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Nathan Goodyear

Vitamin E Protects Against Oxidative Damage and Learning Disability After Mild Traumati... - 0 views

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    Animal study: vitamin E protects against mild TBI
Nathan Goodyear

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-indu... - 0 views

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    Omega 3 supplementation found to blunt microglial TBI inflammation. 
Nathan Goodyear

Hyperbaric oxygen therapy for traumatic brain injury - 0 views

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    great review article on the positive effects of hbot in TBI
Nathan Goodyear

Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumat... - 0 views

  • The changes in SPECT images after treatment indicate that HBOT led to reactivation of neuronal activity in stunned areas that seemed normal under CT and MRI imaging. While SPECT imaging has a limited spatial resolution (compared, for example, to fMRI), the changes in activity were sufficiently robust to be clearly detected by the SPECT images.
  • HBOT might initiate a cellular and vascular repair mechanism and improve cerebral vascular flow
  • HBOT induces regeneration of axonal white matter [61], [62], [63], [64], has positive effect upon the myelinization and maturation of injured neural fibers [65], and can stimulate axonal growth and increase the ability of neurons to function and communicate with each other
  • ...6 more annotations...
  • HBOT was found to have a role in initiation and/or facilitation of angiogenesis and cell proliferation processes needed for axonal regeneration [67].
  • The observed reactivation of neuronal activity in the stunned areas found here, along with similar results in post-stroke patients
  • At the cellular level, HBOT can improve cellular metabolism, reduce apoptosis, alleviate oxidative stress and increase levels of neurotrophins and nitric oxide through enhancement of mitochondrial function (in both neurons and glial cells)
  • HBOT may promote the neurogenesis of endogenous neural stem cells
  • With regard to secondary injury mechanisms in mTBI, HBOT can initiate vascular repair mechanism and improve cerebral vascular flow [58], [59], [68], [69], promote blood brain barrier integrity and reduce inflammatory reactions [28] as well as brain edema
  • It might be possible that HBOT enables the metabolic change simply by supplying the missing energy/oxygen needed for those regeneration processes.
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    Hbot therapy, according to study, induces neuroplasticity and improves brain function in post concussion syndrome and those with mTBI.  The important point about this study was that the study was done years after the injury; what if the therapy was employed immediately after...
Nathan Goodyear

Interleukin-10 mediates the neuroprotection of hyperbaric oxygen therapy against trauma... - 0 views

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    abstract of animal study finds that hyperbaric therapy provides neuroprotection via increase in IL-10; improved blood-brain barrier, improved tight junctions were about of the benefit found.
Nathan Goodyear

Therapeutic effects of progesterone and its metabolites in traumatic brain injury may i... - 0 views

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    Progesterone and its metabolite allopregnanolone show promise in protecting the brain in TBI.
felipp windsor

Toothache Taken Care Of - 1 views

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dental care windsor

started by felipp windsor on 02 Jul 13 no follow-up yet
Nathan Goodyear

Ketogenic Diet - Nutrition and Traumatic Brain Injury - NCBI Bookshelf - 0 views

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    good review of the impact of ketones on TBI.  The authors conclude that precursors to ketones may be the right approach to treatment.  This would be MCT's and ketones.
Nathan Goodyear

Fasting is neuroprotective following traumatic brain injury - Davis - 2008 - Journal of... - 0 views

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    short term fasting and ketosis provides neuroprotection and preserves mitochondria in animal TBI study.  This study found preventative effects of the ketones.
Nathan Goodyear

High School Football and Risk of Neurodegeneration: A Community-Based Study - Mayo Clin... - 0 views

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    Study finds increased TBI in high school football players, but not an increase in neurodegenerative disease.
Nathan Goodyear

Posttraumatic Stress Disorder: Does the Gut Microbiome Hold the Key? - 0 views

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    Gut microbiome diversity is different in stressed mice and calm mice in animal study.  Authors propose intricate connection between gut:brain and possible evaluation and therapy in PTSD.
Nathan Goodyear

The epidemiology of sports-related tra... [J Head Trauma Rehabil. 1998] - PubMed - NCBI - 0 views

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    analysis of sports related TBI
Nathan Goodyear

Review: Contact sport-related chr... [Neuropathol Appl Neurobiol. 2011] - PubMed - NCBI - 0 views

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    CTE and sports related injuries
Nathan Goodyear

Immunoexcitotoxicity offers new insight in brain injury related research, care - 0 views

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    Great, though brief, review of immunoexcitotoxicity as it relates to CTE.
Nathan Goodyear

SLC6A4 methylation modifies the effect of the number of traumatic events on risk for po... - 0 views

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    lower methylation status increases risk of PTSD.  Those with PTSD should be evaluated for methylation status.
Nathan Goodyear

Progesterone and allopregnanolone reduce inflamma... [Exp Neurol. 2004] - PubMed - NCBI - 0 views

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    progesterone and allopregnanolone shown to reduce IL-1beta and TNF-alpha in TBI rat model.
Nathan Goodyear

Progesterone treatment inhibits the inflammatory a... [Brain Res. 2005] - PubMed - NCBI - 0 views

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    progesterone shown to decrease NF-KappaB and other inflammatory signaling after TBI in rat model. Part of the role of progesterone is as an anti-inflammatory.
Nathan Goodyear

The Neurosteroid Allopregnanolone Promotes Proliferation of Rodent and Human Neural Pro... - 0 views

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    allopregnanolone increases human neural stem cells. Not only does allopregnanolone reduce inflammation, it plays a role in neurogenesis and thus recovery.
Nathan Goodyear

Journal of Traumatic Stress, Volume 3, Number 3 - SpringerLink - 0 views

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    sleep disruption is a major symptom in those with PTSD.  There is no greater stress than combat.  The majority of research on PTSD is done on combat veterans
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