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finchloe121

5 Things You Need To Understand If You are Having Chronic Pain! - 0 views

www.pharmahealthonline.com/...if-you-are-having-chronic-pain

Health Pharmacy Medicicne

shared by finchloe121 on 24 Sep 22 - No Cached
  • finchloe121 on 24 Sep 22
     
    Chronic pain is a type of pain that usually lasts for weeks to months. This pain can come and go, and it can be anywhere in the body. Chronic pain can lead to anxiety, depression, and insomnia. Chronic pain is quite different from acute pain and there are some differences between the two types. People usually experience severe pain, when it is injured by a broken bone or a cut on the skin. This pain does not last long. Pain is not something that can be ignored. If it grows, it should be fixed. As fear and pain persist, one begins to think negatively. Long-term negative thoughts begin to form in his mind, a process called fear conditioning. This factor causes an increase in blood pressure and anxiety disorders. Chronic pain is difficult to treat, and results in increased pain, fear, and negative thoughts. Extreme levels of fear lead to more pain, and the cycle of pain threats can be difficult to break. One of the best pills used to treat body pain symptoms is Hydrocodone 325mg, which you can easily buy from any trusted online pharmacy, such as Pharma Health Online.
Nathan Goodyear

National Institutes of Health Pathways to Prevention Workshop: The Role of Opioids in t... - 0 views

annals.org/article.aspx

NIH opioids chronic pain pain health

shared by Nathan Goodyear on 16 Jan 15 - No Cached
  • Nathan Goodyear on 16 Jan 15
     
    NIH panel review finds little empirical evidence to support the use of opioids in chronic pain.
Nathan Goodyear

The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic... - 0 views

www.ncbi.nlm.nih.gov/...PMC3962576

microglia LDN low dose naltrexone pain inflammation

shared by Nathan Goodyear on 05 Jul 17 - No Cached
  • orally active competitive opioid receptor antagonist
  • 4.5 mg, though the dosage can vary a few milligrams below or above that common value
  • At the low dosage level, naltrexone exhibits paradoxical properties, including analgesia and anti-inflammatory actions
  • ...10 more annotations...
  • LDN may be an effective treatment for FM
  • In addition to the antagonist effect on mu-opioid and other opioid receptors, naltrexone simultaneously has an antagonist effect on non-opioid receptors (Toll-like receptor 4 or TLR4) that are found on macrophages such as microglia
  • It is via the non-opioid antagonist path that LDN is thought to exert its anti-inflammatory effects
  • Once activated, microglia produce inflammatory and excitatory factors that can cause sickness behaviors such as pain sensitivity, fatigue, cognitive disruption, sleep disorders, mood disorders, and general malaise
  • The neuroprotective action appears to result when microglia activation in the brain and spinal cord is inhibited
  • By suppressing microglia activation, naloxone reduces the production of reactive oxygen species and other potentially neuroexcitatory and neurotoxic chemicals
  • suppressed TNF-alpha, IL-6, MCP-1, and other inflammatory agents in peripheral macrophages
  • individuals with greater ESR at baseline experienced a greater drop in pain when taking LDN
  • LDN has been reported to reduce not only self-reported pain in that condition but also objective markers of inflammation and disease severity
  • Naltrexone has also shown some promise in improving disease severity in multiple sclerosis
  • Nathan Goodyear on 05 Jul 17
     
    LDN maybe useful in treating chronic pain via anti-inflammatory effects on microglia.
Nathan Goodyear

Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic w... - 0 views

www.ncbi.nlm.nih.gov/...PMC1257426

stress HPA adrenal adrenals cortisol saliva salivary pain

shared by Nathan Goodyear on 01 May 12 - No Cached
  • Nathan Goodyear on 01 May 12
     
    Those with chronic pain shown to have HPA dysfunction.  Elevated cortisol was found via saliva evaluation.  This with pain had the higher cortisol levels.
Nathan Goodyear

Ketamine in Chronic Pain Management: An Evidence-Based Review - 0 views

www.anesthesia-analgesia.org/...1730.abstract

transdermal ketamine pain fibromyalgia

shared by Nathan Goodyear on 20 Oct 11 - No Cached
  • Nathan Goodyear on 20 Oct 11
     
    transdermal ketamine for chronic pain management
dblendstore

Overview of Pain Management Treatment - DBlend Store - 0 views

dblendstore.com/w-of-pain-management-treatment

cancer hormones Testosterone disease men health drugs

shared by dblendstore on 11 Aug 21 - No Cached
  • dblendstore on 11 Aug 21
     
    Chronic pain treatments are as varied as its causes. There are numerous approaches available, ranging from over-the-counter and prescription drugs to mind/body techniques and acupuncture. However, when it comes to treating chronic pain, no single technique can guarantee complete pain relief. A combination of treatment options may provide relief.
Nathan Goodyear

Quercetin in men with category III chronic prostatitis: a preliminary prospective, doub... - 0 views

www.ncbi.nlm.nih.gov/...10604689

quercetin bioflavonoids prostatitis prostate disease natural medicine alternative medicine

shared by Nathan Goodyear on 25 Sep 15 - No Cached
  • Nathan Goodyear on 25 Sep 15
     
    quercetin useful in reducing pain associated with chronic prostatitis.
Nathan Goodyear

Oxytrex Minimizes Physical Dependence While Providing Effective Analgesia: A Randomized... - 0 views

www.jpain.org/...abstract

naltrexone pain control opiates

shared by Nathan Goodyear on 19 May 11 - No Cached
  • Active treatment groups attained comparable analgesia despite significantly lower drug use
  • preclinical data also show a suppression of opioid tolerance and dependence
  • Previous clinical data have shown ultralow-dose naltrexone enhances and prolongs oxycodone analgesia,
  • ...1 more annotation...
  • A cellular mechanism of action has been demonstrated to be the prevention of aberrant G protein signaling by mu opioid receptors caused by chronic opioid administration
  • Nathan Goodyear on 19 May 11
     
    low dose naltrexone improves pain control and reduced opioid addiction
spineneuro

Top Minimally Invasive Spine Surgeon Mumbai India Raising Care in India to A New Level - 0 views

www.linkedin.com/...umbai-india-new-hospital-india

Top minimally invasive spine surgeon Mumbai India cost of robotic spine surgery in India

shared by spineneuro on 01 Sep 21 - No Cached
  • spineneuro on 01 Sep 21
     
    Top minimally invasive spine surgeon Mumbai India is willing to serve you with the best medical assistance to help you to ease your chronic back pain. The cost of robotic spine surgery in India is turning very affordable. Please call: +91-9325887033 Email id: enquiry@spineandneurosurgeryhospitalindia.com
Nathan Goodyear

HPA Axis Reactivity and Lymphocyte Glucocorticoid Sensitivity in Fibromyalgia Syndrome ... - 0 views

www.psychosomaticmedicine.org/...65.abstract

fibromyalgia saliva salivary cortisol urinary metabolites stress HPA

shared by Nathan Goodyear on 24 Apr 12 - No Cached
  • Nathan Goodyear on 24 Apr 12
     
    Individuals with Fibromyalgia shown to have lowered salivary cortisol levels.  This study suggested that this could be due to reduced adrenal reactivity to ACTH.  Another thought, is there increased metabolism of cortisol in these clients.  This would be found in the urinary metabolites.
Nathan Goodyear

Horse chestnut seed extract for chronic venous insufficiency - 0 views

www2.cochrane.org/...ab003230.html

extract horse chestnut varicose veins seed

shared by Nathan Goodyear on 24 Feb 11 - No Cached
  • Overall, the trials suggested an improvement in the symptoms of leg pain, oedema and pruritus
  • The evidence presented suggests that HCSE is an efficacious and safe short-term treatment for CVI
  • Nathan Goodyear on 24 Feb 11
     
    horse chestnut effective in reducing symptoms of varicose veins
wheelchairindia9

Karma KM 2500 Wheelchair - 0 views

www.wheelchairmanufacturers.in/...KM-2500-Small-Wheel-Wheelchair

Lightweight Karma KM 2500 Small Wheelchair Overall Collapsed Width KM 2500 Wheelchair Karma KM 2500 Wheelchair Karma KM 2500 convenience and comfort to the user benefit of increased mobility

shared by wheelchairindia9 on 19 Oct 15 - No Cached
  • wheelchairindia9 on 19 Oct 15
     
    Karma KM 2500 Small Wheel Wheelchair: Karma KM 2500 Small Wheel Wheelchair Specifications: Width 18" Front/Rear Wheels 6" to 14" Seat Width 47cm Seat Depth 40cm Overall Width 66cm Overall Collapsed Width 36cm Armrest Height 21cm Overall Length 90cm Seat Height 47cm Backrest Height 38cm Overall Height 86cm Weight 9.2 k.g. Karma KM 2500 Small Wheel Wheelchair Seat and Back: AEGIS Microbe Shield Approved by the FDA, EPA, EU, etc., bonded anti-microbial barrier upholstery protects from odor, staining and deterioration from bacteria, fungus and other microorganisms. It is a shield for your health. Karma KM 2500 Small Wheel Wheelchair Extended Armrest: By simulating the natural position of arms, the extended armrest design is ergonomic and creates bigger seating space. An Ultra lightweight wheelchair (9.2 kg) with a compact design for either attendant assisted or self propelling users. The use of aircraft-grade aluminium alloy and double cross brace provide this model with outstanding strength and durability. Karma Healthcare KM-2500 Premium Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 9.2 kg making it easy for anyone to lift into a vehicle. Backrest folds-down for easy transportation. Maximum user weight: 100 K.g. Aluminium frame. Fixed armrest/fixed footrest. Foldable frame via double cross bars. Comfortable & durable upholstery. Swing-away foot plates. Puncture proof tyres. Attendant cable brake. 14" flat-free rear wheels. Detachable and washable cushion. One Year Warranty. It folds down to take up virtually no space in the boot of a car. This amazingly light and compact transit wheelchair is ideal for outings and travelling. It comes with detachable and washable cushion. The wheel chair has attendant cable brake. It is made from aircraft-grade aluminium alloy fra
Nathan Goodyear

The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture - 0 views

www.ncbi.nlm.nih.gov/...PMC2921747

flouroquinolones ciprofloxacin levoquin tendinitis tendinopathy Tendon rupture

shared by Nathan Goodyear on 02 Aug 17 - No Cached
  • Achilles tendinitis or rupture is among the most serious side effects associated with FQ use
  • The large body of data provided by clinical reports, histopathological examination, and experimental studies provides cogent evidence supporting a direct link between FQ use and tendonitis/tendon rupture
  • Risk factors associated with FQ-induced tendon disorders include age greater than 60 years, corticosteroid therapy, renal failure, diabetes mellitus, and a history of musculoskeletal disorders
  • ...17 more annotations...
  • The average age of FQ-induced tendinopathy is 64 years, with a male-to-female ratio of 2:1, and a 27-percent incidence of bilateral involvement
  • Although more than 95 percent of cases of tendinitis/rupture secondary to FQ involve the Achilles tendon, other reported sites of tendon involvement include the quadriceps, peroneus brevis, and rotator cuff
  • FQs demonstrate a 3.8-fold greater risk for development of Achilles tendinitis/rupture
  • a large population-based case control analysis, patients treated with FQs exhibited a substantially increased risk of developing tendon disorders overall (1.7-fold), tendon rupture (1.3-fold), and ATR (4.1-fold)
  • patients taking FQs with concurrent exposure to corticosteroids were found to experience a compounding effect on the risk of tendon rupture, specifically a 46-fold greater predisposition
  • Some authors have recommended that patients with a history of Achilles tendinitis and advanced age should not be prescribed FQ antibiotics
  • Approximately 50 percent of patients will recover within 30 days, with 25 percent of patients having symptoms persistent for longer than two months
  • The mean latency period between the start of FQ treatment and occurrence of tendinopathy has been reported to be a few hours to months, with a median onset of 6 days
  • The exact pathophysiology of FQ-induced tendinopathy remains elusive
  • it is possible that FQs have a direct cytotoxic effect on enzymes found in mammalian musculoskeletal tissue
  • It has been theorized that FQs disproportionately affect human tendons that have a limited capacity for repair, such as in older patients or structural compromise (i.e., pre-existing tendinopathy or trauma)
  • histopathological findings are similar to those observed in overuse conditions in athletes
  • Treatment with a FQ should be discontinued and physical therapy initiated
  • treatment should include rest and decreasing the physical load on the tendon.
  • Approximately 85 percent of patients present in less than one month
  • Because rupture can occur even late in the course of treatment or after discontinuation of FQ use, patients receiving a FQ should be counseled to seek medical attention immediately if symptoms, such as redness, pain, swelling, and stiffness, develop
  • FQs should be used cautiously in patients with risk factors associated with tendinitis, such as advanced age, history of tendon rupture, corticosteroid use, and/or acute or chronic renal dysfunction
  • Nathan Goodyear on 02 Aug 17
     
    Great review of the link between flouroquinolones and Tendinitis and Tendon rupture.  Yes, there is a direct link.
Nathan Goodyear

Pharmaceuticals | Free Full-Text | Chronic Cannabigerol as an Effective Therapeutic for... - 0 views

www.mdpi.com/...1442

cisplatin cannabigerol neuropathy CBG phytocannabinoids

shared by Nathan Goodyear on 20 Apr 24 - No Cached
  • Nathan Goodyear on 20 Apr 24
     
    10 mg/kg in males and 15 mg/kg in females without side effects
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