Skip to main content

Home/ Dr. Goodyear/ Group items matching ""disease alzheimer's Parkinson's"" in title, tags, annotations or url

Group items matching
in title, tags, annotations or url

Sort By: Relevance | Date Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18463003

mitochondria aging neurodegenerative disease Alzheimer's Parkinson's Huntington's ALS

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • Nathan Goodyear on 07 Feb 11
     
    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

SpringerLink - NeuroMolecular Medicine, Volume 10, Number 4 - 0 views

www.springerlink.com/...8r1310q48u375037

mitochondria aging disease neurodegenerative Parkinson's Alzheimer's MS Huntington's

shared by Nathan Goodyear on 07 Mar 11 - No Cached
  • Nathan Goodyear on 07 Mar 11
     
    nice discussion of mitochondria and their implication in aging and neurodegenerative disease
Nathan Goodyear

Glutamate and the glutamate receptor system: a tar... [Int J Geriatr Psychiatry. 2003] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...12973748

glutamate glutamic acid excitotoxicity Parkinson's MS Alzheimer's Huntington's disease neurodegenerative

shared by Nathan Goodyear on 18 Mar 11 - No Cached
  • Under certain conditions, glutamate has a toxic action resulting from an activation of specific glutamate receptors, which leads to acute or chronic death of nerve cells.
  • Nathan Goodyear on 18 Mar 11
     
    deep, heavy read on glutamate excitotoxicity and neuronal death leading to neurodegenerative disease
Nathan Goodyear

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States - 0 views

www.la-press.com/and-healthy-stat-article-a1204

kynurenine pathway neurodegenerative disorders excitotoxicity ALS Parkinson's disease Alzheimer's mood disorder depression anxiety quinolinate picolinate disordered tryptophan metabolism

shared by Nathan Goodyear on 27 Oct 11 - No Cached
  • Nathan Goodyear on 27 Oct 11
     
    review of studies looking at kyneurenine pathway and it's contribution to neurodegenerative disorders and mood disorders
Nathan Goodyear

Hyperbaric oxygen therapy promotes neurogenesis: where do we stand? - 0 views

www.ncbi.nlm.nih.gov/...PMC3231808

hbot hyperbaric therapy hyperbaric brain TBI stroke neurogenesis neuorplasticity

shared by Nathan Goodyear on 18 May 17 - No Cached
  • Numerous in vivo and in vitro studies confirm that HBOT induces neurogenesis
  • HIF-1α is the principal mediator of cellular hypoxia adaptations
  • activated by hypoxia, HIF-1α causes the transcription of its regulated downstream genes, including erythropoietin (EPO) and VEGF which are known to promote neurogenesis
  • ...10 more annotations...
  • The safety of HBOT was also evaluated and it was pointed out that, if given at proper paradigms, like 1.5 ATA for 60 minutes, HBOT will not cause oxygen toxicity
  • Rockswold et al., on the other hand, found that HBOT might be potentially beneficial for severe TBI patients
  • McDonagh et al., concluded that there was insufficient evidence to establish the effectiveness of HBOT in the treatment of TBI
  • The first multicenter, randomized, double-blind, controlled trial in 2009 found that 40-hour HBOT of 24% oxygen at 1.3 ATM produced significant improvement in children's overall functioning, receptive language, social interaction, eye contact, and sensory/cognitive awareness compared to those received slightly pressurized room air
  • Another study in 2010 on 16 autism patients, adopting a similar treatment paradigm, showed no effect on a wide array of behavioral evaluations
  • To date, there is little evidence that HBOT causes malignant growth or metastasis. A history of malignancy should therefore not be considered as a contraindication for HBOT
  • HBOT enhances the production of reactive oxygen species (ROS) and causes oxidative stress in body tissues
  • Excessive accumulation of oxidative stress may contribute to neurodegenerative processes and cell death in the brain, as seen in diseases like Alzheimer's disease (AD) and Parkinson's disease (PD)
  • Hormesis
  • process that results in a functional improvement of cellular stress resistance, survival, and longevity in response to sub-lethal levels of stress
  • Nathan Goodyear on 18 May 17
     
    great review of hbot, brain injury, neuroplasticity and neurogenesis.
Nathan Goodyear

Oxidative stress and neurodegeneration: where are we now? - Halliwell - 2006 - Journal of Neurochemistry - Wiley Online Library - 0 views

onlinelibrary.wiley.com/...full

oxidative damage oxidative stress detoxification CNS neurodegeneration neurodegenerative disease Free radicals Alzheimer's Parkinson's disease ALS MS

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    Fantastic review of oxidative damage and the CNS.  This is a 2006 review of our understanding of how neurodegeneration occurs through oxidative stress and of course poor detoxification.
Nathan Goodyear

Microglial Activation And Neurodegeneration - 0 views

www.tuberose.com/ationAndNeurodegeneration.html

neurodegeneration neurodegenerative disease excitotoxicity inflammation microglia Parkinson's disease Alzheimer's MS ALS

shared by Nathan Goodyear on 02 Nov 12 - No Cached
  • Nathan Goodyear on 02 Nov 12
     
    short and brief discussion of how microglial inflammation cause neurodegeneration via excitotoxicity.  Dr. Blaylock is the author of this short article.  
Nathan Goodyear

Coenzyme Q treatment of neurodegenerative diseases... [Mitochondrion. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17485247

CoQ10 Parkinson's ALS Huntington's Alzheimer's disease

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 shows promise in neurodegenerative disorders
Nathan Goodyear

Aluminum induced immunoexcitotoxicity in neurodevelopmental and neurodegenerative disorders - 0 views

www.geoengineeringwatch.org/...Aluminum-Blaylock.pdf

Aluminum immunoexcitotoxicity neurodegenerative disease disorders glial microglia astrocytes glutathione Alzheimer's Parkinson's MS

shared by Nathan Goodyear on 26 Nov 13 - No Cached
  • Nathan Goodyear on 26 Nov 13
     
    Great review of the scientific evidence of Aluminum in microglial activation and immunoexcitotoxicity and neurodegeneration of the brain.
Nathan Goodyear

Mitochondrial dynamics in cell death and neurodege... [Cell Mol Life Sci. 2010] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...20577776

mitochondrial neurodegenerative disorders alzheimer's parkinson's disease Huntington's

shared by Nathan Goodyear on 14 Jan 11 - No Cached
  • abnormal mitochondrial dynamics relevant to neuronal synaptic loss and cell death in neurodege
  • Nathan Goodyear on 14 Jan 11
     
    Mitochondrial dynamics in cell death and neurodegeneration.
Nathan Goodyear

Characterization of the Kynurenine Pathway in Human Neurons - 0 views

www.jneurosci.org/...12884.full

disordered tryptophan metabolism kynurenine pathway quinolinate picolinate neurodegenerative disorders excitotoxicity ALS Parkinson's disease Alzheimer's depression

shared by Nathan Goodyear on 27 Oct 11 - No Cached
  • Nathan Goodyear on 27 Oct 11
     
    review of the kynurenine pathway 
‹ Previous 21 - 31 of 31
Showing 20▼ items per page