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Nathan Goodyear

Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment | The BMJ - 0 views

www.bmj.com/bmj.i6865

thyroid disease thyroid functional hypothyroidism hypothroidism fertility infertility

shared by Nathan Goodyear on 13 Mar 17 - No Cached
  • Nathan Goodyear on 13 Mar 17
     
    Thyroid therapy in women with subclinical hypothyroidism found to have improved pregnancy rates (lower pregnancy loss).
Nathan Goodyear

Nutrition Journal | Full text | Consumption habits of pregnant women and implications for developmental biology: a survey of predominantly Hispanic women in California - 0 views

www.nutritionj.com/...91

nutrition pregnancy

shared by Nathan Goodyear on 30 Sep 13 - No Cached
  • Nathan Goodyear on 30 Sep 13
     
    Prenatal counseling must include nutritional counseling prior to pregnancy.  The key window to act is prior to pregnancy.  That is a reactive posture.  
Nathan Goodyear

Estriol and Progesterone: A New Role for Sex Hormones - 0 views

www.ncbi.nlm.nih.gov/...PMC3614637

Estriol Progesterone autoimmune disease inflammation hormones

shared by Nathan Goodyear on 09 May 16 - No Cached
  • Pregnancy-associated Th2 shift has been proposed as a mechanism underlying the improvement of Th1-mediated autoimmune diseases (as rheumatoid arthritis, multiple sclerosis (MS), autoimmune thyoriditis, uveitis, and psoriatic arthritis
  • Th2-mediated autoimmune diseases (as systemic lupus erythematosus)
  • During pregnancy PRG serum level increases by a factor of 4, while estrogen estriol (E3) serum concentration increases by a factor of 20
  • ...1 more annotation...
  • In pregnant women at or near term there is a daily production of about 300 μmol (80 mg) of E3 and 1 mmol (300 mg) of PRG
  • Nathan Goodyear on 09 May 16
     
    Estriol and Progesterone associated, as found with pregnancy, associated with decrease in Th1 autoimmune disease.
Nathan Goodyear

Targeting gut microbiota in obesity: effects of prebiotics and probiotics : Article : Nature Reviews Endocrinology - 0 views

www.nature.com/...nrendo.2011.126.html

LPS lipopolysaccharides gut microbiota dysbiosis inflammation obesity metabolic endotoxemia health probiotics

shared by Nathan Goodyear on 18 Jan 12 - No Cached
  • gut microbes have a role in the host's metabolic homeostasis
  • lipopolysaccharide (LPS)
  • Associations between circulating LPS level, consumption of a high-fat diet and the presence of obesity and type 2 diabetes mellitus have been confirmed in humans
  • ...8 more annotations...
  • associations have been proposed between high-fat diet, metabolic endotoxemia and levels of inflammatory markers (TLRs and SOCS3) in mononuclear cells
  • A link between energy intake (high-fat diet) and metabolic endotoxemia has also been described
  • high-fat diet induces metabolic endotoxemia in healthy individuals.
  • metabolic endotoxemia is associated with systemic and adipose tissue inflammation in pregnant women with obesity
  • A growing amount of evidence indicates that changes in the integrity of the intestinal barrier occur both in the proximal and the distal part of the gut, which can contribute to the entrance of LPS into the systemic circulation
  • intestinal endocannabinoid system
  • The low-grade systemic inflammation that characterizes the obese phenotype is controlled by peptides that are produced in the gut. These peptides are influenced by the presence or absence of the gut microbiota
  • these findings suggest that the gut microbiota modulates the biological systems that regulate the availability of nutrients, energy storage, fat mass development and inflammation in the host, which are all components of the obese phenotype
  • Nathan Goodyear on 18 Jan 12
     
    good look of how the the gut health, or lack there of, can influence energy homeostasis and contribute to obesity.  This article points to the presence of LPS playing a role in metabolic endotoxemia.  It does discuss the importance of the microbiota and their possible role in the low-grade systemic inflammation condition that is obesity.
Nathan Goodyear

Lower Rate of Preeclampsia After Antioxidant Supplementation in Pregnant Women with Low Antioxidant Status, Hypertension in Pregnancy, Informa Healthcare - 0 views

informahealthcare.com/...10641950600913016

antioxidant antioxidants pregnancy detoxification NAC N-acetylcysteine pre-eclampsia preeclampsia hypertension

shared by Nathan Goodyear on 02 Mar 12 - No Cached
  • Nathan Goodyear on 02 Mar 12
     
    antioxidant support in early pregnancy, including NAC, shown to reduce the incidence in pre-eclampsia
Nathan Goodyear

Glucose Targets in Pregnant Women With Diabetes: A Systematic Review and Meta-Analysis - 0 views

jcem.endojournals.org/...4319.abstract

glucose pregnancy diabetes

shared by Nathan Goodyear on 18 Nov 13 - No Cached
  • Nathan Goodyear on 18 Nov 13
     
    Target range for glucose in pregnancy should be < 90.
Nathan Goodyear

Environmental Health Perspectives: Environmental Chemicals in Pregnant Women in the US: NHANES 2003-2004 - 0 views

ehp03.niehs.nih.gov/...fetchArticle.action

health environmental pregnancy toxic toxins

shared by Nathan Goodyear on 17 Jan 11 - No Cached
  • Nathan Goodyear on 17 Jan 11
     
    100% of expecting mothers found to be toxic
Nathan Goodyear

Protein Requirements of Healthy Pregnant Women during Early and Late Gestation Are Higher than Current Recommendations - 0 views

jn.nutrition.org/...73.abstract

pregnancy protein diet nutrition

shared by Nathan Goodyear on 23 Mar 15 - No Cached
  • Nathan Goodyear on 23 Mar 15
     
    Current recommendations for dietary protein intake during pregnancy is to low.  New study points to 1.22 g/kg and 1.52 g/kg requirements for first and third trimester.
Nathan Goodyear

The normal vaginal flora, H2O2-producing lactobacilli, and bacterial vaginosis in pregnant women. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8324131

vaginal flora H2O2 flora lactobacillus BV vaginosis bacterial vaginosis microbiome female

shared by Nathan Goodyear on 29 Feb 16 - No Cached
  • Nathan Goodyear on 29 Feb 16
     
    vaginal flora.  Lactobacillus produce H202.
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