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Matti Narkia

Study Suggests Coenzyme Q10 Slows Functional Decline in Parkinson's Disease: National I... - 1 views

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    "Results of the first placebo-controlled, multicenter clinical trial of the compound coenzyme Q10 suggest that it can slow disease progression in patients with early-stage Parkinson's disease (PD). While the results must be confirmed in a larger study, they provide hope that this compound may ultimately provide a new way of treating PD.

    The phase II study, led by Clifford Shults, M.D., of the University of California, San Diego (UCSD) School of Medicine, looked at a total of 80 PD patients at 10 centers across the country to determine if coenzyme Q10 is safe and if it can slow the rate of functional decline. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS) and appears in the October 15, 2002, issue of the Archives of Neurology"
Matti Narkia

Coenzyme Q10 - September 15, 2005 - American Family Physician - 0 views

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    Coenzyme Q10.
    Bonakdar RA, Guarneri E.
    Am Fam Physician. 2005 Sep 15;72(6):1065-70. Review.
    PMID: 16190504

    Coenzyme Q10 is a vitamin-like substance used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders such as Parkinson's disease and certain encephalomyopathies for which coenzyme Q10 has gained orphan drug status. Results in other areas of research, including treatment of congestive heart failure and diabetes, appear to be contradictory or need further clarification before proceeding with recommendations. Coenzyme Q10 appears to be a safe supplement with minimal side effects and low drug interaction potential.
Matti Narkia

Coenzyme Q10 - umm.edu - 0 views

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    "Coenzyme Q10 (CoQ10) is a compound found naturally in the energy-producing center of the cell known as the mitochondria. CoQ10 is involved in the making of an important molecule known as adenosine triphosphate (ATP). ATP serves as the cell's major energy source and drives a number of biological processes including muscle contraction and the production of protein. CoQ10 also works as an antioxidant."
Matti Narkia

Coenzyme Q10 - Wikipedia, the free encyclopedia - 0 views

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    "Coenzyme Q10 (also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ10 - pronounced like "ko-cue-ten" -, CoQ, Q10, or simply Q) is a 1,4-benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the isoprenyl chemical subunits.

    This oil-soluble vitamin-like substance is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body's energy is generated this way.[1][2] Therefore, those o
Matti Narkia

Coenzyme Q10 - MayoClinic.com - 0 views

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    "Coenzyme Q10 (CoQ10) is produced by the human body and is necessary for the basic functioning of cells. CoQ10 levels are reported to decrease with age and to be low in patients with some chronic diseases such as heart conditions, muscular dystrophies, Parkinson's disease, cancer, diabetes, and HIV/AIDS. Some prescription drugs may also lower CoQ10 levels. "
Matti Narkia

Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial in... - 0 views

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    Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction.
    Singh RB, Neki NS, Kartikey K, Pella D, Kumar A, Niaz MA, Thakur AS.
    Mol Cell Biochem. 2003 Apr;246(1-2):75-82.
    PMID: 12841346
Matti Narkia

Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials -... - 0 views

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    Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials.
    Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, Leong JY, Watts GF.
    J Hum Hypertens. 2007 Apr;21(4):297-306. Epub 2007 Feb 8.
    PMID: 17287847

    We conclude that coenzyme Q10 has the potential in hypertensive patients to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by up to 10 mm Hg without significant side effects.
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