neuroinflammaiton, also described as excitotoxicity, found in the brains of children/young adults that lived in high air pollution areas. Neuroinflammation (IL-6, IL-1, TNF-alpha, IFN-gamma...) found in the brains of these children and young adults. This is the same process found in Alzheimers and other excitotoxicity disease states. Addtionally, it is also involved in most chronic diseases of aging.
Awesome review article on TA-1 and its broad immunomodulatory effects, i.e. increase IL-1, IFN-gamma, increase dendritic cell activity, inhibition of tumor growth…