Skip to main content

Home/ Dr. Goodyear/ Group items tagged Polycystic

Rss Feed Group items tagged

Nathan Goodyear

Androgen therapy and atherosclerotic cardiovascular disease - 0 views

  • In women, it is much clearer that androgen excess is linked to the burden of CVD risk factors
  • insulin resistance is a consequence of androgen effects
  • Women with PCOS have a sustained exposure to high physiologic androgen levels. This condition is associated with endothelial dysfunction, obesity and metabolic abnormalities such as insulin resistance and dyslipidaemia
  • ...4 more annotations...
  • Further evidence of a link between high androgen levels and CVD or CVD risk factors is observed in women with polycystic ovary syndrome (PCOS)
  • For T treatment in aging women, the current data would suggest androgen excess has adverse effects on CVD risk factors, especially in women with diabetes
  • androgen use and abuse is increasing in our society, either for therapeutic or recreational reasons
  • For men, exogenous T treatment appears largely beneficial
  •  
    I love these review articles that highlight the metabolic differences of hormones in women versus men.  The medical community as a whole doesn't seem to get this at all.  The marketing-based medical community doesn't either.
Nathan Goodyear

The Effect of Atorvastatin and Atorvastatin-Ezetimibe Combination T... - PubMed - NCBI - 0 views

  •  
    Cholesterol lowering drug, atorvastatin, lowers androgen levels in women with PCOS.  The same has been shown in men.
Nathan Goodyear

N-Acetylcysteine for Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis o... - 0 views

  • compared effects of NAC with placebo or metformin in women with PCOS
  • NAC significantly improved rates of live births and spontaneous ovulation compared to placebo in women with PCOS
  • we found no evidence of effects of NAC on improving menstrual regularity, acne, hirsutism, BMI, fasting insulin, fasting glucose, or HOMA-IR
  • ...3 more annotations...
  • NAC was not associated with greater benefits to metformin for improving pregnancy rate, spontaneous ovulations, and menstrual regularity
  • Metformin also improved the BMI, total testosterone, insulin level, and lipid levels compared to NAC
  • All the studies were of short duration (three months)
  •  
    Data review finds NAC improves pregnancy rates and ovulation rates in women with PCOS against placebo.  Meta-analysis revealed limited studies on the topic.  When compared to metformin, there was no difference found.  Though, one wonders if attacking insulin resistance through proper diet and additional neutraceutical approach would negate that.  The reason?  NAC and metformin are working in different biochemical pathways.  The authors here seem to not realize this. It appears that they think NAC and metormin are both working in the same manner, but they don't.  The fact that there is still benefit found compared to placebo, despited the authors lack of understanding of what NAC is and does is a positive.
Nathan Goodyear

High prevalence of Hashimoto's thyroiditis in patients with polycystic ovary syndrome: ... - 0 views

  •  
    Hashimoto's thyroid disease associated with PCOS in women; this was found to be associated with an increased Estradiol:Progesterone ratio.  
star yu

How to Avoid Dialysis for PKD Stage 3 Patients - 0 views

  •  
    How to avoid dialysis for PKD stage 3 patients? As we all know, Polycystic Kidney Disease is a kind of genetic kidney disease, with the disease goes worse, doctors will recommend dialysis to patient.
Nathan Goodyear

http://pediatrics.aappublications.org/content/pediatrics/136/6/1154.full.pdf - 0 views

  •  
    good review of the physiology behind adolescent PCOS.  Though I hate this term because it treats PCOS as a diagnostic disease when it is simply a metabolically induced hormone balance.
fnfdoc

Causes And Symptoms Of PCOS | Your Health Our Priority - 0 views

  •  
    PCOS is a disease of the female reproductive system that is characterized by hairiness, infrequent or heavy periods, skin disorders and infertility. Its symptoms and causes need immediate medical care as it can be deadly.
Nathan Goodyear

Serum LBP Is Associated with Insulin Resistance in Women with PCOS - 0 views

  •  
    increased LBP associated with PCOS through insulin resistance.
Nathan Goodyear

Age and BMI Adjusted Comparison of Reproductive Hormones in PCOS - 0 views

  •  
    study of Saudi women with PCOS finds elevated LH/FSH ratio and elevated total Testosterone levels independent of age and weight; in addition, lower FSH, SHBG, and progesterone levels we found.
Nathan Goodyear

Thieme E-Journals - Hormone and Metabolic Research / Abstract - 0 views

  •  
    Short study found that Selenium improved pregnancy rate compared to placebo, reduced DHEA, hirsutism, CRP and MDA
« First ‹ Previous 81 - 90 of 90
Showing 20 items per page