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fnfdoc

Psoriasis: Causes, Symptoms, Types & Treatment - Health Blog - 0 views

fnfdoc.com/auses-symptoms-types-treatment

Psoriasis Psoriasis Causes Psoriasis Symptoms Psoriasis Types Psoriasis Treatment Common Causes Of Psoriasis Most Common Causes Of Psoriasis Genetics and Psoriasis Microbes And Psoriasis Key Signs And Symptoms Of Psoriasis Diagnose Psoriasis Most Popular

shared by fnfdoc on 11 Apr 20 - No Cached
  • fnfdoc on 11 Apr 20
     
    Psoriasis is a chronic skin condition that accelerates the rate at which your skin cells grow. An effective method to treat psoriasis is phototherapy or light therapy.
  • fnfdoc on 11 Apr 20
     
    Psoriasis is an auto-immune illness that affects almost three percent of the world's population. People who suffer from psoriasis experience a great deal of skin irritation and discomfort.
SEO Husain

Psoriasis information & treatment - Treat your Psoriasis with Homeopathy at Dr. Batra's - 0 views

www.drbatras.com/psoriasis

obesity hormone inflammation salivary saliva hormones disease cancer testing testosterone

shared by SEO Husain on 22 Aug 12 - No Cached
  • SEO Husain on 22 Aug 12
     
    Psoriasis is an auto-immune chronic condition that affects the growth cycle of skin cells. Treat your Psoriasis with Homeopathy at Dr. Batra's.
Nathan Goodyear

Hypogonadal men with psoriasis benefit from long-term testosterone replacement therapy ... - 0 views

www.ncbi.nlm.nih.gov/...26184426

low T low Testosterone Testosterone psoriasis CRP inflammation lipids obesity men

shared by Nathan Goodyear on 12 Aug 15 - No Cached
  • Nathan Goodyear on 12 Aug 15
     
    only abstract available here, but Testosterone therapy in men with low T found to reduce CRP, weight and lipids in men with psoriasis.
Nathan Goodyear

Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and... - 0 views

ard.bmj.com/...annrheumdis-2014-205675

inflammation cardiovascular RA rheumatoid arthritis psoriasis disease CVD

shared by Nathan Goodyear on 20 Nov 14 - No Cached
  • Nathan Goodyear on 20 Nov 14
     
    Abstract: Inflammatory diesease (psoriasis and RA in this study) associated with increased cardiovascular events.
Nathan Goodyear

Association of Psoriasis Severity with Serum Prolactin, Thyroid Hormones, and Cortisol... - 0 views

www.hindawi.com/...921819

psoriasis prolactin cortisol thyroid hormones T3 autoimmune disease autoimmune

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    study suggests that PrL, T3 and cortisol may impact psoriasis treatment in positive manner.
Nathan Goodyear

Evaluation of candidal colonization and specific humoral responses against Candida albi... - 0 views

onlinelibrary.wiley.com/...abstract

candida candida albicans candidiasis yeast psoriasis dermatology

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    higher colonization of candida albicans found in people with psoriasis vs controls.  Higher in oral cultures vs skin.
Nathan Goodyear

Incidence of Candida in psoriasis--a study on the fungal flora of psoriatic patients. -... - 0 views

www.ncbi.nlm.nih.gov/...11413927

candida candida albicans candidiasis psoriasis dermatology yeast

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    statistically higher candida detected in those with psoriasis vs controls.
Nathan Goodyear

Cure of Psoriasis and Arthritis when Addison's Disease Was Detected - 0 views

www.ncbi.nlm.nih.gov/...PMC2988843

cortisol psoriasis autoimmune disease autoimmune addison's disease

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    case study: addison's disease associated with psoriasis.  
Nathan Goodyear

The role of microorganisms in psoriasis. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...2285571

gut bacteria gut flora gut health gut microbiome gut microbiota psoriasis

shared by Nathan Goodyear on 19 Apr 17 - No Cached
  • Nathan Goodyear on 19 Apr 17
     
    gut bacteria implicated in psoriasis
Nathan Goodyear

Increased prevalence of onychomycosis among psoriatic patients in Israel. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18176747

candida yeast fungus psoriasis

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    higher prevalence of toe nail fungus in those with psoriasis vs controls.
Nathan Goodyear

Effects of a Skin Neuropeptide (Substance P) on Cutaneous Microflora - 0 views

journals.plos.org/...article

skin substance P bacillus cereus psoriasis

shared by Nathan Goodyear on 19 Apr 17 - No Cached
  • Nathan Goodyear on 19 Apr 17
     
    substance P from skin flora, i.e. bacillus cereus, implicated in skin disease like psoriasis, acne, rosacea...
Nathan Goodyear

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607638/pdf/jnma00404-0073.pdf - 0 views

www.ncbi.nlm.nih.gov/...jnma00404-0073.pdf

psoriasis gut bacteria gut flora gut microbiome gut microbiota

shared by Nathan Goodyear on 19 Apr 17 - No Cached
  • Nathan Goodyear on 19 Apr 17
     
    gut bacteria implicated in psoriasis.
Nathan Goodyear

Immune Modulation in Multiple Sclerosis Patients Treated with the Pregnancy Hormone Est... - 0 views

www.jimmunol.org/...6267.long

MS RA rheumatoid arthritis psoriasis multiple sclerosis Estriol autoimmune disease inflammation hormone hormones E3

shared by Nathan Goodyear on 19 Mar 14 - No Cached
  • A beneficial effect of pregnancy on clinical symptoms has been observed in MS and other Th1-mediated autoimmune diseases, including rheumatoid arthritis (RA), psoriasis, uveitis, and thyroiditis
  • In general, Th1 lymphocytes secrete proinflammatory cytokines (e.g., IL-2, IL-12, IFN-γ, and TNF-α) that promote cellular immunity, while Th2 lymphocytes produce anti-inflammatory cytokines (e.g., IL-4, IL-5, IL-6, and IL-10) that promote humoral immunity
  • Th2 cytokines are associated with the down-regulation of Th1 cytokines and may confer protection from Th1-mediated autoimmune diseases
  • ...1 more annotation...
  • During pregnancy, there is a shift from Th1 to Th2 that occurs both locally, at the fetal maternal interface, (23, 24, 25), and systemically
  • Nathan Goodyear on 19 Mar 14
     
    MS is in part a Th1 autoimmune disease.  Estriol therapy induces a shift to Th2 through increase in Th10.  Estriol also decreases TNF-alpha cytokine production.
Nathan Goodyear

Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoria... - 0 views

www.researchgate.net/...phigoidpemphigus_and_psoriasis

DHEA DHEAS dehydroepiandrostenedione hormones autoimmune disease autoimmune lupus psoriasis

shared by Nathan Goodyear on 03 Dec 15 - No Cached
  • Nathan Goodyear on 03 Dec 15
     
    low DHEA found in individuals with autoimmune disease.  The authors conclude that this may contribute to the cause of the disease(s)
Nathan Goodyear

Psoriatic Arthritis and the Complications of Systemic Inflammation (Dec 2014) Townsend ... - 0 views

www.townsendletter.com/...notskin1214_2.html

arthritis psoriasis psoriatic arthritis inflammation disease

shared by Nathan Goodyear on 09 Aug 16 - No Cached
  • Nathan Goodyear on 09 Aug 16
     
    review of natural treatment of psoriatic arthritis.
Nathan Goodyear

Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer ... - 0 views

www.ncbi.nlm.nih.gov/...PMC5718030

chloroquine hydroxychloroquine cancer repurposed drugs

shared by Nathan Goodyear on 03 May 21 - No Cached
  • HCQ, doses for long-term use range between 200 and 400 mg per day.
  • Short-term administration of CQ or HCQ rarely causes severe side effects
  • Short-term administration of CQ or HCQ rarely causes severe side effects
  • ...24 more annotations...
  • bone marrow suppression
  • cardiomyopathy
  • irreversible retinal toxicity
  • hypoglycaemia
  • daily doses up to 400 mg of HCQ or 250 mg CQ for several years are considered to carry an acceptable risk for CQ-induced retinopathies, with the exception of individuals of short stature
  • chronic CQ or HCQ therapy be monitored through regular ophthalmic examinations (3–6 month intervals), full blood counts and blood glucose level checks
  • long-term HCQ exposure, skeletal muscle function and tendon reflexes should be monitored for weakness
  • both CQ and HCQ, specific caution is advised in patients suffering from impaired hepatic function (especially when associated with cirrhosis), porphyria, renal disease, epilepsy, psoriasis, glucose-6-phosphate dehydrogenase deficiency and known hypersensitivity to 4-aminoquinoline compounds
  • CQ and HCQ can effectively increase the efficacy of various anti-cancer drugs
  • CQ can prevent the entrapment of protonated chemotherapeutic drugs by buffering the extracellular tumour environment and intracellular acidic spaces
  • This study recommends an adjuvant HCQ dose of 600 mg, twice daily.
  • HCQ addition was shown to produce metabolic stress in the tumours
  • HCQ (400 mg/day)
  • important effects of CQ and HCQ on the tumour microenvironment
  • The main and most studied anti-cancer effect of CQ and HCQ is the inhibition of autophagy
  • the expression levels of TLR9 are higher in hepatocellular carcinoma, oesophageal, lung, breast, gastric and prostate cancer cells as compared with adjacent noncancerous cells, and high expression is often linked with poor prognosis
  • TLR9-mediated activation of the NF-κB signalling pathway and the associated enhanced expression of matrix metalloproteinase-2 (MMP-2), MMP-7 and cyclo-oxygenase 2 mRNA
  • HCQ can activate caspase-3 and modulate the Bcl-2/Bax ratio inducing apoptosis in CLL, B-cell CLL and glioblastoma cells
  • In triple-negative breast cancer, CQ was shown to eliminate cancer stem cells through reduction of the expression of Janus-activated kinase 2 and DNA methyl transferase 1 [106] or through induction of mitochondrial dysfunction, subsequently causing oxidative DNA damage and impaired repair of double-stranded DNA breaks
  • CQ or HCQ would be considered for use in combination with immunomodulation anti-cancer therapies
  • Therapies used in combination with CQ or HCQ include chemotherapeutic drugs, tyrosine kinase inhibitors, various monoclonal antibodies, hormone therapies and radiotherapy
  • Most studies hypothesise that CQ and HCQ could increase the efficacy of other anti-cancer drugs by blocking pro-survival autophagy.
  • daily doses between 400 and 1200 mg for HCQ are safe and well tolerated, but two studies identified 600-mg HCQ daily as the MTD
  • HCQ is often administered twice daily to limit plasma fluctuations and toxicity
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