Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994.
Parekh N, Chappell RJ, Millen AE, Albert DM, Mares JA.
Arch Ophthalmol. 2007 May;125(5):661-9.
PMID: 17502506
Geographical differences in vitamin D status, with particular reference to European countries
Lars Ovesen*, Rikke Andersen and Jette Jakobsen
Institute of Food Safety and Nutrition, The Danish Veterinary and Food Administration, 30A Sydmarken, 2860 S
According to a recent study in the Archives of Internal Medicine, 75 percent of Americans do not get enough Vitamin D. Researchers have found that the deficiency may negatively impact immune function and cardiovascular health and increase cancer risk. Now, a University of Missouri nutritional sciences researcher has found that vitamin D deficiency is associated with inflammation, a negative response of the immune system, in healthy women.
Vitamin D status predicts physical performance and its decline in older persons.
Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P.
J Clin Endocrinol Metab. 2007 Jun;92(6):2058-65. Epub 2007 Mar 6.
PMID: 17341569
doi:10.1210/jc.2006-1525
ONCLUSIONS: Serum 25-OHD concentrations below 20 ng/ml are associated with poorer physical performance and a greater decline in physical performance in older men and women. Because almost 50% of the population had serum 25-OHD below 20 ng/ml, public health strategies should be aimed at this group.
Vitamin D and pancreatic cancer risk in the alpha-tocopherol, beta-carotene cancer prevention cohort.
Michaud DS.
Cancer Res. 2006 Oct 15;66(20):9802-3.
Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2.
Chan J, Jaceldo-Siegl K, Fraser GE.
Am J Clin Nutr. 2009 May;89(5):1686S-1692S. Epub 2009 Apr 1.
PMID: 19339396
Conclusions: s25(OH)D concentrations were not associated with vegetarian status. Other factors, such as vitamin D supplementation, degree of skin pigmentation, and amount and intensity of sun exposure have greater influence on s25(OH)D than does diet.
Differences in vitamin D status between countries in young adults and the elderly.
McKenna MJ.
Am J Med. 1992 Jul;93(1):69-77.
PMID: 1385673
PURPOSE: To compare vitamin D status between countries in young adults and in the elderly. MATERIALS AND METHODS: Reports on vitamin D status (as assessed by serum 25-hydroxyvitamin D) from 1971 to 1990 were reviewed. Studies were grouped according to geographic regions: North America (including Canada and the United States); Scandinavia (including Denmark, Finland, Norway, and Sweden); and Central and Western Europe (including Belgium, France, Germany, Ireland, The Netherlands, Switzerland, and the United Kingdom). RESULTS: Vitamin D status varies with the season in young adults and in the elderly, and is lower during the winter in Europe than in both North America and Scandinavia. Oral vitamin D intake is lower in Europe than in both North America and Scandinavia. Hypovitaminosis D and related abnormalities in bone chemistry are most common in elderly residents in Europe but are reported in all elderly populations. CONCLUSIONS: The vitamin D status in young adults and the elderly varies widely with the country of residence. Adequate exposure to summer sunlight is the essential means to ample supply, but oral intake augmented by both fortification and supplementation is necessary to maintain baseline stores. All countries should adopt a fortification policy. It seems likely that the elderly would benefit additionally from a daily supplement of 10 micrograms of vitamin D.
Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women.
Peterson CA, Heffernan ME.
J Inflamm (Lond). 2008 Jul 24;5:10.
PMID: 18652680
doi:10.1186/1476-9255-5-10
Conclusion
Serum 25(OH)D status is inversely related to TNF-α concentrations in healthy women, which may in part explain this vitamin's role in the prevention and treatment of inflammatory diseases. Results gleaned from this investigation also support the need to re-examine the biological basis for determining optimal vitamin D status.
Pittas AG, Harris SS, Stark PC, Dawson-Hughes B.
The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adults.
Diabetes Care. 2007 Apr;30(4):980-6. Epub 2007 Feb 2.
PMID: 17277040 [PubMed - in
Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P.
Vitamin D status predicts physical performance and its decline in older persons.
J Clin Endocrinol Metab. 2007 Jun;92(6):2058-65. Epub 2007 Mar 6.
PMID: 17341569 [PubMed