Group items tagged

The women's health initiative dietary modification trial of almost 50,000 women found no association between a low fat diet and a reduction of colorectal cancer.  Translation: a low fat diet does not lower the risk of colorectal cancer.

NSAIDS, such as motrin, appear to have a negative effect on overall health and function

Cohort study of 6 compounding pharmacies find BHRT improves mood in those clients taking BHRT.

New study reveals that statin drug of any kind increases the risk of type II diabetes by 48% in postmenopausal women

large study of 50,000 postmenopausal women found no significant reduction in CVD with a low fat diet.  The mean dietary time period was 8 years.

Premarin increases the risk of stroke in postmenopausal women.  The risk of hip fracture was reduced and no change in Coronary Heart disease was found.

Terrible study published in medical journal that provides no scientific valuable information

Higher vitamin D levels associated with decreased risk of cancer in women--67% decrease.

40 year study out of England finds no mortality benefit from mammograms screening.

BHRT shown to be significantly better for sexual  symptoms than with conventional HRT.  78% vs 33%.

Statin drugs shown to increase risk of Diabetes in postmenopausal women

women using statin therapy to lower cholesterol have increased type II Diabetes.  Variables were accounted for and this existed across all classes of statins.

Shorter telomere lengths associated with breast cancer.  But, longer telomere length may as well.

This was the WHI review of data as it pertains to dementia and cognitive decline in women.  The take home here is that the data provides little evidence for premarin with or without medroxyprogesterone acetate in > 65 for prevention of dementia.  However, this is in women > 65 and studies show that younger women do indeed receive benefit, especially in those with early ovary removal.  Another point here, MPA (medroxyprogesterone acetate) increases cognitive decline.  Just don't take MPA, it is a bad drug all the way around!

Estrogen with progestin worsens cognitive decline in women >65.  Little can be taken from this study other than, medroxyprogesterone acetate is a bad drug and should not be given to women for any purpose, especially in those >65.  One wonders if bioidentical, physiologic hormone replacement would have the same effect?  I doubt it.  The likely negative impact of hormones on the brain in women >65 is due to the negative effects of MPA, the change in inflammatory cytokines, and the change in receptors.

ER beta is a new potential mode of therapy in colon cancer.  ER beta stimulation has been shown to inhibit colon cancer cell growth.

Vasomotor symptoms (hot flashes and night sweats) is associated with increased cardiovascular risk in women.

Data review finds NAC improves pregnancy rates and ovulation rates in women with PCOS against placebo.  Meta-analysis revealed limited studies on the topic.  When compared to metformin, there was no difference found.  Though, one wonders if attacking insulin resistance through proper diet and additional neutraceutical approach would negate that.  The reason?  NAC and metformin are working in different biochemical pathways.  The authors here seem to not realize this. It appears that they think NAC and metormin are both working in the same manner, but they don't.  The fact that there is still benefit found compared to placebo, despited the authors lack of understanding of what NAC is and does is a positive.

High incidence of CIN-2 regression in young women with conservative management.

Study finds increased risk of diabetes in post menopause women on statin therapy.  The authors here propose it as a class effect but also is associated with increased dosing.