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Nathan Goodyear

Sarcopenia and Age-Related Endocrine Function - 0 views

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    Good discussion of sarcopenia.  They article looked at the evidence of Testosterone and found the evidence pointed to improved lean muscle mass; but not a direct cause effect of low T and sarcopenia.
Nathan Goodyear

Frontiers | Sarcopenia and Androgens: A Link between Pathology and Treatment | Endocrin... - 0 views

  • sarcopenia induces a change in the proportion of skeletal muscle fibers, inducing a shift from type II (fast) to type I (slow) fibers as well as preferential loss of type II fibers
  • testosterone stimulates protein synthesis by both a short-term mechanism-rapid activation of pre-existing components of the translational apparatus- and a long-term mechanism-increase in cell or tissue capacity at the protein synthesis level leading to increase in ribosome quantity
  • testosterone induces an increase in cross-sectional area (CSA) in type I and II muscle fibers and in myonuclear quantity, indicating that testosterone exerts more of a hypertrophic than a hyperplasic effect on skeletal muscle
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    good discussion of sarcopenia.
Nathan Goodyear

Hormonal and lifestyle determinants of appendicular skeletal muscle mass in men: the MI... - 0 views

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    muscle loss, sarcopenia is a significant marker of poor health in men.  This study of 845 men age 45-85 finds that low Testosterone, low vitamin D, low physical activity, smoking, and thin body build are associated with sarcopenia in men.
Nathan Goodyear

Testosterone Supplementation Reverses Sarcopenia in Aging through Regulation of Myostat... - 0 views

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    animal study finds Testosterone reversed age associated sarcopenia.
Nathan Goodyear

Weekly Versus Monthly Testosterone Administration on Fast and Slow ... - PubMed - NCBI - 0 views

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    Weekly Testosterone injections increase type 1 slow muscle fibers more than type II fast twitch muscle fibers compared to monthly injections.  The study looked at older men with sarcopenia and low T.
Nathan Goodyear

Relationship between Low Free Testosterone Levels and Loss of Muscle Mass : Scientific ... - 0 views

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    Study finds low free Testosterone and low calculated free Testosterone was associated with sarcopenia in Japanese men.  This association was not found with Total Testosterone.
Nathan Goodyear

Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old ... - 0 views

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    8 weeks of resistance training in patients with sarcopenia and diabetes found to improve glycemic control
Nathan Goodyear

Changes in Weight, Body Composition, and Factors Influencing Energy Balance Among Preme... - 0 views

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    study finds weight gain in premenopausal breast cancer survivors on adjuvant chemo is due to sarcopenia.
Nathan Goodyear

Testosterone levels improve in obese men following a common weight-loss operation: Slee... - 0 views

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    The ignorance of this authors statements is unmeasurable.  Numerous other studies have shown weight loss in men with obesity is associated with increased Testosterone production.  My book highlights the mechanism by which adipose tissue decreased Testosterone production.  The author was quoted as pointed to no Testosterone replacement (even if levels are low????) despite the evidence that Testosterone will improve glucose metabolism, build muscle (reverse sarcopenia obesity), improve cholesterol metabolism,  and significantly aid Diabetes control just to name a few; yet the author says, give surgery instead.  I am sure the author is a surgeon and thus bias might, just might, be present.
Nathan Goodyear

Relationship between low free testosterone levels and loss of muscle mass. - PubMed - NCBI - 0 views

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    low free Testosterone associated with muscle loss in men compared to no association with total Testosterone in Japanese men.
Nathan Goodyear

International Journal of Obesity - Identification of skeletal muscle mass depletion acr... - 0 views

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    good article to review the components of body composition.
Nathan Goodyear

Sarcopenic obesity - definition, etiology and consequences - 0 views

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    good discussion of sarcopenic obesity
Nathan Goodyear

A randomized trial of adjunct testosterone for cancer‐related muscle loss in ... - 0 views

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    Testosterone found to improve QOL measures in patients with cancer cachexia.
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