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Nathan Goodyear

A Review of the Clinical Consequences of Variation in Thyroid Function Within the Refer... - 0 views

jcem.endojournals.org/...3562.abstract

thyroid function

shared by Nathan Goodyear on 02 Oct 13 - No Cached
  • Nathan Goodyear on 02 Oct 13
     
    study finds variation of thyroid values within the reference range have physiologic impact.  The point is: just because the values are "normal" does not mean the thyroid function is normal.
Nathan Goodyear

Induction of oral tolerance in human autoimmune thyr... [Thyroid. 1998] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...9545109

T4 T3 autoimmune autoimmune disease immune system thyroid disease

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    combined T4/T3 in desiccated thyroid found to reduce cellular immunity in those with autoimmune thyroid disease.
Nathan Goodyear

Minireview: Thyroid Hormone Transporters: The Knowns and the Unknowns: Molecular Endocr... - 0 views

press.endocrine.org/...me.2010-0095

thyroid hormone receptors hormones

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • the majority of TRs is located in the nucleus
  • Nathan Goodyear on 24 Sep 14
     
    thyroid hormone transportation.  The majority of the thyroid hormone receptors are in the nucleus of the cell.
Nathan Goodyear

Acute myocardial infarction and thyroid function: New pathophysiological and therapeuti... - 0 views

informahealthcare.com/...07853890.2011.573501

thyroid hormone hormones T3 heart attack heart health myocardial infarction MI

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    Thyroid hormone plays significant role in cardiac remodeling after acute myocardial infarction.  Thyroid hormone, particularly T3 as the vast majority of T3 is produced in heart tissue via D1 enzymatic activity, improves cardiac contractility, reduces systemic vascular resistance, reduces cardiac work load, decreases blood pressure, improves cardiac metabolism, and thus improves outcomes post MI.
Nathan Goodyear

EHP - Sulfated Metabolites of Polychlorinated Biphenyls Are High-Affinity Ligands for t... - 0 views

ehp.niehs.nih.gov/1206198

polychlorinated biphenyls PCBs thyroid xenoestrogens hormone hormones

shared by Nathan Goodyear on 19 Jun 13 - No Cached
  • Nathan Goodyear on 19 Jun 13
     
    Polychlorinated biphenyl (PCBs) shown to disrupt thyroid hormone function through disruption of the transthyretin binding sites.  Not only is it a xenoestrogen, but it disrupts thyroid function too.
Nathan Goodyear

Thyroid Disease and the Heart -- Klein and Danzi 116 (15): 1725 -- Circulation - 0 views

circ.ahajournals.org/...1725

thyroid T3 heart cardiovascular hypothyroid hypothyroidism

shared by Nathan Goodyear on 01 Feb 11 - No Cached
  • The importance of the recognition of the effects of thyroid disease on the heart also derives from the observation that restoration of normal thyroid function most often reverses the abnormal cardiovascular hemodynamics
  • Nathan Goodyear on 01 Feb 11
     
    T3 and normalization of thyroid function improves heart function in those with significant heart disease
Nathan Goodyear

Leptin serves body as energy signal | Harvard Gazette - 0 views

news.harvard.edu/...n-serves-body-as-energy-signal

leptin body energy hormones thyroid

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • replacing leptin to physiologically normal levels during fasting fully restored testosterone to baseline, indicating that leptin regulates the hypothalamic-pituitary- gonadal axis that controls the release of testosterone and estrogen
  • Leptin clearly has some effect on the thyroid hormone axis,
  • including thyroid-stimulating hormone and the free-circulating form of thyroid
  • Nathan Goodyear on 08 Mar 11
     
    Leptin regulates hypothalamic-pituitary axis; and don't forget thyroid too.
Nathan Goodyear

Cracking the Code for Thyroid Hormone Signaling - 0 views

www.ncbi.nlm.nih.gov/...PMC3715916

thyroid hormone hormones T3 T4 rT3 reverse T3

shared by Nathan Goodyear on 16 Aug 14 - No Cached
  • Nathan Goodyear on 16 Aug 14
     
    nice review of thyroid physiology.  Good discussion of peripheral thyroid metabolism.
Nathan Goodyear

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling - 0 views

www.ncbi.nlm.nih.gov/...PMC2647704

thyroid hormone T3 T4 rT3 deiodinase selenium hormones

shared by Nathan Goodyear on 10 Nov 14 - No Cached
  • Nathan Goodyear on 10 Nov 14
     
    Anything and everything one would want to know regarding thyroid hormone signaling.  Doctors, especially endocrinologists, need to read this.  T4 is not or is ever inside target cells.  The enzymes, deiodinase types 1, 2, and 3, are what control the thyroid hormone at the cellular levels.  Deiodinase-2 is what generates T3 in the cytosol of the cell.  In contrast, deiodinase-3 is what generates rT3 which is inactive.  High Fat diet increases deiodinase-3.
Nathan Goodyear

The trace element selenium and the thyroid gland. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10403185

Selenium Se thyroid gland function iodine cancer

shared by Nathan Goodyear on 10 Nov 14 - No Cached
  • Nathan Goodyear on 10 Nov 14
     
    Selenium is very important in thyroid function, not just Iodine.  Low Se levels significantly correlate with thyroid cancer.
Nathan Goodyear

Thyroid hormone receptors and resistance to thyroid hormone disorders - 0 views

www.ncbi.nlm.nih.gov/...PMC4578869

receptors" "thyroid hormone thyroid receptors

shared by Nathan Goodyear on 07 Nov 18 - No Cached
  • Nathan Goodyear on 07 Nov 18
     
    Great review on thyroid hormone receptors alpha and beta, which are nuclear receptors.
Nathan Goodyear

Sex Hormone-Binding Globulin in the Diagnosis of Peripheral Tissue Resistance to Thyroi... - 0 views

jcem.endojournals.org/...740.abstract

hypothyroid thyroid thyroid disease T3 T4 SHBG hormone resistance hormones

shared by Nathan Goodyear on 10 Dec 12 - No Cached
  • Nathan Goodyear on 10 Dec 12
     
    T3, and T4 for that matter, increases SHBG.  This would be a novel method to determine thyroid hormone receptor insensitivity or resistance.
Nathan Goodyear

Cardiac Involvement in Thyroid Hormone Resistance - 0 views

jcem.endojournals.org/...204.abstract

thyroid hormone resistance thyroid hormone resistance cardiac heart

shared by Nathan Goodyear on 02 Apr 13 - No Cached
  • Nathan Goodyear on 02 Apr 13
     
    Thyroid hormone resistance has cardiac effects.
Nathan Goodyear

The thyroid : Oxford Textbook of Endocrinology and Diabetes Oxford Medicine - 0 views

oxfordmedicine.com/...med-9780199235292-section-3

thyroid thyroid disease hormones endocrinology

shared by Nathan Goodyear on 02 Apr 13 - No Cached
  • Nathan Goodyear on 02 Apr 13
     
    Chapter of Thyroid from oxford textbook of endocrinology and diabetes
Nathan Goodyear

High prevalence of chronic thyroiditis in patients with polycystic ovary syndrome. - Pu... - 0 views

www.ncbi.nlm.nih.gov/...23548659

PCOS polycystic ovarian syndrome hormones TPO Hashimoto's thyroiditis thyroid

shared by Nathan Goodyear on 14 Jun 16 - No Cached
  • Nathan Goodyear on 14 Jun 16
     
    Autoimmune thyroid present in 1/3 of women with PCOS.
Nathan Goodyear

Metabolic Effects of Liothyronine Therapy in Hypothyroidism: A Randomized, Double-Blind... - 0 views

jcem.endojournals.org/...3466.abstract

T3 T4 hypothyroid hypothyroidism functional armour thyroid cholesterol LDL weight-loss overweight obesity metabolic effects therapy

shared by Nathan Goodyear on 08 Dec 11 - No Cached
  • Nathan Goodyear on 08 Dec 11
     
    T3 shown increase weight loss, lower LDL, decrease apolipoprotein B, decrease T cholesterol versus T4.  This flies in the face of conventional medical dogma, that T 4 (synthroid, levothyroxine) is the only route of thyroid replacement.  In fact, this suppports the use of armour thyroid, a T4/T3 combination.
Nathan Goodyear

Thyroid function and thyroid hormone metabol... [Klin Wochenschr. 1981] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7241955

hypothyroid hypothyroidism TSH T3 syndrome low aging thyroid hormone

shared by Nathan Goodyear on 07 Feb 12 - No Cached
  • Nathan Goodyear on 07 Feb 12
     
    This study doesn't find evidence of low t3-syndrome, but suggests the impairment of TSH secretion (low TSH)is the first potential sign of thyroid dysfunction.
Nathan Goodyear

Combination Treatment with T4 and T3: Toward Personalized Replacement Therapy in Hypoth... - 0 views

jcem.endojournals.org/...2256.abstract

armour thyroid hypothyroid hypothyroidism T4 T3

shared by Nathan Goodyear on 27 Jul 12 - No Cached
  • Nathan Goodyear on 27 Jul 12
     
    Wow!  JCEM states, "...it may be time to consider a personalized regime of thyroid hormone replacement therapy in hypothyroid patents."  Otherwise stated, combination T4, T3 provides a more customized thyroid replacement therapy than synthroid alone.
Nathan Goodyear

Relative vitamin D insufficiency in Hashimoto's thyr... [Thyroid. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21751884

vitamin D vitamin D Hashimoto's thyroiditis hypothyroid hypothyroidism thyroid

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    low vitamin D levels associated with Hashimoto's thyroiditis.
Nathan Goodyear

Effects of Hypo- and Hyperthyroidism on Noradrenergic Activity and Glycerol Concentrati... - 0 views

press.endocrine.org/...jc.2003-030576

thyroid hormone adipose tissue adipose fat obesity metabolism noradrenaline norepinephrine

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    Thyroid hormone increased localized norepinephrine production and liposlys resulting in decreases SQ adipose tissue compared to hypothyroid.  This study showed a localized effect of adipose tissue by thyroid hormone. 
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