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fitspresso

https://www.fitspresso-co.com/ - 0 views

www.fitspresso-co.com

fitspresso fit spresso us uk buy usa 2023 pros 2022 2024 pills order price weight loss espresso fitespresso review amazon tablet reviews customer supplement does it work

shared by fitspresso on 27 Sep 23 - No Cached
  • fitspresso on 27 Sep 23
     
    FitSpresso™ | Official Site fitspresso-co.com FitSpresso Only $39/Bottle Limited Time Offer! FitSpresso Special Deal + Special 51% Discount Save $660 + 180 Days Money Back Guarantee FitSpresso Herpesyl Five Star A dietary product formulated to assist users in reducing weight can increase other advantages that can support overall health. This product can assist users in getting closer to the desirable body weight. Regular Price: 149/per bottle Only for: $39/per bottle Buy Now What IsFitSpresso? FitSpresso is promoted as a natural supplement that comes in the form of diet pills, and it can aid in rapid and efficient weight loss, similar to many other supplements. The term "natural supplements refers to a nutritional supplement that is made entirely of natural, chemical-free materials. You can utilize these organic ingredients to aid in natural weight loss. It can speed up your body's metabolism and assist with other crucial processes. All parts of our bodies are impacted by weight increase, and not only do we need to deal with the increased weight, but we also need to deal with the numerous problems and illnesses that come along with it. This refers to the risk of developing chronic cardiac conditions, low blood pressure, and, in some circumstances, problems with blood sugar. However, FitSpresso even with its bright and bold claims, can help you efficiently manage your weight and completely avoid these extra uncomfortable problems. FitSpresso is a supplement that comes in the form of a pill, which makes it tasty, simple to swallow, and handy. According to the manufacturer, these diet tablets are GMO-free and toxic-free, making them edible. This is why we have things such as weight loss supplements. Thanks to modern advancements, we can just take a dietary supplement pill to bring about significant weight loss in a completely healthy and natural manner. Not only this, but dietary supplements can also support healthy blood sugar levels and help with
Nathan Goodyear

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors - 0 views

www.ncbi.nlm.nih.gov/...PMC3607061

carnitine L-Carnitine Acetyl-L-carnitine depression

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    rat model finds fast, long-lasting benefit of acetyl carnitine in depression.
Nathan Goodyear

Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease - 0 views

www.crd.york.ac.uk/...ShowRecord.asp

Acetyl-L-carnitine acetyl Carnitine cognition cognitive decline brain alzheimer disease

shared by Nathan Goodyear on 04 Nov 13 - No Cached
  • Nathan Goodyear on 04 Nov 13
     
    Meta-analysis of 21 studies on acetyl Carnitine finds improvement with mild cognitive impairment and/or prevention of cognitive deterioration.
Nathan Goodyear

Acetyl-L-carnitine treatment increases choline ace... [Brain Res. 1994] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8137174

Acetyl-L-carnitine carnitine brain acetylcholine nerve growth factor

shared by Nathan Goodyear on 04 Nov 13 - No Cached
  • Nathan Goodyear on 04 Nov 13
     
    Rat study, but acetyl-L-carnitine shown to increase nerve growth factor.  In addition, it increased acetylcholine activity.
Nathan Goodyear

Selenium and L-carnitine reduce oxidative stress in the heart of rat induced by 2.45-GHz radiation from wireless devices. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21360060

carnitine selenium heart health cardiovascular disease

shared by Nathan Goodyear on 11 Apr 17 - No Cached
  • Nathan Goodyear on 11 Apr 17
     
    animal study finds high dose Carnitine plus selenium protects against oxidative stress of the heart.
Nathan Goodyear

L-Carnitine Improves the Asthma Control in Children with Moderate Persistent Asthma - 0 views

www.hindawi.com/...509730

asthma L-carnitine children

shared by Nathan Goodyear on 31 Jul 12 - No Cached
  • Nathan Goodyear on 31 Jul 12
     
    L-carnitine is effective as adjunct in the treatment of moderate persistent asthma.
Nathan Goodyear

l-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial - 0 views

ajcn.nutrition.org/...1738.short

carnitine memory fatigue brain

shared by Nathan Goodyear on 02 Nov 13 - No Cached
  • Nathan Goodyear on 02 Nov 13
     
    Carnitine improves cognition and lessens mental fatigue in centenarians.  
Nathan Goodyear

Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study - 0 views

www.ajcn.org/...799.abstract

Acetyl-L-carnitine fatigue

shared by Nathan Goodyear on 24 May 11 - No Cached
  • decrease in the severity of both mental and physical fatigue and an increase in physical activity
  • Nathan Goodyear on 24 May 11
     
    Acetyl-L-carnitine reduces fatigue
Nathan Goodyear

TJEM : Vol. 224 (2011) , No. 3 pp.209-213 - 0 views

www.jstage.jst.go.jp/..._article

L-carnitine anti-oxidant oxidant free-radicals SOD catalase glutathione perioxidase

shared by Nathan Goodyear on 01 Dec 11 - No Cached
  • Nathan Goodyear on 01 Dec 11
     
    L-carnitine shown to increase antioxidant levels of catalase, SOD, and glutathione perioxidase
Nathan Goodyear

A prospective double-blind, randomized clinical tr... [Med Sci Monit. 2011] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...21629200

L-Carnitine Autism Spectrum Disorder

shared by Nathan Goodyear on 01 Aug 11 - No Cached
  • Nathan Goodyear on 01 Aug 11
     
    L-Carnitine improves Autism Spectrum Disorder
Nathan Goodyear

Multicentre study of l-alpha-glyceryl-ph... [Drugs Aging. 1993 Mar-Apr] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8477148

alpha GPC alpha-GPC Acetyl-L-carnitine dementia Alzheimer's disease aging brain

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    alpha-GPC and to a lesser degree acetyl-l-carnitine improved dementia in multi-center trial.
Nathan Goodyear

Evaluation of atorvastatin efficacy and toxicity on spermatozoa, accessory glands and gonadal hormones of healthy men: a pilot prospective clinical trial - 0 views

www.ncbi.nlm.nih.gov/...PMC4114109

statin statin therapy statins sperm men male fertility atorvastatin hormones

shared by Nathan Goodyear on 04 Sep 14 - No Cached
  • Nathan Goodyear on 04 Sep 14
     
    I really don't understand the purpose of this study.  Why give "healthy" men with normal lipids atorvastatin???  The study found a reduction in TC and LDL, but also a reduction in sperm number, decreased sperm vitality, increased sperm morphology, decreased prostatic acid pho sphatases, epididymal neutral alpha-glucosidase and L-carnitine levels resulted.  
Nathan Goodyear

VITAMINS AND ENTACAPONE IN LEVODOPA-INDUCED HYPERHOMOCYSTEINEMIA: A RANDOMIZED CONTROLLED STUDY - 0 views

www.neurology.org/...1440.extract

Levodopa parkinson's disease Parkinson's homocysteine neurodegenerative disease vitamins

shared by Nathan Goodyear on 26 Jun 12 - No Cached
  • Nathan Goodyear on 26 Jun 12
     
    It appears that Levodopa administration in those with Parkinson's disease will deplete methylation (SAMe), and thus increase homocysteine, which is a neurotoxin.  Additionally, depletion of methylation is associated with depression, commonly seen in Parkinson's disease
Nathan Goodyear

Branched Chain Amino Acid Supplementation for Patients with Cirrhosis | Clinical Correlations - 0 views

www.clinicalcorrelations.org/?p=3544

BCCA branched chain amino acids liver cirrhosis hepatitis amino acids

shared by Nathan Goodyear on 05 Oct 15 - No Cached
  • low level of BCAAs in patients with cirrhosis is hypothesized to be one of multiple factors responsible for development of hepatic encephalopathy
  • supplementation of BCAAs is thought to facilitate ammonia detoxification by supporting synthesis of glutamine, one of the non-branched chain amino acids, in skeletal muscle and in the brain as well as diminishing the influx of AAAs across the blood-brain barrier
  • oral BCAA supplementation is more useful in chronic encephalopathic patients than is parenteral BCAA supplementation in patients with acute encephalopathy
  • ...35 more annotations...
  • malnutrition progressing to cachexia is another common manifestation of cirrhosis
  • Malnutrition can be mitigated with BCAA supplementation
  • Studies show that administration of amino acid formulas enriched with BCAAs can reduce protein loss, support protein synthesis, and improve nutritional status of patients with chronic liver disease
  • Leucine has been shown to be the most effective of the BCAAs because it acts via multiple pathways to stimulate protein synthesis
  • BCAAs metabolites inhibit proteolysis
  • Patients with cirrhosis have both insulin deficiency and insulin resistance
  • BCAAs (particularly leucine) help to reverse the catabolic, hyperglucagonemic state of cirrhosis both by stimulating insulin release from the pancreatic β cells and by decreasing insulin resistance allowing for better glucose utilization
  • Coadministration of BCAAs and glucose has been found to be particularly useful
  • BCAA supplementation improves protein-energy malnutrition by improving utilization of glucose, thereby diminishing the drive for proteolysis, inhibiting protein breakdown, and stimulating protein synthesis
  • Cirrhotic patients have impaired immune defense, characterized by defective phagocytic activity and impaired intracellular killing activity
  • another effect of BCAA supplementation is improvement of phagocytic function of neutrophils and possibly improvement in natural killer T (NKT) cell lymphocyte activity
  • BCAA supplementation may reduce the risk of infection in patients with advanced cirrhosis not only through improvement in protein-energy malnutrition but also by directly improving the function of the immune cells themselves
  • BCAA administration has also been shown to have a positive effect on liver regeneration
  • A proposed mechanism for improved liver regeneration is the stimulatory effect of BCAAs (particularly leucine) on the secretion of hepatocyte growth factor by hepatic stellate cells
  • BCAAs activate rapamycin signaling pathways which promotes albumin synthesis in the liver as well as protein and glycogen synthesis in muscle tissue
  • Chemical improvement with BCAA treatment is demonstrated by recovery of serum albumin and lowering of serum bilirubin levels
  • long-term oral BCAA supplementation was useful in staving off malnutrition and improving survival by preventing end-stage fatal complications of cirrhosis such as hepatic failure and gastrointestinal bleeding
  • The incidence of death by any cause, development of liver cancer, rupture of esophageal varices, or progression to hepatic failure was decreased in the group that received BCAA supplementation
  • Patients receiving BCAA supplementation also have a lower average hospital admission rate, better nutritional status, and better liver function tests
  • patients taking BCAA supplementation report improved quality of life
  • BCAAs have been shown to mitigate hepatic encephalopathy, cachexia, and infection rates, complications associated with the progression of hepatic cirrhosis
  • BCAAs make up 20-25% of the protein content of most foods
  • Highest levels are found in casein whey protein of dairy products and vegetables, such as corn and mushrooms. Other sources include egg albumin, beans, peanuts and brown rice bran
  • In addition to BCAAs from diet, oral supplements of BCAAs can be used
  • Oral supplementation tends to provide a better hepatic supply of BCAAs for patients able to tolerate PO nutrition as compared with IV supplementation, especially when treating symptoms of hepatic encephalopathy
  • Coadministration of BCAAs with carnitine and zinc has also been shown to increase ammonia metabolism further reducing the encephalopathic symptoms
  • Cirrhotic patients benefit from eating frequent, small meals that prevent long fasts which place the patient in a catabolic state
  • the best time for BCAA supplementation is at bedtime to improve the catabolic state during starvation in early morning fasting
  • A late night nutritional snack reduces symptoms of weakness and fatigability, lowers postprandial hyperglycemia, increases skeletal muscle mass,[25] improves nitrogen balance, and increases serum albumin levels.[26] Nocturnal BCAAs even improve serum albumin in cirrhotic patients who show no improvement with daytime BCAAs
  • Protein-energy malnutrition (PEM), with low serum albumin and low muscle mass, occurs in 65-90% of cases of advanced cirrhosis
  • hyperglucagonemia results in a catabolic state eventually producing anorexia and cachexia
  • BCAAs are further depleted from the circulation due to increased uptake by skeletal muscles that use the BCAAs in the synthesis of glutamine, which is produced in order to clear the ammonia that is not cleared by the failing liver
  • patients with chronic liver disease, particularly cirrhosis, routinely have decreased BCAAs and increased aromatic amino acids (AAAs) in their circulation
  • Maintaining a higher serum albumin in patients with cirrhosis is associated with decreased mortality and improved quality of life
  • the serum BCAA concentration is strongly correlated with the serum albumin level
  • Nathan Goodyear on 05 Oct 15
     
    great review of cirrhosis and BCCA supplementation.
Nathan Goodyear

Lipoprotein(a) as a cardiovascular risk factor: current status - 0 views

eurheartj.oxfordjournals.org/...2844.full

cardiovascular risk disease lipoprotein a Lp(a) LDL lipoprotein(a) niacin

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Lipoprotein(a) is a plasma lipoprotein consisting of a cholesterol-rich LDL particle with one molecule of apolipoprotein B100 and an additional protein, apolipoprotein(a)
  • Elevated Lp(a) levels can potentially increase the risk of CVD (i) via prothrombotic/anti-fibrinolytic effects as apolipoprotein(a) possesses structural homology with plasminogen and plasmin but has no fibrinolytic activity and (ii) via accelerated atherogenesis as a result of intimal deposition of Lp(a) cholesterol, or both
  • evidence suggests that apolipoprotein(a) adducts extracellularly and covalently to apolipoprotein B100-containing lipoproteins, predominantly LDL
  • ...2 more annotations...
  • Lp(a) is relatively refractory to both lifestyle and drug intervention.
  • Other agents reported to decrease Lp(a) to a minor degree (<10%) include aspirin, l-carnitine, ascorbic acid combined with l-lysine, calcium antagonists, angiotensin-converting enzyme inhibitors, androgens, oestrogen, and its replacements (e.g. tibolone), anti-estrogens (e.g. tamoxifen), and thyroxine replacement in hypothyroid subjects
  • Nathan Goodyear on 06 Aug 14
     
    full article on the previously posted abstract on Lp(a).  
Nathan Goodyear

Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy - 1 views

www.ncbi.nlm.nih.gov/...PMC5067498

DCA dichloroacetate dichloracetic acid cancer colon cancer

shared by Nathan Goodyear on 18 Jan 18 - No Cached
  • inhibition of mitochondrial pyruvate dehydrogenase kinase
  • inhibition of aerobic glycolysis (the Warburg effect) and activation of mitochondrial potassium ion channels
  • angiogenesis blockade
  • ...5 more annotations...
  • changes in expression of HIF1-α
  • alteration of pH regulators V-ATPase and MCT1, and other cell survival regulators such as PUMA, GLUT1, Bcl2 and p53
  • DCA as a cancer stabilizing agent
  • A protocol of natural medications was developed to address the dose-limiting neurologic toxicity, in collaboration with a naturopathic physician (Andrews). The oral DCA regimen that was developed included three natural medications acetyl L-carnitine[29-31], R-alpha lipoic acid[32-34] and benfotiamine[35-37], for the primary purpose of neuropathy prevention
  • measurable benefits from DCA therapy in 60%-70% of cases
  • Nathan Goodyear on 18 Jan 18
     
    Good review of dichloracetate or DCA in antitumor activity.  DCA has been shown to have numerous anticancer properties.
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