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Nathan Goodyear

Serum LBP Is Associated with Insulin Resistance in Women with PCOS - 0 views

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    increased LBP associated with PCOS through insulin resistance.
Nathan Goodyear

Age and BMI Adjusted Comparison of Reproductive Hormones in PCOS - 0 views

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    study of Saudi women with PCOS finds elevated LH/FSH ratio and elevated total Testosterone levels independent of age and weight; in addition, lower FSH, SHBG, and progesterone levels we found.
Nathan Goodyear

Inflammation in Response to Glucose Ingestion Is Independent of Excess Abdominal Adipos... - 0 views

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    women with PCOS, inflammatory cytokines TNF-alpha and CRP, associated with increasing androgen levels and with abdominal fat.  Women with less fat had lower levels of TNF-alpha and CRP than their higher weight counterparts, though the inflammatory cytokines were still evident.
Nathan Goodyear

CIRCULATING INFLAMMATORY MARKERS IN POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW AND ... - 0 views

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    It is well known that obesity increases CRP.  However, in this meta-analysis, CRP elevation in women with PCOS was found to be independent from obesity and as they concluded: "...chronic low-grade inflammation that may underpin the pathogenesis of this disorder".
Nathan Goodyear

High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome - 0 views

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    Increased rate of autoimmune thyroid disease found in women with the hormonal imbalances found in PCOS.  
Nathan Goodyear

Effects of androgens on insulin actio... [Diabetes Metab Res Rev. 2008] - PubMed - NCBI - 0 views

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    elevated insulin associated with insulin resistance causes elevated male hormones in women.  Whether it is in PCOS or postmenopausal over-aggressive replacement, Testosterone also turns right around and contributes to insulin resistance.  Vicious cycle.
Nathan Goodyear

Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placeb... - 0 views

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    Only abstract available.  Resveratrol found to reduce total Testosterone by 23% and DHEAS by 22% in women with PCOS;  a decrease in insulin by 32% and improved insulin sensitivity was also noted.
Nathan Goodyear

Biomedical Papers: The prevalence of non organ specific and thyroid autoimmunity in pat... - 0 views

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    high prevalence of thyroid antibodies, TPO, in women with PCOS.  This does not prove cause and effect, merely an association.  Both are inflammation driven.
Nathan Goodyear

High prevalence of chronic thyroiditis in patients with polycystic ovary syndrome. - Pu... - 0 views

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    Autoimmune thyroid present in 1/3 of women with PCOS.
Nathan Goodyear

Polycystic Ovary Syndrome May Be an Autoimmune Disorder - 0 views

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    Article proposes that PCOS may be autoimmune.  Clearly it is inflammatory.
Nathan Goodyear

Metabolic and Endocrine Effects of a Polyunsaturated Fatty Acid-Rich Diet in Polycystic... - 0 views

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    polyunsaturated fats found to improve PCOS
Nathan Goodyear

Altered Cortisol Metabolism in Polycystic Ovary Syndrome: Insulin Enhances 5α... - 0 views

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    lean women with PCOS found to have reduced 11 beta-HSD1 and increased 5 alpha reductase activity.  This, in part, is associated with the elevated cortisol and androgens in these women.
Nathan Goodyear

Low Grade Chronic Inflammation in Women with Polycystic Ovarian Syndrome - 0 views

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    Women with PCOS have associated increased inflammation.  This origin is primarily via adipose tissue and associate adipocytokines (TNF-alpha, and IL-6).  CRP elevation, as found in this study, is associated with increased CVD.
Nathan Goodyear

Uncoupling between insulin and rele... [Metab Syndr Relat Disord. 2010] - PubMed - NCBI - 0 views

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    Obese women with PCOS found to have uncoupled insulin and d-chiro-inositol secretion thus worsening insulin resistance
Nathan Goodyear

Effects of Chinese Green Tea on Weight, and Hormonal and Biochemical Profiles in Obese ... - 0 views

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    green tea not shown improve weight loss in obese chinese women with PCOS.  Study doesn't identify the type of green tea.  There are many types and qualities of green teas.
Nathan Goodyear

Low circulating adiponectin levels in women with... [Tumour Biol. 2014] - PubMed - NCBI - 0 views

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    low adiponectin levels associated with PCOS in women.  
Nathan Goodyear

Glucose and lipopolysaccharide regulate pro... [J Reprod Immunol. 2014] - PubMed - NCBI - 0 views

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    elevated androgens (male hormones) correlated with low grade inflammation and atherogenesis in women with PCOS.  This was found more in those women that were obese.
Nathan Goodyear

Sex hormone binding globulin, but not testosterone, is associated with the metabolic sy... - 0 views

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    This study finds an association between low SHBG and increased metabolic syndrome in obese women with PCOS.  Testosterone was not associated.  Other studies have shown a positive association between Testosterone and MetS in women.  This follows men in that SHBG shows an association with MetS.  Only the abstract is present here, so I can't look at the data presented.
Nathan Goodyear

Analysis of the vascular responses in a murine model of polycystic ovary syndrome - 0 views

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    Animal model of PCOS provides insight to changes in vascular response.  In this animal mode, DHT resulted in a decrease in vasorelaxation of arterial endothelium.
Nathan Goodyear

Obstructive Sleep Apnea Predisposes to Nonalcoh... [Endocr Pract. 2013] - PubMed - NCBI - 0 views

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    sleep apnea in women with PCOS found to be associated with NAFLD. The free Testosterone was directly associated with sleep apnea.
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