This study proves the problems rampant in science today. This study looked at older men with mobility limitations: safe to say, not optimal health. They give 10 grams of testosterone daily to these men. Physiologic doses are 5-10 mg. And they are surprise that there is an increase in side effects, here in this study CVD. They did look at cytokines, I'll give them that; but they did not look at aromatase activity and E2, E1 levels which have been shown to be the driving forces behind these inflammatory cytokines in men. Testosterone has in fact been shown to downregulate these inflammatory cytokines. Poor study. No conclusion can be taken from this study.
current vitamin B12 recommendations are too low. Proper vitamin B12 biomarker testing reveals this fact. The problem is most people fall prey to the lack of knowledge behind simple serum levels. Simple B12 serum levels are woefully inadequate. Insurance would rather one stay with inadequate testing to save money, rather than actually read the science to learn about new testing.
could the flu vaccine cause a short-term increase in cardiovascular event risk? According to this study yes. So, with a recent study showing no benefit in children and adults, then with this finding of increased arterial dysfunction, increased CRP and fibrinogen, and increased LDL oxidation...why would an adult get the flu vaccine???
The focus should be on what the science shows, not an individuals bias!
Another study supports saliva hormone testing. This study involved 2,722 individuals and tested estradiol, progesterone, DHEA and testosterone in men and women. All of these are sex hormones. Someone needs to tell the insurance companies that the overwhelming evidence supports saliva hormone testing. But, that would mean they are even interested in the science.
This is what amounts to science? As if high estrogen production from overdosing Testosterone only results in gynecomastia. This study is trying to validate doping utilizing testosterone by saying that no one listed gynecomastia as the reason for AI therapy?!?! No evaluation on PSA, TNF-alpha, CRP...was done. This study is worthless.
Recurrent early pregnancy losses can be prevented not with provera, not with progestin, but with progesterone. The use of progesterone by the functional medicine movement has long been advocated and supported in the science; now the allopathic medicine will try to claim it as its own.
Exercise is not only safe in pregnancy, it is good for the pregnancy and the baby. This idea that pregnancy is a disease or a condition has got to stop; science continues to prove that is not the case.
LC-MS/MS overcomes the limitations of immunoassays in hormone testing. LC-MS/MS is the new gold standard with sensitivity, specificity, and ease second to none. LC-MS/MS is the bench science now coming to the practice of medicine.
Study finds negligible effect of Testosterone therapy (4.8 mg) on PSA. The study consisted of several phases, the longest being 6 years. However, each phase the parcipitants significantly declined. The long held belief that Testosterone and DHT promote an increase in PSA is just not supported in the science. In fact, aromatase knockout mice don't develop prostate cancer, only BPH.
This is a good review of the biochemistry behind Hg effects on biochemistry. This article tries to review the data objectively to help analyze the Hg-autism link. Too much political polarization of this issue has occurred. Politics has no place in this debate--only a debate of the science!
I find this study a good example of the distortion in medical science. This study looked at lifestyle changes as its effect on hormones and glucose regulation. This study found a decrease in estrogen, decrease in DHEA, and an increase in SHBG. However, they included metformin therapy in the lifestyle arm of the study. What about metformin is "lifestyle"?
Yale study finds estrogen therapy in improves health in women ages 50-59. The problems with hormone therapy is synthetics and overdosing. The problem with the WHI was they used medroxy progesterone acetate--a synthetic progestin. That is not progesterone. This study estimated that 91,000 + died due to the uneducated view that estrogen HRT is dangerous. What is dangerous is leaving the HRT and BHRT recommendations to those with conflicts of interest and a lack of knowledge of the science.
Men with Metabolic Syndrome have lower Total Testosterone values. Symptoms correlated with age: older men associated with increased symptoms. This study only found lot T at 6.5%. The authors in this study have come up with a new box--andropenia. I don't know what the heck that is and how that helps clients. If symptoms are present and if levels are on the decline, then symptomatic hypogonadism is present. I know the logic seems simple, but it appears hard to follow in the science. I don't see this any different then type II diabetes. At 126 you have diabetes, but at 125, we don't know what to do with you but see us next year and you will have diabetes and we will know what to do because you are in the box of diabetes.