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Nathan Goodyear

Effects of hormones on skin wrinkles and rigidity vary by race/ethnicity: fou... - 0 views

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    new study concludes that hormone therapy does not improve skin aging.  Though I would like to see hormone levels evaluated to assure physiologic hormone levels were obtained to conclude this lack of relationship.
Nathan Goodyear

Cigarette smoking and hormones : Current Opinion in Obstetrics and Gynecology - 0 views

  • Epidemiologic studies worldwide have established that exposure to cigarette smoke is an important cause of estrogen deficiency.
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    tobacco smoke alters estrogen metabolism.  Increase in CYP1B1 and CYP1B1 are the result of tobacco smoke.
Nathan Goodyear

Luteal start vaginal micronized progesterone improves pregnancy success in women with r... - 0 views

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    Recurrent early pregnancy losses can be prevented not with provera, not with progestin, but with progesterone. The use of progesterone by the functional medicine movement has long been advocated and supported in the science; now the allopathic medicine will try to claim it as its own.
Nathan Goodyear

Dog sperm quality decline is blamed on pet food chemicals | New Scientist - 0 views

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    26 year study of dogs finds declining sperm count equivalent to that in men.  The decline was found to occur at a rate of 1.2% to 2.5% annually over course of study.  The authors pointed to EDC's in food.
Nathan Goodyear

Caffeine Intake and Semen Quality in a Population of 2,554 Young Danish Men - 0 views

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    high coke intake (defined as 1 L or greater) daily associated with lower sperm count and concentration.  
Nathan Goodyear

[Hormonal changes in fertile women with quiescent systemic lupus erythematosus] - Abstr... - 0 views

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    Abstract suggests that low progesterone plays a role in Lupus.
Nathan Goodyear

The effect of oral micronized progesterone on ... [Fertil Steril. 2010] - PubMed - NCBI - 0 views

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    The effect of oral micronized progesterone on hormonal and metabolic parameters in anovulatory patients with polycystic ovary syndrome.
Nathan Goodyear

Metabolic influences on neuroendocrine regulation of reproduction - 0 views

  • Energy storage occurs mainly at the level of white adipose tissue, where adipocytes secrete the anorexigenic adipokine leptin
  • humans and laboratory animals with leptin or insulin deficiency or resistance and/or increased ghrelin levels exhibit delayed or absent puberty and frequently display hypogonadotropic hypogonadism, which prevents fertility
  • Ghrelin suppresses pulsatile gonadotropin-releasing hormone (GnRH) release [14,15], thus serving as a signal to suppress reproduction in times of famine
  • ...4 more annotations...
  • GnRH neurons have been shown to express insulin receptor mRNA and protein [27] and are activated by insulin
  • AgRP and NPY have the opposite (orexigenic) effect, inducing food intake.
  • Neuropeptides derived from POMC/CART neurons exert a potent anorectic action, thus decreasing food intake and body weight
  • Kisspeptins (encoded by KISS1) have been identified in the last decade as the most potent secretagogues of GnRH release.
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    Good, although brief, discussion of the interaction between metabolism and hormones.  Kisspeptin is a GNRH secreatagogue "upstream".   Insulin, Leptin, and Gherlin can inhibit GNRH through resistance and low levels.  Probably a U shaped graph of optimal activity.
Nathan Goodyear

Long-term effect of ciprofloxacin on tes... [Int J Fertil Steril. 2013] - PubMed - NCBI - 0 views

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    mouse study finds that long-term cipro can lead to biochemical disruption of the testicles resulting in infertility, effected sperm counts, and decreased Testosterone.
Nathan Goodyear

The Effect of Oral Feeding of Tribulus t... [Int J Fertil Steril. 2013] - PubMed - NCBI - 0 views

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    Tribulus found to increase sex hormone production in opiate addicted male rats.  Opiates are known causes of low T in men.
Nathan Goodyear

Effects of androgen supplementation of hormone... [Fertil Steril. 2001] - PubMed - NCBI - 0 views

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    Testosterone therapy in post menopausal women appears to have adverse cardiovascular effects in women.  The negative effects were an increase in Pulsatility index and adverse change in lipid profiles.  This seemed to counter the positive effects by estrogen.  Others have proposed that combination E2 and T therapy hide the negative effects of testosterone on CV health in women.
Nathan Goodyear

The question of declining sperm density revisited: an analysis of 101 studies published... - 0 views

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    Re-analysis of Carlsen's work on sperm count finds consistent decline in sperm count.  Swan and authors found a 1.5% decline in US men from 1934-1996 and 3% annual decline in European/Australian men over same time frame.  This was a meta-analysis of 101 studies from 1934-1996.  Yes, there is geographical variation, but the overall trend is one of decline.
Nathan Goodyear

Environmental/lifestyle effects on spermatogenesis - 0 views

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    The environment is playing a role in reduced testicular function in men.
Nathan Goodyear

Journal of Endocrinological Investigation - 0 views

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    Study found that men who carry cell phones in their pants for > 4 hours have increased sperm fragmentation.  
Nathan Goodyear

High-dose vitamin D supplementation and measur... [Fertil Steril. 2014] - PubMed - NCBI - 0 views

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    No significant statistical significance was found with vitamin D therapy and insulin sensitivity.  However, improved outcomes were found in 2 hour insulin and 2 hour glucose levels after a 75 gram OGTT.
Nathan Goodyear

Subclinical hypothyroidism in young women with... [Fertil Steril. 2013] - PubMed - NCBI - 0 views

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    Link exists between PCOS and subclinical hypothyroidism.  Another term is functional hypothyroidism.
Nathan Goodyear

Validation of Blood Spot Sampling for Gonadotropins and Ovarian Hormone Levels in Repro... - 0 views

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    blood spot Estradiol, Progesterone, LH, and FSH levels shown to be comparable to plasma levels.
Nathan Goodyear

Relationship between salivary progesterone, 17-hyd... [Fertil Steril. 2001] - PubMed re... - 0 views

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    Relationship between salivary progesterone, 17-hydroxyprogesterone, and cortisol levels throughout the normal menstrual cycle of healthy postmenarcheal girls.
Nathan Goodyear

Estradiol and progesterone regulate the proliferat... [Fertil Steril. 1998] - PubMed re... - 0 views

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    Again, progesterone reduces Estradiol stimulated breast cell growth
Nathan Goodyear

Influences of percutaneous administration of estra... [Fertil Steril. 1995] - PubMed re... - 0 views

  • Increased P concentration significantly decreases the number of cycling epithelial cells.
  • CONCLUSION: Exposure to P for 10 to 13 days reduces E2-induced proliferation of normal breast epithelial cells in vivo.
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    Progesterone reduces Estradiol breast cell growth
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