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Nathan Goodyear

Increased prevalence of onychomycosis among psoriatic patients in Israel. - PubMed - NCBI - 0 views

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    higher prevalence of toe nail fungus in those with psoriasis vs controls.
Nathan Goodyear

The 20-Year Public Health Impact and Direct Cost of Testosterone Deficiency in U.S. Men... - 0 views

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    This study assumes a 13% low T prevalence.  Probably too low.  This will only grow.  Low T contributes to many disease states in men. This study showed a cost of 190-525$ billion in cost from these disease states over a 20 year time period.
Nathan Goodyear

ADDM Network 2012 - 0 views

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    Government review of trends of states reporting on Autism incidence/prevalence. The question, is why are not all of the state following this? Especially Louisiana and Mississippi.
Nathan Goodyear

Mild Traumatic Brain Injury in UK Military Personnel Returni... : The Journal of Head T... - 0 views

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    Prevalence of mild Traumatic Brain Injury was found to be 9.5% in returning US soldiers.  This was associated with PTSD and Etoh abuse.
Nathan Goodyear

A radical approach to stroke therapy - 0 views

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    vitamin C shown to benefit stroke patients.  Vitamin C, ascorbic acid, is extremely prevalent in the brain.  Functions to scavenge free radicals
Nathan Goodyear

JAMA Network | Archives of Neurology | Reduced Risk of Alzheimer Disease in Users of An... - 0 views

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    Use of Vitamin C and Vitamin E associated with a 78% reduced prevalence of Alzheimer's disease.
Nathan Goodyear

Products - Health E Stats - Overweight, Obesity, and Extreme Obesity Among Adults 2007-... - 0 views

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    scary statistics of the prevalence and the trends of obesity in the US.
Nathan Goodyear

Vitamin D Deficiency in Critically Ill Children - 0 views

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    vitamin D deficiency found highly prevalent in children with critical illness
Nathan Goodyear

The Association of Vitamin D Status With Pediatric Critical Illness - 0 views

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    Vitamin D deficiency found more prevalent in those children with critical illnesses; and with greater severity of illness.
Nathan Goodyear

Effects of a dietary intervention and weight change on vasom... : Menopause - 0 views

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    Hot flashes reduced with weight loss in those not taking HRT.  Reduced fat equals reduced inflammation equals reduced hot flashes/night sweats.  The more inflamed an individual, the more prevalent/significant the hot flashes.
Nathan Goodyear

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evide... - 0 views

  • Older men were more likely to have primary [relative risk ratio (RRR) = 3.04; P < 0.001] and compensated (RRR = 2.41; P < 0.001) hypogonadism. Body mass index of 30 kg/m2 or higher was associated with secondary hypogonadism (RRR = 8.74; P < 0.001)
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    The prevalence of low T varies significantly between lean versus overweight men.  This suggests a significant contribution of obesity and its biologic effects as a cause of low T.  The difference is 30%.
Nathan Goodyear

Nature Clinical Practice Endocrinology & Metabolism | Testosterone and ill-health in ag... - 0 views

  • Levels of total and bioavailable testosterone and SHBG were reported to be inversely correlated with the prevalence of the metabolic syndrome in men aged 40–80 years
  • as were total testosterone and SHBG in men aged 65–96 years
  • and in a cross-sectional analysis of a large cohort of non-diabetic men aged 70–89 years
  • ...18 more annotations...
  • In longitudinal studies, decreased levels of total testosterone and SHBG predicted an increased incidence of metabolic syndrome in nonobese men
  • Free testosterone level is not associated with the prevalence of metabolic syndrome in middle-aged and older men
  • Levels of free, bioavailable and total testosterone are lower in men with T2DM than in age-matched controls,34, 35 and decreased total testosterone level predicts incident T2DM in middle-aged men.
  • men with T2DM commonly have low total or free testosterone levels
  • Total, bioavailable and free testosterone levels are inversely correlated with fasting insulin level and insulin resistance in middle-aged men without T2DM
  • total testosterone is positively correlated with insulin sensitivity in men with normal or impaired glucose tolerance or T2DM
  • low SHBG level is more strongly associated with metabolic syndrome than low total testosterone in aging men
  • the recognized association between low SHBG level and insulin resistance
  • Low levels of SHBG are also associated with smaller, denser LDL-cholesterol molecules in nondiabetic men,58 and were found to predict increased cardiovascular disease mortality in one study of older men
  • Low levels of SHBG might reflect obesity, insulin resistance and overall poor health
  • Compared with those who have normal testosterone levels, men aged 40 years or more with total testosterone levels <9.8 nmol/l or elevated LH level have greater CIMT
  • In men aged 73–94 years, total testosterone was inversely correlated with CIMT
  • a prospective analysis of men aged 73–91 years, progression of CIMT was not related to total testosterone level, but it was inversely related to free testosterone level
  • A study of men aged 55 years or more found that those with total and bioavailable testosterone levels in the highest tertile had a lower risk of severe aortic atherosclerosis (detected by radiography as abdominal aortic calcification) than those with the lowest testosterone levels.
  • a large study of men aged 69–80 years, those with total or free testosterone in the lowest quartile had increased odds of lower-extremity peripheral arterial disease
  • the possibility of reverse causation has to be considered, as systemic illness can result in decreased testosterone levels
  • previous case–control studies and longitudinal studies have failed to identify low testosterone levels as strong predictors of clinically significant coronary disease
  • Reviews of trials on testosterone therapy in men with either low or low-to-normal testosterone levels have not shown consistent beneficial effects either on lipid profiles or on actual cardiovascular events.24, 54, 55 These trials, however, have not been designed or powered to detect treatment-related differences in cardiovascular outcome
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    Declining Testosterone or low Testosterone is clearly associated with poor health in men.   Very nice review of the association between low Testosterone and metabolic dysfunction.  Low T is associated with increased metabolic syndrome, Diabetes, weight gain, insulin resistance...
Nathan Goodyear

Efficacy of liposomal curcumin in a human pan... [Anticancer Res. 2013] - PubMed - NCBI - 0 views

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    liposomal curcumin at 20 mg/kg reduced pancreatic tumor growth by 42% in in vitro and xenograft studies.  The curcumin, the most prevalent polyphenol in tumeric, was given intraperitoneal in this study.
Nathan Goodyear

Exposure to DEHP and MEHP from hatching to adu... [Aquat Toxicol. 2013] - PubMed - NCBI - 0 views

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    endocrine disrupting pthalates disrupt marine animal hormones.  This effect was more prevalent in males than females.
Nathan Goodyear

Enteropathogens associated with a... [FEMS Immunol Med Microbiol. 2002] - PubMed - NCBI - 0 views

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    multiple parasite infection cause of many cases of diarrhea.  A common combination of Blastocystis hominis and Endolimax nana is prevalent.
Nathan Goodyear

Resistance training restores muscle sex steroid hormone steroidogenesis in older men - 0 views

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    I like this study.  So many men, and women for that matter, focus on cardio for health and weight loss.  In men, low Testosterone is associated with aging as is weight.  This inverse relationship leads to the sarcopenic (belly, manboobs, and thin arms/legs) obesity so prevalent in older men today.  This study found that older men do have lower levels of enzymes and androgens from muscle biopsies as compared to younger men.  A 12 week resistance training regimen of only knee flexion and extension (simple) resulted in increased 3-beta-hydroxysteroid dehydrogenase and 17-beta-hydroxysteroid dehydrogenase.  
Nathan Goodyear

New Prevalence Study Suggests Dramatically Rising Numbers of People with Alzheimer's Di... - 0 views

  • Scientists project that some 13.2 million older Americans will have Alzheimer's disease (AD) by 2050
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    neurodegenerative disease on the rise, unless we become very proactive
Nathan Goodyear

Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in t... - 0 views

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    Autism spectrum has increased to 1 in 91 in American Children
Nathan Goodyear

Cardiometabolic abnormalities in current National ... [Am J Cardiol. 2009] - PubMed result - 0 views

  • cardiometabolic syndrome and its individual components were noted in current NFL players, particularly linemen.
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    cardiometabolic disease more prevalent in NFL lineman
Nathan Goodyear

Age, Insulin Requirements, Waist Circumference, and Triglycerides P... - PubMed - NCBI - 0 views

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    Study looked at low T in men with type 1 Diabetes.  Only abstract available here.  Study finds appx 10% prevalence with age, waist circumference and insulin requirements as predictive of low T in men with type 1 Diabetes.
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