Group items tagged Testosterone:estradiol - Dr. Goodyear

Aromatase and regulating the estrogen:androgen ratio in the prostate gland - 0 views

www.sciencedirect.com/...S0960076009002696

estrogen estradiol Testosterone T:E2 prostate cancer prostate BPH male men hormone hormones cancer health ER alpha ER beta aromatase activity aromatase

shared by Nathan Goodyear on 21 Aug 13 - No Cached

Nathan Goodyear on 21 Aug 13

This article summarizes it all. With age, Testosterone declines and estrogen production, through elevated aromatase activity, increases. This results in a decline in the Testosterone:estradiol ratio. This has been clearly implicated in both benign and disease states of the prostate. The evidence points to aromatase activity and estrogen in the prostate to poor prostate health. Additionally, this article points out the impact of ER alpha and ER beta on the translation of the message of Estrogen.

<div class="cArrow"> </div><div class="cContentInner">This article summarizes it all. With age, Testosterone declines and estrogen production, through elevated aromatase activity, increases. This results in a decline in the Testosterone:estradiol ratio. This has been clearly implicated in both benign and disease states of the prostate. The evidence points to aromatase activity and estrogen in the prostate to poor prostate health. Additionally, this article points out the impact of ER alpha and ER beta on the translation of the message of Estrogen.</div>

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In Men, Peripheral Estradiol Levels Directly Reflect the Action of Estrogens at the Hyp... - 0 views

jcem.endojournals.org/...3324

estrogen men low testosterone

shared by Nathan Goodyear on 14 Jan 11 - No Cached

Nathan Goodyear on 14 Jan 11

peripheral estrogen in men inhibits testosterone production and secretion

<div class="cArrow"> </div><div class="cContentInner">peripheral estrogen in men inhibits testosterone production and secretion</div>

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Associations between cadmium exposure and circulating levels of sex... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25173093

Testosterone Cadmium Estradiol menopause post menopause breast cancer women female hormone hormones

shared by Nathan Goodyear on 06 Feb 15 - No Cached

Nathan Goodyear on 06 Feb 15

Cadmium levels found to be positively associated with serum Testosterone levels in women. Cadmium inversely associated with E2 levels. Cadmium has been associated with increased breast cancer risk in women.

<div class="cArrow"> </div><div class="cContentInner">Cadmium levels found to be positively associated with serum Testosterone levels in women. Cadmium inversely associated with E2 levels. Cadmium has been associated with increased breast cancer risk in women. </div>

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Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Ath... - 0 views

www.maturitas.org/...abstract

vitamin D hormones SHBG estradiol Testosterone free Testosterone total Testosterone DHEA

shared by Nathan Goodyear on 13 Mar 17 - No Cached

Nathan Goodyear on 13 Mar 17

low vitamin D levels effect sex hormone levels in men and women.

<div class="cArrow"> </div><div class="cContentInner">low vitamin D levels effect sex hormone levels in men and women.</div>

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SpringerPlus | Full text | Testosterone-derived estradiol production by male endotheliu... - 0 views

www.springerplus.com/...214

aromatase activity aromatase estradiol estrogen atherosclerosis hormone hormones male ER-alpha ER alpha

shared by Nathan Goodyear on 04 Oct 13 - No Cached

Nathan Goodyear on 04 Oct 13

Mouse study, but aromatase activity and ER alpha required for atherosclerosis in male mice.

<div class="cArrow"> </div><div class="cContentInner">Mouse study, but aromatase activity and ER alpha required for atherosclerosis in male mice.</div>

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Informa Healthcare - Systems Biology in Reproductive Medicine - 52(2):97 - Summary - 0 views

informahealthcare.com/...01485010500315479

Testosterone Estadiol Testosterone:Estradiol ratio HPA estrogen dominance low T aromatase obesity overweight

shared by Nathan Goodyear on 10 Oct 11 - No Cached

Nathan Goodyear on 10 Oct 11

a decreasing Testosterone:Estradiol ratio leads to decreased sperm production. This effectively occurs through the interaction of the elevated Estradiol and the HPA.

<div class="cArrow"> </div><div class="cContentInner">a decreasing Testosterone:Estradiol ratio leads to decreased sperm production. This effectively occurs through the interaction of the elevated Estradiol and the HPA.</div>

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Androgen Deprivation Therapy and the Re-em... [Oncol Hematol Rev. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24932461

androgen deprivation therapy ADT estrogen Testosterone men male hormone hormones Prostate cancer CVD cardiovascular disease

shared by Nathan Goodyear on 08 Jul 14 - No Cached

Nathan Goodyear on 08 Jul 14

Sometimes I think medicine has lost its mind. Or at least, it is not thinking things through. To give IV estrogen to decrease Testosteorne in men with prostate cancer is devoid of the pathophysiology of prostate cancer and cardiovascular disease in men. Elevated Estradiol in men increases CRP, IL-1beta, and TNF-alpha to name a few cytokines. The proported purpose of the IV estrogen is to prevent the cardiovascular complications associated with ADT. Yet, elevated aromatase activity and low T in men are both shown to be associated with increased CVD in men.

<div class="cArrow"> </div><div class="cContentInner">Sometimes I think medicine has lost its mind. Or at least, it is not thinking things through. To give IV estrogen to decrease Testosteorne in men with prostate cancer is devoid of the pathophysiology of prostate cancer and cardiovascular disease in men. Elevated Estradiol in men increases CRP, IL-1beta, and TNF-alpha to name a few cytokines. The proported purpose of the IV estrogen is to prevent the cardiovascular complications associated with ADT. Yet, elevated aromatase activity and low T in men are both shown to be associated with increased CVD in men.</div>

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Androgen insufficiency in women: diagnostic and therapeutic implications - 0 views

humupd.oxfordjournals.org/...421.full

SHBG androgen testosterone androgens DHT women insufficiency deficiency

shared by Nathan Goodyear on 12 Jun 13 - No Cached

SHBG has a differing binding affinity for sex steroids in the following order; DHT > testosterone > androstenedione > estradiol > estrone
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SHBG also weakly binds DHEA, but not DHEAS
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Nathan Goodyear on 12 Jun 13

Good discuss of androgen deficiency in women. Also, good discussion of SHBG.

<div class="cArrow"> </div><div class="cContentInner">Good discuss of androgen deficiency in women. Also, good discussion of SHBG. </div>

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The heritability of circulating testosterone, oestradiol, oestrone and sex hormone bind... - 0 views

www.medaus.com/2111

Testosterone Estradiol Estrogen genetics genetic hormone hormones men male

shared by Nathan Goodyear on 16 Jan 14 - No Cached

Nathan Goodyear on 16 Jan 14

No surprise here as genetics and environment play in a role in all disease. Here it is hormones.

<div class="cArrow"> </div><div class="cContentInner">No surprise here as genetics and environment play in a role in all disease. Here it is hormones. </div>

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Endocrine milieu and erectile dysfunction: is oestradiol-testosterone imbalance, a risk... - 0 views

www.ncbi.nlm.nih.gov/...PMC3739617

erectile dysfunction ED low T Testosterone T:E2 Estradiol men male hormone hormones

shared by Nathan Goodyear on 05 Feb 14 - No Cached

Nathan Goodyear on 05 Feb 14

This article points to the impact of T:E2 on ED in men. A declining T:E2 increases ED in older men.

<div class="cArrow"> </div><div class="cContentInner">This article points to the impact of T:E2 on ED in men. A declining T:E2 increases ED in older men. </div>

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Aromatase Explains Why Testosterone Increases Breast Cancer Rate - 0 views

cebp.aacrjournals.org/...1942.full

Testosterone aromatase estradiol breast cancer women female hormones hormone

shared by Nathan Goodyear on 20 Mar 14 - No Cached

Thieme E-Journals - Hormone and Metabolic Research / Abstract - 0 views

www.thieme-connect.com/...DOI

hormone hormones estradiol pancreatic cancer

shared by Nathan Goodyear on 17 Sep 13 - No Cached

Nathan Goodyear on 17 Sep 13

small study, but males with pancreatic cancer were found to have higher levels of FSH (p < 0.01), LH and oestradiol (p < 0.001) and lower levels of progesterone (p < 0.01) and testosterone (p < 0.05) than the controls. Female patients with pancreatic cancer were found to have higher levels of oestradiol (p < 0.001) and lower levels of LH, FSH and progesterone. Though cause and effect is not known, the expression of ER alpha in pancreatic cancer is known and the inflammatory and pro-growth signal of ER alpha is known, thus heavy stimulation would be unwise.

<div class="cArrow"> </div><div class="cContentInner">small study, but males with pancreatic cancer were found to have higher levels of FSH (p < 0.01), LH and oestradiol (p < 0.001) and lower levels of progesterone (p < 0.01) and testosterone (p < 0.05) than the controls. Female patients with pancreatic cancer were found to have higher levels of oestradiol (p < 0.001) and lower levels of LH, FSH and progesterone. Though cause and effect is not known, the expression of ER alpha in pancreatic cancer is known and the inflammatory and pro-growth signal of ER alpha is known, thus heavy stimulation would be unwise.</div>

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Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses - 0 views

www.ncbi.nlm.nih.gov/...PMC3351364

hormone hormones saliva salivary testing estrone estradiol estriol progesterone testosterone natural

shared by Nathan Goodyear on 15 Oct 12 - No Cached

Nathan Goodyear on 15 Oct 12

recent study proves the scientific validity of sex hormone evaluation via saliva. Most labs today use ELIZA. The new future will be mass spectroscopy.

<div class="cArrow"> </div><div class="cContentInner">recent study proves the scientific validity of sex hormone evaluation via saliva. Most labs today use ELIZA. The new future will be mass spectroscopy.</div>

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Longitudinal Study of Hormonal and P... [J Clin Endocrinol Metab. 2013] - PubMed - NCBI - 1 views

www.ncbi.nlm.nih.gov/...23430788

saliva salivary hormone hormones urine estradiol testosterone

shared by Nathan Goodyear on 27 Feb 13 - No Cached

Nathan Goodyear on 27 Feb 13

salivary and urine testing used to assess sex hormone levels in young twins.

<div class="cArrow"> </div><div class="cContentInner">salivary and urine testing used to assess sex hormone levels in young twins. </div>

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Sex Steroid Hormone Levels and Body Composition in Men - 0 views

jcem.endojournals.org/...2442.abstract

hormone body composition hormones body composition Testosterone Estradiol E2 T SHBG

shared by Nathan Goodyear on 10 Jun 13 - No Cached

Nathan Goodyear on 10 Jun 13

The results of this study: body composition i.e. fat, effects hormone levels, rather then hormone effecting body composition.

<div class="cArrow"> </div><div class="cContentInner">The results of this study: body composition i.e. fat, effects hormone levels, rather then hormone effecting body composition. </div>

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Chewing gum has large effects on salivary testosterone, estradiol, and secretory immuno... - 0 views

141.213.232.243/...chewing_gum.pdf

saliva salivary gum testing

shared by Nathan Goodyear on 30 Oct 12 - No Cached

Nathan Goodyear on 30 Oct 12

Don't chew gum to increase saliva for saliva testing.

<div class="cArrow"> </div><div class="cContentInner">Don't chew gum to increase saliva for saliva testing.</div>

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Aromatase Inhibition in the Human Male Reveals a Hypothalamic Site of Estrogen Feedback - 0 views

jcem.endojournals.org/...3027.long

estrogen estradiol estrone testosterone low T HPA hypothalamus pituitary male

shared by Nathan Goodyear on 25 Apr 12 - No Cached

Nathan Goodyear on 25 Apr 12

estrogen shown to have two sites of negative feedback in men. First in the hypothalamus and second in the pituitary. In many men, aromatase inhibition can restore the HPA by eliminating the negative feedback of estrogen on the hypothalamus and the pituitary.

<div class="cArrow"> </div><div class="cContentInner">estrogen shown to have two sites of negative feedback in men. First in the hypothalamus and second in the pituitary. In many men, aromatase inhibition can restore the HPA by eliminating the negative feedback of estrogen on the hypothalamus and the pituitary.</div>

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Inflammation and prostate cancer, Future Oncology, Future Medicine - 0 views

www.futuremedicine.com/...14796694.4.5.637

inflammation testosterone estradiol E2 T:E2 prostate cancer prostatitis

shared by Nathan Goodyear on 01 May 12 - No Cached

Nathan Goodyear on 01 May 12

low T:E2 ratio increases inflammation in prostate. This has implications in prostatitis and prostate cancer.

<div class="cArrow"> </div><div class="cContentInner">low T:E2 ratio increases inflammation in prostate. This has implications in prostatitis and prostate cancer.</div>

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Endogenous Sex Hormones and Prostate Cancer: A Collaborative Analysis of 18 Prospective... - 0 views

jnci.oxfordjournals.org/...170.long

hormones prostate cancer hormone sex hormones testosterone DHT estradiol men

shared by Nathan Goodyear on 05 Jul 12 - No Cached

Nathan Goodyear on 05 Jul 12

a large collaborative analysis finds no association between ANY sex hormones and prostate cancer.

<div class="cArrow"> </div><div class="cContentInner">a large collaborative analysis finds no association between ANY sex hormones and prostate cancer. </div>

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ScienceDirect - Pathologie Biologie : Saliva assays in clinical and research biology - 0 views

www.sciencedirect.com/...S0369811401002280

saliva salivary stress sex hormones cortisol estradiol estriol progesterone testosterone testing evaluation BHRT

shared by Nathan Goodyear on 26 Nov 11 - No Cached

the saliva concentration reflects the free blood concentration.
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Nathan Goodyear on 26 Nov 11

saliva testing of stress and sex hormones have been utilized since the early 1980's and described as "well validated" in the literature.

<div class="cArrow"> </div><div class="cContentInner">saliva testing of stress and sex hormones have been utilized since the early 1980's and described as "well validated" in the literature.</div>

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