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Nathan Goodyear

TSH may not be a good marker for adequate thyroid ... [Wien Klin Wochenschr. 2005] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...16416346

TSH thyroid hormone replacement therapy

shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • TSH levels used to monitor substitution, mostly regulated by intracellular T3 in the pituitary, may not be such a good indicator of adequate thyroid hormone action in all tissues
  • Nathan Goodyear on 16 Dec 10
     
    TSH may not be a good marker for adequate thyroid hormone replacement therapy.
Nathan Goodyear

Peripheral metabolism of thyroid hormones: a revie... [Altern Med Rev. 2000] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...10956378

hypothyroidism hypothyroid T4 T3

shared by Nathan Goodyear on 20 Dec 10 - No Cached
  • The common feature of these disorders is a low level of circulating T3, with generally normal to slightly elevated blood T4 levels and either normal or slightly suppressed TSH levels. This pattern of altered thyroid hormone levels is generally agreed to be a result of impairment in extra-thyroidal peripheral metabolism
  • Nathan Goodyear on 20 Dec 10
     
    thyroid replacement is not just about T4 (synthroid); but about T3, which is 5.4 x more potent
Nathan Goodyear

Thyroid hormone attenuates cardiac remodeling and ... [Eur J Cardiothorac Surg. 2007] -... - 0 views

www.ncbi.nlm.nih.gov/...17560116

thyroid hormone Cardiovascular disease

shared by Nathan Goodyear on 02 Feb 11 - No Cached
  • CONCLUSIONS: Thyroid hormone administration early after infarction attenuates cardiac remodeling and significantly improves myocardial performance.
  • Nathan Goodyear on 02 Feb 11
     
    Wow, Thyroid replacement after MI, improves heart function and reduces damage
Nathan Goodyear

Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid ... - 0 views

onlinelibrary.wiley.com/...abstract

thyroid hypothyroid hypothyroidism leptin obesity overweight

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • The data are consistent with the hypothesis that leptin and the pituitary–thyroid axis interact in the euthyroid state, and that hypothyroidism reversibly increases leptin concentrations
  • Nathan Goodyear on 08 Mar 11
     
    thyroid and leptin interact to control weight
Nathan Goodyear

Serum leptin concentrations in patients with thyroid disorders - Yoshida - 2001 - Clini... - 0 views

onlinelibrary.wiley.com/...full

leptin thyroid hormone obesity overweight

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • These results indicate that thyroid hormone may play an important role in the appropriate secretion of leptin in humans.
  • Nathan Goodyear on 08 Mar 11
     
    thyroid hormone plays role in stimulating leptin secretion
Nathan Goodyear

Franken-Thyroxine Making Your Thyroid Condition Worse? | GreenMedInfo | Blog entry | Na... - 0 views

www.greenmedinfo.com/...g-your-thyroid-condition-worse

thyroid synthroid bioidentical Thyroxine hormone

shared by Nathan Goodyear on 01 Aug 11 - No Cached
  • Nathan Goodyear on 01 Aug 11
     
    synthroid is not biodentical Thyroxine (thyroid) hormone
Nathan Goodyear

[Effects of lead on thyroid function of occupation... [Zhonghua Lao Dong Wei Sheng Zhi ... - 0 views

www.ncbi.nlm.nih.gov/...14761528

lead exposure thyroid hypothyroid T3

shared by Nathan Goodyear on 05 Jul 11 - No Cached
  • e workers with higher level of blood lead (> 2.88 micro mol/L) showed lower levels of T(3) [(1.54 +/- 0.39) nmol/L] and FT(3)
  • Higher level of blood lead may cause certain damage to thyroid function by inhibiting deiodination of T(4)
  • Nathan Goodyear on 05 Jul 11
     
    occupational lead exposure and thyroid dysfunction
Nathan Goodyear

Thyroid Replacement Therapy and Heart Failure - 0 views

circ.ahajournals.org/...385.full

thyroid T3 hormone hormones cardiovascular disease heart health failure CHF MI myocardial infarction heart attack heart disease

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • A good biomarker of intracardiac TH signaling would be helpful but has not been identified. In the absence of such a marker, a rational, cautious therapeutic approach might be to restore and maintain over time biochemical euthyroidism as documented by normal circulating levels of TSH, FT4, and FT3.
  • a low-T3 state resulting from altered peripheral TH metabolism secondary to caloric restriction is associated with impaired cardiac contractility
  • Low-T3 syndrome is the central finding and defines the illness in a variety of acute and chronic severe nonthyroidal illnesses with cardiac origin, including MI, HF, and surgically treated cardiac disease.1 Low circulating levels of T3 in the absence of primary thyroid hypofunction have been found in 20% to 30% of patients with dilated cardiomyopathy.
  • ...1 more annotation...
  • FT3 levels were inversely correlated to coronary artery disease
  • Nathan Goodyear on 24 Sep 14
     
    Great review of the current understanding of thyroid hormone metabolism in cardiac tissue.  Low T3 and increased rT3 (via increased D3 activity) is CLEARLY associated with poor cardiac performance and post MI and CHF is associated with poor outcomes.  T3 is critical in cardiac remodeling and recovery post MI.  T3 is actually a vasodilatory in the coronary arteries.   Why a endocrinologist would call rT3 useless only points to their ignorance of the literature.
Nathan Goodyear

High prevalence of Hashimoto's thyroiditis in patients with polycystic ovary syndrome: ... - 0 views

www.ncbi.nlm.nih.gov/...25822940

Hashimoto's thyroiditis autoimmune disease thyroid disease PCOS Estradiol Progesterone women female hormone hormones

shared by Nathan Goodyear on 13 Apr 15 - No Cached
  • Nathan Goodyear on 13 Apr 15
     
    Hashimoto's thyroid disease associated with PCOS in women; this was found to be associated with an increased Estradiol:Progesterone ratio.  
Nathan Goodyear

Low Levels of Serum Vitamin D3 Are Associated with Autoimmune Thyroid Disease in Pre-Me... - 0 views

www.ncbi.nlm.nih.gov/...PMC3993051

vitamin D TPO autoimmune autoimmune disease autoimmune thyroid disease thyroid hormones

shared by Nathan Goodyear on 07 Feb 16 - No Cached
  • Nathan Goodyear on 07 Feb 16
     
    low vitamin D associated with increased autoimmune thyroid TPO antibodies in women.  This association was found in pre menopause women, but not post menopause women.
Nathan Goodyear

Possible association between thyroid autoimmunity and Menière's disease - 0 views

www.ncbi.nlm.nih.gov/...PMC2384067

hypothyroid hypothyroidism autoimmune thyroid disease thyroid meniere's disease inflammation

shared by Nathan Goodyear on 08 Dec 15 - No Cached
  • Nathan Goodyear on 08 Dec 15
     
    study finds correlation between autoimmune thyroid disease and Meniere's disease
Nathan Goodyear

Thyroid Nodules - 0 views

www.ncbi.nlm.nih.gov/...PMC3575959

thyroid thyroid nodules low iodine iodine hormones

shared by Nathan Goodyear on 10 Jan 16 - No Cached
  • Nathan Goodyear on 10 Jan 16
     
    good review on thyroid nodules, causes, and implications.
Nathan Goodyear

Association of melasma with thyroid autoimmunity and other thyroidal abnormalities and ... - 0 views

www.ncbi.nlm.nih.gov/...3923030

melasma hypothyroidism autoimmune thyroid TPO

shared by Nathan Goodyear on 18 Oct 16 - No Cached
  • Nathan Goodyear on 18 Oct 16
     
    melasma and autoimmune thyroid disease.  
Nathan Goodyear

Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US nati... - 0 views

www.bmj.com/bmj.i6865

thyroid disease thyroid functional hypothyroidism hypothroidism fertility infertility

shared by Nathan Goodyear on 13 Mar 17 - No Cached
  • Nathan Goodyear on 13 Mar 17
     
    Thyroid therapy in women with subclinical hypothyroidism found to have improved pregnancy rates (lower pregnancy loss).
Nathan Goodyear

Thyroid Hormone Receptor Agonists Reduce Serum Cholesterol Independent of the LDL Receptor - 0 views

endo.endojournals.org/...6136.abstract

LDL cholesterol T3 thyroid hormone hormones receptor receptors

shared by Nathan Goodyear on 28 Nov 12 - No Cached
  • Nathan Goodyear on 28 Nov 12
     
    New study shows that T3 and thyroid hormone agonists reduce LDL.  This is independent that LDL receptors.  Previously, it was thought that T3 increased LDL receptor expression.  But, this study shows that T3 lowers LDL independent of the LDL receptors.  
Nathan Goodyear

Thyroid hormones act indirectly to increase sex hormone-binding globulin prod... - 0 views

jme.endocrinology-journals.org/...19.full

thyroid hormones hypothyroid hyperthyroid SHBG liver

shared by Nathan Goodyear on 10 Dec 12 - No Cached
  • Nathan Goodyear on 10 Dec 12
     
    Thyroid hormones stimulate SHBG levels.  
Nathan Goodyear

The thyroid hormone, parathyroid hormone and vitamin D associated hypertension - 0 views

www.ncbi.nlm.nih.gov/...PMC3230087

thyroid hormone vitamin vitamin d hypertension

shared by Nathan Goodyear on 15 May 13 - No Cached
  • Nathan Goodyear on 15 May 13
     
    Good review of the hypertension (different) found in those with thyroid problems, parathyroid problems, and low vitamin D.
Nathan Goodyear

Influence of Thyroid Hormone on Progesterone Transformation in Man - 0 views

jcem.endojournals.org/...831.abstract

thyroid hormone progesterone man hormones

shared by Nathan Goodyear on 03 Jun 13 - No Cached
  • Nathan Goodyear on 03 Jun 13
     
    hormones effect each other.  In this study, thyroid found to effect progesterone metabolism in men.
Nathan Goodyear

Thyrotropin suppression by metformin in a cohort of patients with differentiated thyroi... - 0 views

www.endocrine-abstracts.org/...ea0020p141.htm

TSH thyroid metformin

shared by Nathan Goodyear on 31 Jan 13 - No Cached
  • Nathan Goodyear on 31 Jan 13
     
    Again, showing that metformin suppresses TSH secretion without change in actual thyroid hormone levels.  We know that inflammation plays a role in HPA suppression, why not with TSH?
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