Group items tagged

bias is rampant in medical research.

good read on clinical application of BIA in the clinical setting.

good review of endocannabinoid system. More importantly, this article reveals the Bias present in the pharmaceutical arena, as it relates to their drug research.

good review on the science behind BIA or bioelectrical impedance analysis.

Meta-analysis finds bias in industry studies versus independent studies.  No surprise there.   Testosterone in this meta-analysis was found to aid sexual dysfunction in men with hypogonadism.

could the flu vaccine cause a short-term increase in cardiovascular event risk?  According to this study yes.  So, with a recent study showing no benefit in children and adults, then with this finding of increased arterial dysfunction, increased CRP and fibrinogen, and increased LDL oxidation...why would an adult get the flu vaccine??? The focus should be on what the science shows, not an individuals bias!

This study, a review of 16 articles, found little scientific support for the "blood type" diet.  This is why I have not made this recommendation to our clients--no real data to support this diet.   One question, is what was the eligibility criteria for inclusion of the studies.  Only one out of the 16 was selected.  Inclusion/exclusion criteria in these studies can brian bias.

could the anti-depressant industry in children and adolescents be a scam?  A review of the evidence finds very low quality of evidence with > 56% of the studies being funded by the industry itself; can you say conflict of interest or potential bias?  Review finds evidence only that fluoxetine is more effective than placebo in children and adolescents with depression.

Study was undertaken in China due to alarming increase in breast cancer in Chinese women. This meta-analysis of 36 articles found a 44% increase in breast cancer with one abortion.  This increased to 76% at 2 and 89% at 3 abortions respectively.   This study is very important and previous criticisms of prior studies linking abortion to breast cancer has been reporting bias.  In China, due to the one child policy, abortion is a way of life and there is no cultural shame involved.

Absolute must read!  Science. That is what physicians are.  Eliminate politics and bias.  Aluminum, common adjuvant in vaccines and well known neurotoxin, has been linked to post vaccine macrophagic myofascitis.  Now, world experts have placed it at the forefront of a new created syndrome "ASIA" which is autoimmune/inflammatory syndrome induced by adjuvants.  

Study finds no worsening in cardiovascular biomarkers in women on Testosterone.  The women in this study were chose due to low Testosterone.  Testosterone was given IM at 4 different doses.  This is in contrast to other studies that have looked at endogenous Testosterone level.  Studies have shown increasing endogenous T levels in women is associated with increased CVD.  Studies on exogenous are lacking.  This points to limited risk associated with CVD and T therapy in women.   One caveat.  Two of the authors of this study have ties to the maker of the Testosterone enanthate used in this study.  Why is this important?  Prior studies have shown significant decrease in adverse event reporting in those funded by pharma--bias.

24 week study of 71 women post-hysterectomy finds no increase in cardiovascular biomarkers.  Several problems with this study.  First, there was a large drop out--24%.  Second and most important, the women were pretreated with estrogen prior to Testosterone therapies were initiated.  Other studies have proposed that this protects cardiovascular risk in women on Testosterone.  Previous studies show increasing endogenous Testosterone is associated with increasing cardiovascular disease in women.   This study would be much better if no estradiol was prescribed.  That would give an unbiased view of Testosterone in post-hysterectomy women.  Not much can be taken from this study. If you doctor doesn't know this, find another doctor.  Inherent bias in this study as ties to the manufacturer of the Testosterone was disclosed. This study point to the inherent flaws in so much of the medical literature today.  Most would read the headlines and read no further, but the "further" dispels the headline as flawed.

Only abstract available.  Meta-analysis of Testosterone therapy in post-menopausal women finds significant bias, some improvement in sexual function and cholesterol levels, yet safety and long-term data is significantly lacking.  Take this with studies on endogenous Testosterone in women, significant caution needs to be followed with Testosterone in women. Only abstract available here.

Black Spanish radish found to up regulate phase I/II liver detoxification with tylenol exposure.  Now, this was sponsored by a maker of a herbal product so that would include some potential bias.

The ignorance of this authors statements is unmeasurable.  Numerous other studies have shown weight loss in men with obesity is associated with increased Testosterone production.  My book highlights the mechanism by which adipose tissue decreased Testosterone production.  The author was quoted as pointed to no Testosterone replacement (even if levels are low????) despite the evidence that Testosterone will improve glucose metabolism, build muscle (reverse sarcopenia obesity), improve cholesterol metabolism,  and significantly aid Diabetes control just to name a few; yet the author says, give surgery instead.  I am sure the author is a surgeon and thus bias might, just might, be present.

New cohort study finds increased risk of Testosterone in men > 65 and those : these are based in marketing-based medicine not evidence based medicine.

Phase angle is a useful tool in assessing cell death/health balance, as well as cell membrane.

autoimmune disease sexual preference appears to have Gut origins.