Group items matching

in title, tags, annotations or url

"November 26, 2008 New evidence may explain why it is that we lose not only our youthful looks, but also our youthful pattern of gene activity with age. A report in the November 26th issue of the journal Cell, a Cell Press publication, reveals that a protein perhaps best known for its role in the life-extending benefits of a low-calorie diet also maintains the stability of the mammalian genome-the complete set of genetic instructions "written" in DNA. The researchers found in studies of mammalian stem cells that the protein SIRT1 controls the packaging of DNA into chromatin, thereby setting the youthful pattern of gene activity by keeping select genes switched off. In response to DNA damage, those SIRT1 proteins leave their posts to go off and assist in the necessary repairs. That change in SIRT1's job description leads to shifts in gene activity that parallel those seen in the aging mouse brain, they show. They suspect similar changes would also be found in other body tissues as well."

Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology. Pedrini S, Thomas C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, Martins RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S. Mol Neurodegener. 2009 Oct 21;4:40. PMID: 19845940 doi:10.1186/1750-1326-4-40 INTERPRETATION: Dissociation of Abeta changes from brain mass changes raises the possibility that diet plays a role not only in modulating amyloidosis but also in modulating neuronal vulnerability. However, in the absence of a study of the effects of a high protein/low carbohydrate diet on nontransgenic mice, one cannot be certain how much, if any, of the loss of brain mass exhibited by high protein/low carbohydrate diet-fed TgCRND8 mice was due to an interaction between cerebral amyloidosis and diet. Given the recent evidence that certain factors favor the maintenance of cognitive function in the face of substantial structural neuropathology, we propose that there might also exist factors that sensitize brain neurons to some forms of neurotoxicity, including, perhaps, amyloid neurotoxicity. Identification of these factors could help reconcile the poor clinicopathological correlation between cognitive status and structural neuropathology, including amyloid pathology.

The effect of select nutrients on serum high-density lipoprotein cholesterol and apolipoprotein A-I levels. Mooradian AD, Haas MJ, Wong NC. Endocr Rev. 2006 Feb;27(1):2-16. Epub 2005 Oct 21. Review. PMID: 16243964 One of the factors contributing to the increased risk of developing premature atherosclerosis is low plasma concentrations of high-density lipoprotein (HDL) cholesterol (HDLc). Multiple potential mechanisms account for the cardioprotective effects of HDL and its main protein apolipoprotein A-I (apo A-I). The low plasma concentrations of HDL could be the result of increased fractional clearance and reduced expression of apo A-I. To this end, nutrients play an important role in modulating the fractional clearance rate, as well as the rate of apo A-I gene expression. Because medical nutrition therapy constitutes the cornerstone of management of dyslipidemias, it is essential to understand the mechanisms underlying the changes in HDL level in response to alterations in dietary intake. In this review, we will discuss the effect of select nutrients on serum HDLc and apo A-I levels. Specifically, we will review the literature on the effect of carbohydrates, fatty acids, and ketones, as well as some of the nutrient-related metabolites, such as glucosamine and the prostanoids, on apo A-I gene expression. Because there are multiple mechanisms involved in the regulation of serum HDLc levels, changes in gene transcription do not necessarily correlate with clinical observations on serum levels of HDLc.

"While research in lectinology is in its infancy this information is critical to your health and it is important to begin to understand lectins NOW. Read the following report carefully. I'll get specific about how this all applies to you. ALL foods contain lectins. Some are your friends, others neutral, and others may be your enemies. Know your lectins. Avoid your enemies. DEFINITION Protein or glycoprotein substances, usually of plant origin, of non-immunoglobulin nature, capable of specific recognition of and reversible binding to, carbohydrate moieties of complex glycoconjugates without altering the covalent structure of any of the recognized glycosyl ligands. This group includes monovalent lectins (i.e. bacterial and plant toxins). These lectins bind to sugar moieties in cell walls or membranes and thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell. (agglutination- clumping; mitosis-multiplication or division of a cell forming two daughter cells) High levels of lectins (specialized proteins) may be found in grains (also known as cereals or pulses), legumes (that is 'beans' including peanuts), dairy and plants in the nightshade family. Many other foods contain lectins but are less well studied and the amounts of lectins present are not thought to be as high or as potentially toxic.!

Vitamin D-Related Changes in Physical Performance: A Systematic Review. Annweiler C, Schott AM, Berrut G, Fantino B, Beauchet O. J Nutr Health Aging. 2009;13(10):893-898. PMID: 19924350 Conclusions: The findings show that the association between vitamin D and physical performance remains controversial. Observational studies and clinical trials yielded divergent results, which highlights the complex and to date still poorly understood association between serum vitamin D concentration or vitamin D supplementation and physical performance.

Can lifestyle changes reverse coronary heart disease? The Lifestyle Heart Trial. Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, McLanahan SM, Kirkeeide RL, Brand RJ, Gould KL. Lancet. 1990 Jul 21;336(8708):129-33. PMID: 1973470

Recent Hearing aid Accessories include wireless hearing aids. One hearing aid can transmit to the other side so that pressing one aid's program button simultaneously changes the other aid and both aids change background settings simultaneously.

Health Tips- Top 21 That will Change your Life Drastically. | Cute Girl

Neotonics Only $49/Bottle Limited Time Offer! Neotonics Special Deal + Special 51% Discount Save $300 + 60 Days Money Back Guarantee Neotonics FDA Five Star Neotonics™ is a dietary supplement specifically designed to provide essential probiotics, which are known to promote youthful, glowing skin while reducing the appearance of wrinkles. Regular Price: $99/per bottle Only for: $49/per bottle Buy Now Support Healthy Eyesight No Matter Your Age 100% NATURAL 100% NATURAL with ingredients sourced from local growers that let plants naturally reach their full maturity and use no chemical treatments 100% EFFECTIVE 100% EFFECTIVE mixing ingredients in the right way and in the right amount to keep their properties intact 100% SAFE 100% SAFE processed under strict sterile standards with regularly disinfected equipment. What Is Neotonics? NeoTonics is an all-natural supplement formulated with strains that promote skin and digestive health. Notably, the combined ingredients are reckoned to foster dermal balance, support digestion, and, thus, ensure a healthy weight. Neotonics Gummies is an all-new supplement created to enhance the health and well-being of your skin. The formula is based on research that suggests gut health plays an important role in maintaining healthy skin. This is why the Neotonics supplement boosts both gut health and skin health by using a combination of amazing nutrients. These transform the gut health and restore its functions effectively. Available as a gummy, Neotonics delivers a blend of crucial probiotics and other complementary ingredients to promote skin health, digestion, weighty loss, and more. Just take one gummy daily to support active effects. The creators of Neotonics developed the gummy based on new scientific discoveries from May 2023. That discovery revealed the root cause of skin cell turnover: an aging gut. Your gut dictates the cellular turnover rate, and gut health can promote skin health. Neotonics is

Cardio Defend™ Only $49/bottle - Limited Time Offer Flat Sale ONLY For Today - Special Offer Save Upto $120 + Special 71% Discount + 180 Day Money Back Guarantee CardioDefend Cardio Defend Rated FDA Approved CardioDefend Rated 5 Star Order TODAY And Save Up To $120! Save Over 71%! Cardio Defend is a dietary supplement that supports a healthy heart naturally. The lifestyle of individuals has evolved drastically, and with this evolution, mankind has seen a rise in individuals suffering from heart-related diseases. It supports healthy blood circulation and reduces blood pressure & the risk of heart disease naturally. Try CardioDefend For Over 71% OFF Today! Regular Price: $147.99/per bottle Only for: $49/per bottle Buy Cardio Defend Proven By Thousands Shannon Curry Mark Angelman Robert S Why Choose Cardio Defend? Made In The USA Made In The USA CardioDefend is manufactured on US soil. Cardio Defend 100% All Natural 100% All Natural All ingredients are pure, natural, and carefully sourced. FDA Approved Facility FDA Approved Facility CardioDefend is manufactured according to the latest standards. CardioDefend Supplement Cardio Defend Facts What is Cardio Defend? Heart disease is one of the top causes of death in the United States, but consumers continue to forgo the nourishment that they need. Even with all of the opportunities to eat better and exercise more, some people still struggle to improve their blood circulation and improve their heart health. Luckily, formulas like Cardio Defend can help a lot. CardioDefend is a dietary supplement that supports a healthy heart naturally. The lifestyle of individuals has evolved drastically, and with this evolution, mankind has seen a rise in individuals suffering from heart-related diseases. Even though exercise and healthy diets may help to reduce the risk of these conditions, they may not be 100% effective. The heart is an extremely important organ and must be taken good care of. CardioDefend naturally supports healt

FitSpresso Only $39/Bottle Limited Time Offer! FitSpresso Special Deal + Special 51% Discount Save $660 + 60 Days Money Back Guarantee FitSpresso Herpesyl Five Star FitSpresso is a supplement made to help people lose weight naturally. This supplement comes in the form of veggie capsules, and it is designed to boost metabolism, promote weight loss, burn fat, slow down weight gain, and destroy fat cells. Regular Price: 149/per bottle Only for: $39/per bottle Buy Now What Is FitSpresso? FitSpresso is promoted as a natural supplement that comes in the form of diet pills, and it can aid in rapid and efficient weight loss, similar to many other supplements. The term "natural supplements refers to a nutritional supplement that is made entirely of natural, chemical-free materials. You can utilize these organic ingredients to aid in natural weight loss. It can speed up your body's metabolism and assist with other crucial processes. All parts of our bodies are impacted by weight increase, and not only do we need to deal with the increased weight, but we also need to deal with the numerous problems and illnesses that come along with it. This refers to the risk of developing chronic cardiac conditions, low blood pressure, and, in some circumstances, problems with blood sugar. However, FitSpresso even with its bright and bold claims, can help you efficiently manage your weight and completely avoid these extra uncomfortable problems. FitSpresso is a supplement that comes in the form of a pill, which makes it tasty, simple to swallow, and handy. According to the manufacturer, these diet tablets are GMO-free and toxic-free, making them edible. This is why we have things such as weight loss supplements. Thanks to modern advancements, we can just take a dietary supplement pill to bring about significant weight loss in a completely healthy and natural manner. Not only this, but dietary supplements can also support healthy blood sugar levels and help with insulin re

Jodi Mardesich works at the Ann Wigmore Institute, a living foods school in Puerto Rico. She was previously a staff writer for Fortune and the San-Jose Mercury News. Seven months ago, I wasn't even a vegetarian. I thought I'd skip most classes, but once I got here, I became morbidly fascinated with colon health, digestion, and the benefits of wheat grass, and I didn't miss a single class. At first I felt like utter crap-I had headaches daily, and I felt bitchy and exhausted. Detoxing, everyone at the institute called it. (They blame every unpleasant symptom on detoxing.) But about a week into my stay, I started to feel different. Energized. Mentally sharper. Happier. More serene. Lighter. (I lost 10 pounds in the first week and didn't really need to lose weight.) I slept less. I started waking at dawn and going to bed earlier than I would have left the house for a night of partying back home in New York. My eyes even started changing color. Not just the whites, which got whiter, but my irises changed, too-from very dark to a richer, reddish brown.

thank you for the article.

Wearing any magnetic bracelet or Bracelets for Pain might ease the pain caused due to arthritis of hips and knees, as the UK researchers proved. Anecdotal benefits already has been reported by the wearers yet studies are there which compare such bracelets with dumb version have produced a mixed result. The present study by the Medical Journal, British found the significant reduction of pain among more than 65 wearers. Again the Peninsular School Medical team said that the effect can be real and again depend on the individual's faith. Also, a magnet with high strength (about 170mTesla and above) is required to have an effect on the pain. Whatever is the mechanism, the benefits of magnetic bracelets seemed clinically useful. Women's are found to be wearing sleek stylish or broad bracelets of either silver plated, pure copper, bronze or gold plated which actually look good and many of you must have wondered what are these and if they are any sort of style statement or trend and many must have known what they actually are and wanted to know if they work or not. These are the magnetic therapy bracelets for women or Bracelets for Pain and you have guessed right so far, we are going to discuss, in this article. There is a variety of Bracelets for Pain. Simple magnetic copper bracelets, Turquoise leaf copper magnetic bracelets, copper double hearted magnetic bracelets, bracelets of copper with black onyx, copper leaf tiger eye magnetic bracelets, Two worlds copper bracelets, heavy magnetic bracelets with a cuff mirror touch, cuff solid shiny vines and flowery bracelet, crossroads magnetic bracelets with price range of $13-$49 are pretty popular, matching varied tastes of women with sleek, bold, beautiful designs and come with warranty and discounts too. It is advisable from some sources for pregnant women to not wear these Bracelets for Pain. People into sports can use these, these magnetic therapy bracelets for peop

Acne is a common skin diseases that affects people of all ages and causes pimples. Teenagers mostly suffer from acne because changes in hormone levels in their body. This post talks about the home remedies for acne treatment. Would you like to ...

Acne is a common skin diseases that affects people of all ages and causes pimples. Teenagers mostly suffer from acne because changes in hormone levels in their body. This post talks about the home remedies for acne treatment. Would you like to ...

"Your fitness and health change, my 5 tips to getting you started."

"Your fitness and health change, my 5 tips to getting you started."

Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration.\nYeom CH, Jung GC, Song KJ.\nJ Korean Med Sci. 2007 Feb;22(1):7-11.\nPMID: 17297243

Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D. Vieth R, Ladak Y, Walfish PG. J Clin Endocrinol Metab. 2003 Jan;88(1):185-91. PMID: 12519850 This study shows that all age groups exhibit a high prevalence of 25(OH)D insufficiency and secondary hyperparathyroidism. Older adults are just as efficient in maintaining 25(OH)D, but they need more vitamin D to produce the higher 25(OH)D concentrations required to overcome the hyperparathyroidism associated with their diminishing renal function

High-density lipoprotein cholesterol changes after continuous egg consumption in healthy adults. Mayurasakorn K, Srisura W, Sitphahul P, Hongto PO. J Med Assoc Thai. 2008 Mar;91(3):400-7. PMID: 18575296 CONCLUSION: In the majority of healthy adults, an addition of one egg per day to a normal fat diet could raise HDL-c levels and decreased the ratio of TC toHDL-c. Therefore, egg consumption might benefit blood cholesterol.

Macroscopical and histopathological changes in regressing primary and recurrent equine sarcoids during active specific bio-immunotherapy. Hallamaa RE, Saario E, Tallberg T. In Vivo. 2005 Jul-Aug;19(4):761-7. PMID: 15999546

Fish oil and tocopherol-induced changes in natural killer cell-mediated cytotoxicity and PGE2 synthesis in young and old mice. Meydani SN, Yogeeswaran G, Liu S, Baskar S, Meydani M. J Nutr. 1988 Oct;118(10):1245-52. PMID: 3183771