Group items tagged

cardiometabolic disease more prevalent in NFL lineman

study finds Pb and Hg associated with increased cardiometabolic risk factors.  Elevated liver enzymes found to be positively associated with serum Pb levels.  Metabolic Syndrome was found to be associated with higher Pb and Hg levels.

wine, red and white, with a mediterranean diet reduced cardiometabolic risk  in individuals with diabetes.  The volume of nightly intake of wine was 5 oz.

Study questions causal associations of testosterone and cardiometabolic risk.  In this analysis they used to SNPs, one on the SHBG gene rs12150660 and the other on the X chromosome rs59344505.

A study by scientists in a UK university has shown the scale of the prevalence of a condition that can lead to various cardiometabolic diseases. The study published in the Annals of Internal Medicine journal on Tuesday (January 4) has prompted calls for changes to healthcare policy after researchers revealed, for the first time, the scale of the impact of the condition associated with benign tumours that can lead to type 2 diabetes and high blood pressure. Up to 10 per cent of adults have a benign tumour, or lump, known as an 'adrenal incidentaloma' in their adrenal glands which can be associated with the overproduction of hormones including the stress steroid hormone cortisol that can lead to type 2 diabetes and high blood pressure. Previous small studies suggested that one in three adrenal incidentalomas produce excess cortisol, a condition called mild autonomous cortisol secretion (MACS). An international research team led by the University of Birmingham carried out the largest ever prospective study of over 1,305 patients with adrenal incidentalomas to assess their risk of high blood pressure and type 2 diabetes and their cortisol production by comparing patients with and without MACS.

Higher vitamin D levels associated with lower cardio biomarkers: insulin, insulin resistance, triglycerides, TC, LDL and TC:HDL.  Not found to be associated: glucose, apoliporotein A1 and B, CRP, fibrinogen, and homocysteine.

low Testosterone associated with increased CVD and death.

Obesity of pregnant mothers effect the future cardiovascular health of their future children. The time to work on the health of your future children, is before couples actually get pregnant.

Earlier puberty associated with increased risk of MetS and obesity.

This study looked at oral Testosterone plus fenofibrate (tricor).  That is not the purpose of this post.  This study found that oral Testosterone decanoate reduced hsCRP and improved insulin sensitivity.  One caveat--Testosterone should not be given orally due to increased risk of hepatocellular cancer.

Study finds heavy presence of xenoestrogens in obese Portuguese women, both pre menopause and post menopause.  This study only looked at obese women; it would be nice to have a control of thin women to contrast the plasma and adipose xenoestrogen levels.  The authors found the presence of xenoestrogens in plasma in pre menopause women to be a 10 year predictor of cardiovascular disease risk in these women.  The authors also found increased Xenoestrogen levels to be associated with metabolic dysfunction and inflammation.

low Testosterone increase cardiovascular risk factors

19% of University of Tennessee football players shown to have metabolic syndrome; 46% of the offensive lineman shown to have metabolic syndrome