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Nathan Goodyear

Reduced intravenous glutathione in the treatment o... [Prog Neuropsychopharmacol Biol P... - 0 views

www.ncbi.nlm.nih.gov/...8938817

glutathione Parkinson's Disease

shared by Nathan Goodyear on 28 Jun 11 - No Cached
  • Nathan Goodyear on 28 Jun 11
     
    glutathione benefits Parkinson's disease patients
Nathan Goodyear

Antiinflammatory Effects of Estrogen on Microglial Activation - 0 views

endo.endojournals.org/...3646.long

Estradiol E2 neurodegenerative disease Parkinsons's Alzheimer's inflammation microglial glial cells hormones hormone estrogen

shared by Nathan Goodyear on 07 Jun 12 - No Cached
  • Nathan Goodyear on 07 Jun 12
     
    Estradiol (E2) shown to be neuroprotective in those with microglial excitotoxicity diseases, such as Parkinson's and Alzheimer's disease.  this study looked at a rat model.  The effect was not through inhibition of NF-kappaB, but through MAP kinase.
Nathan Goodyear

ScienceDirect.com - Physiology & Behavior - Mitochondrial complex I inhibition depletes... - 0 views

www.sciencedirect.com/...S0031938404003403

testosterone mitochondria parkinson's disease Parkinson's

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone is known to provide anti-inflammatory signaling in men.  This study, inhibition of mitochondrial complex I (coQ dependent) resulted in lower testosterone in rat models.  One of the major side effects of statin therapy is poor memory and brain fog. Hmmm.
Nathan Goodyear

NRF2 activation restores disease related metabolic ... [PLoS One. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21747966

NRF2 Parkinson's disease neurodegenerative disorders

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    NRF2 could be a new target of therapy for people with Parkinson's and other neurodegenerative disorders.
Nathan Goodyear

Rationale for the Successful Management of EDTA Chelation Therapy in Human Burden by To... - 0 views

www.ncbi.nlm.nih.gov/...PMC5118545

chelation heavy metals Pb Hg Al lead mercury aluminum cadmium Cd EDTA CVD cardiovascular disease Parkinson's disease Alzheimer's disease MS multiple Sclerosis ALS

shared by Nathan Goodyear on 06 Mar 18 - No Cached
  • Nathan Goodyear on 06 Mar 18
     
    Good recent review of chelation.  Briefly discusses the benefit of chelation with cardiovascular disease and neurodegenerative diseases.
Nathan Goodyear

Nicotine from edible Solanaceae and risk of Parkinson disease - Nielsen - 2013 - Annals... - 0 views

onlinelibrary.wiley.com/...5BC47A800DBC9C1E382613A.d04t03

nicotine peppers Solanaceae Parkinson's disease Parkinson's neurology

shared by Nathan Goodyear on 01 Jun 13 - No Cached
  • Nathan Goodyear on 01 Jun 13
     
    Nicotine from plants like peppers found to be associated with reduced incidence of Parkinsons disease.
Nathan Goodyear

High doses of vitamin E in the treatment of disorders of the central nervous system in ... - 0 views

ajcn.nutrition.org/...793.full

vitamin E Parkinson's disease Parkinson's alzheimer's disease Alzheimers alternative medicine

shared by Nathan Goodyear on 13 Jun 16 - No Cached
  • Nathan Goodyear on 13 Jun 16
     
    High dose vitamin E, in doses up to 2,000 IU, in patients with Parkinson, Alzheimers and tar dive dyskinesia found to be safe and somewhat effective in these disease states in older individuals.  The length of the studies reviewed were up to 2 years.
Nathan Goodyear

LRRK2 G2019S Impairs Chaperone-Mediated Autophagy in Neurons (S13.003) -- Kuo et al. 80... - 0 views

www.neurology.org/...S13.003

Parkinsons disease neurology Lewy Bodies Chaperone-mediated autophagy

shared by Nathan Goodyear on 01 Jun 13 - No Cached
  • Nathan Goodyear on 01 Jun 13
     
    impaired auto destruction process leads to the Lewy bodies found in Parkinson's disease.
Nathan Goodyear

Amino acid management of Parkinson's disease: a case study - 0 views

www.ncbi.nlm.nih.gov/...PMC3068871

Parkinson's disease Parkinson's disease amino acids natural

shared by Nathan Goodyear on 18 May 15 - No Cached
  • Nathan Goodyear on 18 May 15
     
    to be read
Nathan Goodyear

Neuroprotective and disease-modifying effects of the ketogenic diet - 0 views

www.ncbi.nlm.nih.gov/...PMC2367001

ketogenic diet nutrition diet CNS brain Epilepsy alzheimer's disease Parkinson's disease

shared by Nathan Goodyear on 20 Feb 16 - No Cached
  • Nathan Goodyear on 20 Feb 16
     
    great review of the ketogenic diet in neuroprotective and treatment of excitotoxic disease.
Nathan Goodyear

JAMA Network | JAMA Neurology | Beneficial Effects of Testosterone Replacement for the ... - 0 views

archneur.jamanetwork.com/article.aspx

testosterone therapy treatment Parkinson's parkinson's disease non motor symptoms neurology

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone shown to provide benefit for non motor Parkinson symptoms.
Nathan Goodyear

Progesterone exerts neuroprotective effects after brain injury 10.1016/j.brainresrev.20... - 0 views

www.sciencedirect.com/...S0165017307001129

progesterone CNS bioidentical hormone hormones natural

shared by Nathan Goodyear on 19 Jan 12 - No Cached
  • Nathan Goodyear on 19 Jan 12
     
    progesterone shown to have neuroprotective and  healing properties in the CNS.  This has implications in Stroke, and possibly even excitotoxic disease such as Parkinson's, Alzhemier's...
Nathan Goodyear

Investigations on oxidativ... [Eur Arch Psychiatry Clin Neurosci. 1999] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10654103

AGE advanced glycation end products neurodegenerative disease free radicals Alzheimer's Parkinson's disease antioxidants inflammation

shared by Nathan Goodyear on 13 Jun 12 - No Cached
  • Nathan Goodyear on 13 Jun 12
     
    This study finds that AGE, advanced glycation end products, play a significant role in free radical generation and neurodegenerative disease. Quote: "... pharmacologoical approaches which break the vicious cycle of oxidative stress and neurodegeneration offer new opportunities for the treatment of AD. These approaches include AGE- inhibitors, antioxidants, and anti-inflammatory substances which prevent radical production." They focus on the pharmacological, how about the natural first?
Nathan Goodyear

Mitochondrial dysfunction and oxidative damage in ... [J Bioenerg Biomembr. 2004] - Pub... - 0 views

www.ncbi.nlm.nih.gov/...15377876

mitochondrial dysfunction CoQ10 neurodegenerative diseases

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • he increasing evidence that Parkinson's disease is associated with abnormalities in the electron transport gene as well as oxidative damage
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 useful to improve mitochondrial function and thus treatment of neurodegenerative diseases
Nathan Goodyear

Phase IIb Study of Intranasal Glutathione in Parkinson's Disease - 0 views

www.ncbi.nlm.nih.gov/...PMC5438472

glutathione Parkinson's disease

shared by Nathan Goodyear on 06 Mar 18 - No Cached
  • Nathan Goodyear on 06 Mar 18
     
    Study suggests improvement in Parksinons disease with intranasal glutathione.
Nathan Goodyear

Mitochondria, metabolic disturbances, oxidative st... [J Neurol Sci. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17462670

mitochondria Coq10 kynurenine neurodegenerative disease Parkinson's Alzheimer's Huntington's

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • Nathan Goodyear on 07 Feb 11
     
    Great article on CoQ10, mitochondrial function, the kynurenine system and neurodegenerative diseases
Nathan Goodyear

Oxidative stress and neurotoxicity. [Chem Res Toxicol. 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18052107

oxidative stress mitochondria neurodegenerative disease Parkinson's Alzheimer's Huntington's ALS MS

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • Nathan Goodyear on 07 Feb 11
     
    Great article on how oxidative stress, and thus mitochondrial dysfunction, are at the core of neurodegenerative diseases
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...18463003

mitochondria aging neurodegenerative disease Alzheimer's Parkinson's Huntington's ALS

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • Nathan Goodyear on 07 Feb 11
     
    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

SpringerLink - NeuroMolecular Medicine, Volume 10, Number 4 - 0 views

www.springerlink.com/...8r1310q48u375037

mitochondria aging disease neurodegenerative Parkinson's Alzheimer's MS Huntington's

shared by Nathan Goodyear on 07 Mar 11 - No Cached
  • Nathan Goodyear on 07 Mar 11
     
    nice discussion of mitochondria and their implication in aging and neurodegenerative disease
Nathan Goodyear

Glutamate and the glutamate receptor system: a tar... [Int J Geriatr Psychiatry. 2003] ... - 0 views

www.ncbi.nlm.nih.gov/...12973748

glutamate glutamic acid excitotoxicity Parkinson's MS Alzheimer's Huntington's disease neurodegenerative

shared by Nathan Goodyear on 18 Mar 11 - No Cached
  • Under certain conditions, glutamate has a toxic action resulting from an activation of specific glutamate receptors, which leads to acute or chronic death of nerve cells.
  • Nathan Goodyear on 18 Mar 11
     
    deep, heavy read on glutamate excitotoxicity and neuronal death leading to neurodegenerative disease
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