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Nathan Goodyear

Interferon-[alpha] reduces the density of monoaminergic axon... : NeuroReport - 0 views

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    inflammation, IFN-gamma, shown to lead to 5-HT and noradrenergic axon degeneration.  This reveals another inflammatory contribution to depression
Nathan Goodyear

The endocrinology of sexual arousal - 0 views

  • A number of age-related changes may be relevant: altered negative feedback of testosterone and hence less increase in luteinizing hormone (LH) with falling testosterone levels, increased sex hormone binding globulin (SHBG) and hence relatively reduced free testosterone and the likelihood of an age-related decline in testosterone receptor sensitivity
  • In the older male, the picture is complicated by various aging effects, including altered hypothalamo–pituitary feedback, increased testosterone binding and reduced receptor sensitivity
  • The neurophysiological basis of NPT is still disputed, but one plausible explanation is that REM sleep is associated with a ‘switching off’ of the noradrenergic cells in the locus coeruleus
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  • the impact of testosterone on the emergence of sexual arousability is less clear
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    Good discussion of the arousal/sexual response differences between men and women from a physiological perspective.  
Nathan Goodyear

Effects of Hypo- and Hyperthyroidism on Noradrenergic Activity and Glycerol Concentrati... - 0 views

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    Thyroid hormone increased localized norepinephrine production and liposlys resulting in decreases SQ adipose tissue compared to hypothyroid.  This study showed a localized effect of adipose tissue by thyroid hormone. 
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