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The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls. Parish S, Peto R, Palmer A, Clarke R, Lewington S, Offer A, Whitlock G, Clark S, Youngman L, Sleight P, Collins R; International Studies of Infarct Survival Collaborators. Eur Heart J. 2009 Sep;30(17):2137-46. Epub 2009 Jun 11. PMID: 19520708 doi:10.1093/eurheartj/ehp221 Conclusion: Apolipoprotein ratios are more informative about risk than lipid fractions are. This suggests that, among lipoprotein particles of a particular type (LDL or HDL), some smaller and larger subtypes differ in their effects on risk. Direct measurements of even more specific subtypes of lipoprotein particles may be even more informative about risk.

Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study. Kim J, Lim SY, Shin A, Sung MK, Ro J, Kang HS, Lee KS, Kim SW, Lee ES. BMC Cancer. 2009 Jun 30;9:216. PMID: 19566923 doi: 10.1186/1471-2407-9-216 Conclusion These results suggest that high consumption of fatty fish is associated with a reduced risk for breast cancer, and that the intake of omega-3 fatty acids from fish is inversely associated with postmenopausal breast cancer risk

Hearing aids accessories, such as protective cases, are a must since it can be so costly to repair these precision instruments.Of course, you definitely need to buy a quality accessory to go with your device- a decent case can mean the difference between a broken hearing aid and a "whew" moment.

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Swine flu is disease caused by H1N1 Virus. Swine flu spread almost all states in India and report from India's Health ministry suggest death of over 1000 people and approximately 20000 cases reported this year. Swine flu is contagious and s ...

Swine flu is disease caused by H1N1 Virus. Swine flu spread almost all states in India and report from India's Health ministry suggest death of over 1000 people and approximately 20000 cases reported this year. Swine flu is contagious and s ...

Written by, Samuel K. Burlum, Investigative Reporter and author of The Green Lane, a syndicated column Published on 6/01/16, a SamBurlum.com Exclusive Who would have thought we would be paying upwards of two and three dollars in some cases for a bottle of water when thirty years ago a person would just put a glass under their faucet and drink what came out of the pipe. It seems our society took clean fresh water for drinking for granted, and now because so many of local fresh water sources have been polluted, many of us have resorted to purchasing water from the supermarket.

Written by, Samuel K. Burlum, Investigative Reporter and author of The Green Lane, a syndicated column Published on 6/01/16, a SamBurlum.com Exclusive Who would have thought we would be paying upwards of two and three dollars in some cases for a bottle of water when thirty years ago a person would just put a glass under their faucet and drink what came out of the pipe. It seems our society took clean fresh water for drinking for granted, and now because so many of local fresh water sources have been polluted, many of us have resorted to purchasing water from the supermarket.

A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer. Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL. J Natl Cancer Inst. 2007 Jul 18;99(14):1120-9. Epub 2007 Jul 10. PMID: 17623801

Fowke JH. Head and neck cancer: a case for inhibition by isothiocyanates and indoles from cruciferous vegetables. Eur J Cancer Prev. 2007 Aug;16(4):348-56. PMID: 17554208 [PubMed - in process]

Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: a longitudinal, nested case-control study in the Nordic countries. Tuohimaa P, Tenkanen L, Ahonen M, Lumme S, Jellum E, Hallmans G, Stattin P, Harvei S, Hakulinen T, Luostarinen T, Dillner J, Lehtinen M, Hakama M. Int J Cancer. 2004 Jan 1;108(1):104-8. PMID: 14618623 DOI: 10.1002/ijc.11375

Vitamin D and diabetes: improvement of glycemic control with vitamin D3 repletion. Schwalfenberg G. Can Fam Physician. 2008 Jun;54(6):864-6. PMID: 18556494 Conclusion These cases support information that is already known about VTD and its effect on the islet cell. As discussed above, this might be true only for vitamin D3 and not vitamin D2, although vitamin D2 has been shown to improve bone health. Vitamin D insufficiency or deficiency is common, and repletion might improve glycemic control early in type 2 diabetes. Diabetes is one of the fastest growing chronic diseases worldwide. Vitamin D3 is inexpensive and readily available. Well-designed clinical studies are required to ascertain if improving 25(OH)D levels from an insufficiency or deficiency to sufficiency improves glycemic control in diabetes. These studies need to be properly designed: a randomized controlled trial with VTD deficiency or insufficiency identified in diabetic patients of various ethnic

Why would vitamin D be prescribed when vitamin D3 is available over-the-counter? Let's review the known differences between vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol): --D3 is the human form; D2 is the non-human form found in plants. --Dose for dose, D3 is more effective at raising blood levels of 25-hydroxy vitamin D than D2. It requires roughly twice to 250% of the dose of D2 to match that of D3 (Trang H et al 1998). --D2 blood levels don't yield long-term sustained levels of 25-hydroxy vitamin D as does D3. When examined as a 28-day area under the curve (AUC--a superior measure of biologic exposure), D3 yields better than a 300% increased potency compared to D2. This means that it requires around 50,000 units D2 to match the effects of 15,000 units D3 (Armas LA et al 2004). --D2 has lower binding affinity for vitamin D-binding protein, compared to D3 --Mitochondrial vitamin D 25-hydroxylase converts D3 to the 25-hydroxylated form five times more rapidly than D2. --As we age, the ability to metabolize D2 is dramatically reduced, while D3 is not subject to this phenomenon

Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study. Stene LC, Joner G; Norwegian Childhood Diabetes Study Group. Am J Clin Nutr. 2003 Dec;78(6):1128-34. PMID: 14668274 Conclusion: Cod liver oil may reduce the risk of type 1 diabetes, perhaps through the antiinflammatory effects of long-chain n-3 fatty acids.

A prospective nested case-control study of vitamin D status and pancreatic cancer risk in male smokers. Stolzenberg-Solomon RZ, Vieth R, Azad A, Pietinen P, Taylor PR, Virtamo J, Albanes D. Cancer Res. 2006 Oct 15;66(20):10213-9. PMID: 17047087 doi: 10.1158/0008-5472.CAN-06-1876 Contrary to expectations, subjects with higher prediagnostic vitamin D status had an increased pancreatic cancer risk compared with those with lower status. Our findings need to be replicated in other populations and caution is warranted in their interpretation and implication. Our results are intriguing and may provide clues that further the understanding of the etiology of this highly fatal cancer.

Determining the Effects of Lipophilic Drugs on Membrane Structure by Solid-State NMR Spectroscopy: The Case of the Antioxidant Curcumin. Barry J, Fritz M, Brender JR, Smith PE, Lee DK, Ramamoorthy A. J Am Chem Soc. 2009 Mar 3. [Epub ahead of print]\nPMID: 19256547 DOI: 10.1021/ja809217u

Soy consumption reduces risk of ischemic stroke: a case-control study in southern china. Liang W, Lee AH, Binns CW, Huang R, Hu D, Shao H. Neuroepidemiology. 2009;33(2):111-6. Epub 2009 May 30. PMID: 19494552 DOI: 10.1159/000222093 Conclusion: The results provided evidence of inverse association between habitual soy food consumption and the risk of ischemic stroke for Chinese adults.

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