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This was the WHI review of data as it pertains to dementia and cognitive decline in women.  The take home here is that the data provides little evidence for premarin with or without medroxyprogesterone acetate in > 65 for prevention of dementia.  However, this is in women > 65 and studies show that younger women do indeed receive benefit, especially in those with early ovary removal.  Another point here, MPA (medroxyprogesterone acetate) increases cognitive decline.  Just don't take MPA, it is a bad drug all the way around!

Estrogen with progestin worsens cognitive decline in women >65.  Little can be taken from this study other than, medroxyprogesterone acetate is a bad drug and should not be given to women for any purpose, especially in those >65.  One wonders if bioidentical, physiologic hormone replacement would have the same effect?  I doubt it.  The likely negative impact of hormones on the brain in women >65 is due to the negative effects of MPA, the change in inflammatory cytokines, and the change in receptors.

Study finds little link to Testosterone replacement therapy to elevation in PSA in "healthy" men.  All the members of this study had negative prostate biopsies prior to therapy.

study finds little benefit from third generation aromatase inhibitor in reducing PSA.

Good article.  This article (case series) found that 40% of the men included had no increase in PSA with Testosterone.  One point on the Testosterone dosage is that they used androgen, which is an overdose of Testosterone.  That gives 60% that the PSA did increase.  These men had higher PSA to begin with which leads to the suggestion that the prostate cells were abnormal.  Those men that had a prostatectomy were more likely to have little if any increase in PSA.  This study did use a the 5 alpha reductase inhibitor dutasteride.

A little research can ensure informed selections when deciding to purchase infusion pumps. The more you know about these medical devices, the easier it becomes to choose the exact model and type you require.

data on androgen therapy in women is sparse at best.  The conclusion here is suspect: "evidence supports the short-term efficacy and safety of high physiological doses of T" for women with with hypoactive sexual desire, yet the same authors recommend against long-term therapy.  How do those 2 go together???  They don't.  Support with physiologic Testosterone when appropriate testing reveals low T and symptoms support the same.  This is a practice guideline that lacks evidence to strongly back it up because so little evidence exists.  Practice guidelines are for lazy physicians.

Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f

Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f

Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f

Study finds that Testosterone therapy reduces LUTS in men with low T.  The definition of low T is a little wide in this study.  Another study that contradicts the belief that Testosterone contributes to LUTS through the prostate.

2 grams daily of Spirulina shown to improve academic performance in children.  This study of children in Senegal found improvement in as little as 60 days.

too little/ too much estrogen can negatively effect thyroid function; hormone balance one of the 5 points to health

A recommendation that I agree with: Very little data available for Testosterone in women requires significant restraint and recommendation to limit use of Testosterone in women.

New study finds "modest" association between Testosterone, DHEA, and FSH with libido, masturbation, and climax in women.  The author describes them as "subtle".  The association was not statistically significant.  The study found a great association with relationships than with Testosterone. This study points out the complexity that is libido in women.  It also casts doubt on the massive Testosterone push in women with little documented data.

small study finds limited improvement in cognition in men with low T and mild Cognitive impairment.  Little application from this study.

low SHBG found to be more associated with metabolic syndrome in older men than low Testosterone.  The study consisted of 2502 men older than 70.  The authors proposed this occurs through the relationship between SHBG and insulin sensitivity.  I think that is a little too simplistic.

MMAS study finds an age associated decline in Total Testosterone and free Testosterone levels. This study focus on the % decline based on other variables i.e. age, BMI...IN contrast, a 3.5% rise in DHT levels were observed. There is debate about the correlation of serum DHT and intra-tissue DHT. In fact, studies suggest there is little correlation.

NIH panel review finds little empirical evidence to support the use of opioids in chronic pain.

Testosterone therapy in men with low T will improve lean body mass, some reduction in abdominal obesity, yet little effect in visceral obesity.