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Matti Narkia

Effect of Molecular Forms on Distribution of Docosahexaenoic Acid into Organs in Mice - 0 views

www.jstage.jst.go.jp/..._pdf

Docosahexaenoic Acid DHA EPA triglyseride TG EE ethyl ester distribution organs fish oil omega-3 nutrition study research science peer-reviewed medline 2003 imported delicious fish_oil

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    Yukihisa TANAKA, Takashi OHKUBO, Nobuo FUKUDA and Hidehiko HIBINO, "Effect of Molecular Forms on Distribution of Docosahexaenoic Acid into Organs in Mice", J. Oleo Sci., Vol. 52, 89-97 (2003) .
Matti Narkia

Polyunsaturated (n-3) Fatty Acids Susceptible to Peroxidation Are Increased in Plasma a... - 0 views

jn.nutrition.org/...3028

Polyunsaturated Fatty Acids PUFA omega-3 lipid Peroxidation lipidperoxidation DHA triglyceride ethyl ester TG EE study nutrition peer-reviewed research science medline imported delicious

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    Song JH, Fujimoto K, Miyazawa T. Polyunsaturated (n-3) fatty acids susceptible to peroxidation are increased in plasma and tissue lipids of rats fed docosahexaenoic acid-containing oils. J Nutr. 2000 Dec;130(12):3028-33. PMID: 11110863 [PubMed - index
Matti Narkia

Higher plasma docosahexaenoic acid is associated with reduced progression of ... - 0 views

www.jlr.org/...2814

nutrition PUFA EPA DHA ALA alpha-linolenic acid angiography coronary artery disease heart CAD CHD epidemiological finland finnish women reduced progression atherosclerosis medline medicine science study research peer-reviewed 2006 imported delicious

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    Erkkila AT, Matthan NR, Herrington DM, Lichtenstein AH. Higher plasma docosahexaenoic acid is associated with reduced progression of coronary atherosclerosis in women with CAD. J Lipid Res. 2006 Dec;47(12):2814-9. Epub 2006 Sep 18. PMID: 16983146 [Pub
Matti Narkia

Arch Neurol -- Abstract: Plasma Phosphatidylcholine Docosahexaenoic Acid Content and Ri... - 0 views

archneur.ama-assn.org/...1545

medicine medical science scientific article study research nutrition peer-reviewed medline omega-3 dementia alzheimer's brain prevention dha imported delicious

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    Plasma Phosphatidylcholine Docosahexaenoic Acid Content and Risk of Dementia and Alzheimer Disease: The Framingham Heart StudyErnst J. Schaefer, Vanina Bongard, Alexa S. Beiser, Stefania Lamon-Fava, Sander J. Robins, Rhoda Au, Katherine L. Tucker, David
Matti Narkia

Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in ... - 0 views

journals.cambridge.org/...displayFulltext

2004 May bjn study research clinical_trial rct humans elderly older old omega-3 DHA omega-6 AA omega-3-eggs eggs egg DHA-enriched DHA-enriched_eggs egg-yolk powder DHGLA DGLA yolk nutrition medline supplementation CVD

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    Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in erythrocytes of elderly patients. Payet M, Esmail MH, Polichetti E, Le Brun G, Adjemout L, Donnarel G, Portugal H, Pieroni G. Br J Nutr. 2004 May;91(5):789-96. PMID: 15137931 doi:10.1079/BJN20041106
Matti Narkia

Anticancer properties of oxidation products of docosahexaenoic acid - [Chem Phys Lipids... - 0 views

www.ncbi.nlm.nih.gov/...18343223

2008 May study review Anticancer properties anti-cancer oxidation products DHA omega-3 cancer nutrition medline lipid lipid_oxidation peroxidation lipid_peroxidation apoptosis isoprostane

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    Anticancer properties of oxidation products of docosahexaenoic acid. Siddiqui RA, Harvey K, Stillwell W. Chem Phys Lipids. 2008 May;153(1):47-56. Epub 2008 Feb 23. Review. PMID: 18343223
Matti Narkia

PPARalpha signaling mediates the synergistic cytotoxicity of clioquinol and docosahexae... - 0 views

www.ncbi.nlm.nih.gov/...19426685

2009 May study research in_vitro PPARalpha clioquinol DHA omega-3 cancer nutrition medline synergy synergistic

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    The combination effects index (CI) analysis confirmed the synergy of clioquinol and clofibrate on inhibiting cancer cell viability. Using inhibitors to block PPARalpha signaling diminished the synergistic cytotoxicity of clioquinol and DHA. These results provide pharmacological evidence that the synergistic anticancer action of clioquinol and DHA is mediated by PPARalpha signaling in human cancer cells. PPARalpha signaling mediates the synergistic cytotoxicity of clioquinol and docosahexaenoic acid in human cancer cells. Tuller ER, Brock AL, Yu H, Lou JR, Benbrook DM, Ding WQ. Biochem Pharmacol. 2009 May 1;77(9):1480-6. Epub 2009 Feb 13. PMID: 19426685
Matti Narkia

Why fish oils may not always be adequate treatments for depression or other inflammator... - 0 views

www.ncbi.nlm.nih.gov/...18063921

2007 December study research clinical_trial ex_vivo humans omega-3 fish_oil EPA DHA omega-6 AA depression immune function immunity IFN-gamma IL-10 IFN-gamma_IL-10 IFN-gamma:IL-10 ratio nutrition medline Th1 TNF-alpha fish oil

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    Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response. Maes M, Mihaylova I, Kubera M, Bosmans E. Neuro Endocrinol Lett. 2007 Dec;28(6):875-80. PMID: 18063921
Matti Narkia

Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and prefe... - 0 views

www.ncbi.nlm.nih.gov/...17927497

2007 study research clinical_trial rct humans patiens advanced lung cancer lung_cancer fish_oil omega-3 EPA DHA celecoxib COX-2 inhibitor CRP body weight body_weight muscle strength muscle_strength appetite fatigue eicosanoids nutrition medline

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    Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Cerchietti LC, Navigante AH, Castro MA. Nutr Cancer. 2007;59(1):14-20. PMID: 17927497
Matti Narkia

Docosahexaenoic acid induces proteasome-dependent degradation of {beta}-catenin, down-r... - 0 views

carcin.oxfordjournals.org/...1202

2007 June Carcinogenesis study research in_vitro DHA omega-3 proteasome-dependen proteasome degradation beta-catenin down-regulation survivin apoptosis colorectal cancer cells colorectal_cancer COX-2 nutrition medline MMP-7 VEGF MMP

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    The present study, thus, raises the possibility that DHA may exert pro-apoptotic and antitumoral effects through proteasomal regulation of beta-catenin levels and alterations in the expression of TCF-beta-catenin target genes. Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, Monego G, Ranelletti FO, Palozza P. Carcinogenesis. 2007 Jun;28(6):1202-9. Epub 2006 Dec 20. PMID: 17183061 doi:10.1093/carcin/bgl254
Matti Narkia

Modulation of gene expression in eicosapentaenoic acid and docosahexaenoic acid treated... - 0 views

www.pubmedcentral.nih.gov/articlerender.fcgi

2009 March pubmedcentral study research in_vitro cDNA array omega-3 EPA DHA colon adenoma cells colon_adenoma cancer colon_cancer gene expression gene_expression genes nutrition medline modulation

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    DHA and EPA generally modulated different sets of genes, although a few common effects were noted. In our approach, we used preneoplastic adenoma cells which are a relevant model for target cells of chemoprevention. If verified with real time PCR, these results identify genes and targets for chemoprevention of colon cancer. Modulation of gene expression in eicosapentaenoic acid and docosahexaenoic acid treated human colon adenoma cells. Habermann N, Lund EK, Pool-Zobel BL, Glei M. Genes Nutr. 2009 Mar;4(1):73-6. Epub 2009 Feb 21. PMID: 19234733 doi: 10.1007/s12263-009-0112-y.
Matti Narkia

Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth c... - 0 views

www3.interscience.wiley.com/...abstract

1998 December study research in_vitro DHA omega-3 PLA2 phospholipase_A2 activity reduction neuroprotective nutrition medline

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    Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells. Martin RE. J Neurosci Res. 1998 Dec 15;54(6):805-13. PMID: 9856864 DOI: 10.1002/(SICI)1097-4547(19981215)54:63.0.CO;2-4
Matti Narkia

Chemopreventive and renal protective effects for docosahexaenoic acid (DHA): implicatio... - 0 views

www.celldiv.com/...abstract

2009 April study research in_vivo animal_study omega-3 DHA chemopreventive cancer chemotherapy cisplatin synergy anti-cancer CRP lipid_peroxidation malondialdehyde MDA nephrotoxicity kidneys leukocytosis inflammation anti-inflammatory nutrition medline

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    Chemopreventive and renal protective effects for docosahexaenoic acid (DHA): implications of CRP and lipid peroxides. Elmesery ME, Algayyar MM, Salem HA, Darweish MM, El-Mowafy AM. Cell Div. 2009 Apr 2;4(1):6. [Epub ahead of print] PMID: 19341447 doi:10.1186/1747-1028-4-6
Matti Narkia

Antioxidative and anti-inflammatory actions of docosahexaenoic acid and eicosapentaeno... - 0 views

www.liebertonline.com/...jmf.2006.092

2007 June study research in_vitro omega-3 EPA DHA COX-2 XOD antioxidative_enzymes antioxidative enzymes antioxidants PGE2 nitrite thromboxane B2 thromboxane_B2 anti-inflammatory nutrition medline ROS

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    Antioxidative and anti-inflammatory actions of docosahexaenoic acid and eicosapentaenoic acid in renal epithelial cells and macrophages. Kim YJ, Chung HY. J Med Food. 2007 Jun;10(2):225-31. PMID: 17651056 doi:10.1089/jmf.2006.092.
Matti Narkia

Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis ... - 0 views

www.sciencedirect.com/science

2007 January study research in_vitro omega-3 DHA resolvin D1 resolvi_ protectin_D1 protectin resolvins protectins anti-inflammatory lipid mediators lipid_mediators analysis nutrition medline

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    Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms. Hong S, Lu Y, Yang R, Gotlinger KH, Petasis NA, Serhan CN. J Am Soc Mass Spectrom. 2007 Jan;18(1):128-44. Epub 2006 Oct 19. PMID: 17055291 doi:10.1016/j.jasms.2006.09.002    
Matti Narkia

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimula... - 0 views

www.jnutbio.com/...abstract

2007 April study research in_vitro omega-3 DHA EPA macrophages cytokines NF-KappaB TNF-alpha IL-6 IL-1beta nutrition medline mRNA expression anti-inflammatory

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    Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid. Weldon SM, Mullen AC, Loscher CE, Hurley LA, Roche HM. J Nutr Biochem. 2007 Apr;18(4):250-8. Epub 2006 Jun 16. PMID: 16781858 doi:10.1016/j.jnutbio.2006.04.003
Matti Narkia

Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte functio... - 0 views

www.journals.elsevierhealth.com/...abstract

2006 December study research clinical_trial humans men fish oil fish_oil DHA EPA DHA-rich EPA-rich omega-3 phagocytic activity phagocytosis chemotaxis lymphocytes phagocytes gene expression genes immune function immunity nutrition medline

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    Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte function. Gorjão R, Verlengia R, Lima TM, Soriano FG, Boaventura MF, Kanunfre CC, Peres CM, Sampaio SC, Otton R, Folador A, Martins EF, Curi TC, Portiolli EP, Newsholme P, Curi R. Clin Nutr. 2006 Dec;25(6):923-38. Epub 2006 May 11. PMID: 16697494 doi:10.1016/j.clnu.2006.03.004
Matti Narkia

Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell compo... - 0 views

www.ajcn.org/...674

2004 April ajcn study research clinical_trial rct humans healthy omega-3 EPA DHA supplementation fish_oil immunity immune function inflammation lymphocytes monocytes PUFAs PUFA nutrition medline CD69

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    Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans. Kew S, Mesa MD, Tricon S, Buckley R, Minihane AM, Yaqoob P. Am J Clin Nutr. 2004 Apr;79(4):674-81. PMID: 15051614
Matti Narkia

Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human... - 0 views

www.wjgnet.com/...1079.asp

2009 March study research in_vitro omega-3 DHA anti-proliferative growth-inhibitory omega-6 AA ARA colon cancer colon_cancer PUFA PUFAs PGE2 COX-2 expression COX-2_expression down-regulation growth apoptosis nutrition medline omega-6:omega-3 ratio AA:DHA

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    Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells. Habbel P, Weylandt KH, Lichopoj K, Nowak J, Purschke M, Wang JD, He CW, Baumgart DC, Kang JX. World J Gastroenterol. 2009 Mar 7;15(9):1079-84. PMID: 19266600 doi: 10.3748/wjg.15.1079.
Matti Narkia

Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or d... - 0 views

www.sciencedirect.com/science

1997 October study clinical_trial humans men hemostatic factors platelet aggregation platelet_aggregation fish-enriched diet fish fish_oil fish oil DHA omega-3 supplementation nutrition medline CVD

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    Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. Agren JJ, Väisänen S, Hänninen O, Muller AD, Hornstra G. Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):419-21. PMID: 9430389 doi:10.1016/S0952-3278(97)90421-X    
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