 Jul 18;298(3):289-98. PMID: 17635889 Conclusion Among survivors of early stage breast cancer, adoption of a diet that was very high in vegetables, fruit, and fiber and low in fat did not reduce additional breast cancer events or mortality during a 7.3-year follow-up period.
Matti Narkia

Can lifestyle changes reverse coronary heart disease? : The Lancet - 0 views

www.thelancet.com/...abstract

1990 July Lancet study research clinical_trial rct humans Ornish lifestyle changes reverse CVD CHD treatment nutrition regressed low-fat diet low-fat_diet vegetarian vegetarian_diet regression atherosclerosis exercise training smoking stress medline

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  • Matti Narkia on 20 Nov 09
     
    Can lifestyle changes reverse coronary heart disease? The Lifestyle Heart Trial. Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, McLanahan SM, Kirkeeide RL, Brand RJ, Gould KL. Lancet. 1990 Jul 21;336(8708):129-33. PMID: 1973470
Matti Narkia

Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia... - 0 views

springerlink.metapress.com/...m0gfeb9k7tde9jbk

2004 June Diabetologia study researc clinical_trial rct humans abdominally obese men obesity CLA trans-10_cis-12 supplementation adiponectin hyperproinsulinemia insulin_resistance insulin_secretion nutrition proinsulin insulin resistance medline

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  • Matti Narkia on 25 Nov 09
     
    Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: close association with impaired insulin sensitivity. Risérus U, Vessby B, Arner P, Zethelius B. Diabetologia. 2004 Jun;47(6):1016-9. Epub 2004 May 28. PMID: 15168020 DOI: 10.1007/s00125-004-1421-8 Conclusions/interpretation In obese men, t10c12CLA induces hyperproinsulinaemia that is related to impaired insulin sensitivity, independently of changes in insulin concentrations. These results are of clinical interest, as hyperproinsulinaemia predicts diabetes and cardiovascular disease. The use of weight-loss supplements containing this fatty acid is worrying.
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