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A cross-sectional study of 1,458 men over a 13 years found an increase risk of diabetes incidence with elevated Estradiol and Estrone levels.  The greatest association was found with Estrone.  This should come as no surprise to anybody as type II diabetes is clearly associated with increasing weight and this is the source of 80% of estrogen production in men.

Estrogen reduces testosterone production in men

good discussion of low T effect on a man's metabolism: particularly muscle mass.

Stretch marks are formed deep within the dermis layer and happen due to rapid stretching, this causes damage to the skin's connecting tissues. To get rid of these stretch marks we are introducing to you our latest laser treatment i.e. PIXIGENUS. It is a unique technology to eliminate stretchmarks from various parts of the body. Watch the full video to know more. Stretch marks are caused because of rapid stretching of the skin that results into scars and discoloration of the skin. There are many reasons which can lead to stretch marks such as rapid weight reduction, quick weight gain, excessive exercise, steroids, pregnancy, hormonal changes, puberty etc. Millions of women have stretch marks, but this fact does little to lessen the embarrassment that most women feel at the appearance of these unattractive striations on their skin. Stretch marks, also known as striae, are a form of scarring on the skin with an off-color hue. Over time they may reduce, but will not disappear completely. Tearing of the dermis results into stretch marks.

discussion of the declining levels of androgens in the aging male.  But the focus of this entire article is wrong.  They are focusing on the blood levels of these androgens.  The biological effects of hormones occur in tissue not blood.  Though this article provides a good discussion of how transport of androgens are effected, it falls far short of providing any useful clinical application, because it fails to discuss peripheral levels of androgens.  

This study shows that DHT is a good alternative androgen to Testosterone.  It was shown to have no positive/negative effect on the prostate.  The negative of this study was found to be bone loss from supra physiologic DHT.  The point there is to keep hormone replacement physiologic, as one should with all BHRT.

Increasing glucose levels associated with declining LH pulses in men with type II diabetes.  This is one proposed mechanism for low T in men.  There has been great debate about if Low T was in part the cause of Diabetes or an effect of diabetes.  This proposes that low T is due to a decreased LH pulse as a result of rising glucose.

Causes of itching For men, the cause of the itch can be divided into three groups: * The "little boy" hygiene is not right: Men - especially young people - often do not focus or "lazy" to clean the boy. This bad habit has gradually created an environment for the growth of genital fungi, causing an itching sensation. Besides, the selection of inappropriate cleaning solutions is also the reason that may be encountered in men. Some men reported using feminine cleaning solutions or shower gels to "bath" their "boy". This makes the itching condition more and more because the nature of the feminine hygiene solution is not suitable for his small skin, so it can easily lead to skin irritation, even leading to a disorder of the skin and creating favorable conditions for mushroom growth.

Impact of obesity on infertility and sex hormone production in men.

Italian study projects an increase in the number of men with hypogonadism.  This will follow an increase in obesity, CVD and type II diabetes.

Good, but limited study to the incidence of low T in men.  

Presentation of a familial incidence of male gynecomastia and hypogonadotropic hypogonadism via peripheral aromatase activity.

DHT binds to androgen receptor with higher affinity and stays bound with receptor up to 5 x longer.

Here is the full article.

Article reviews the link between obesity, low T, metabolic syndrome and ED.  ED has been shown to be predictive of CVD by 3-5 years.  

long standing low T linked to bradycardia and heart failure in case series.  Exact relationship of cause/effect unknown, though low T has been shown to be associated with wide spectrum of increased risk of CVD.

low T associated with increased risk of type II Diabetes and Metabolic Syndrome.

Low physical activity and low TT in men associated with oxidized LDL.

High Estradiol is reproducible finding in men with Diabetes.  Link to MI not able to be determined.

severe hypogonadism was associated with a 5 fold increase risk of cardiovascular mortality and all cause mortality in men ages 40-79 in European study.