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Nathan Goodyear

Testosterone Treatment and Sexual Function in Older Men with Low Testosterone Levels: T... - 0 views

press.endocrine.org/...jc.2016-1645

low T low Testosterone Testosterone male hormones libido ED estradiol hormones

shared by Nathan Goodyear on 13 Jul 16 - No Cached
  • Nathan Goodyear on 13 Jul 16
     
    new study finds that men >65 with low libido and Testosterone levels < 275 increase sexual function with Testosterone therapy.  Only libido was improved; no benefit to erectile function was noted--note that is likely due to depleted NO.  Given time that should improve with he increase in NO synthase and thus NO.  I have a fault with on elf the comments on this study: they point out that increased free Testosterone and estradiol levels were associated with improved sexual activity.  This lacks an understanding of the physiology.  In men with low T > 65, the majority are dealing with inflammation and excess weight; all of which increase aromatase activity and thus estradiol activity.  This does not indicate that an increase in estradiol activity is associated with improved libido in men.  How can elevated estrogen levels lead to low T and then increase levels are associated with improved libido?  This is merely a reflection of the body's dysfunctional physiology.  This observation of increased estradiol by no means shows cause and effect.  Scientists need to due a better job in vetting what they write!
Nathan Goodyear

Peripheral mechanisms of erectile dysfunction in a rat model of chronic cocaine use. - ... - 0 views

www.ncbi.nlm.nih.gov/...17420087

ED cocaine eNOS NO nitric oxide

shared by Nathan Goodyear on 11 Aug 16 - No Cached
  • Nathan Goodyear on 11 Aug 16
     
    animal study finds that cocaine binge use associated with decreased eNOS expression in the penis.  This is consistent with the other very limited studies that show that cocaine decreases eNOS protein expression and thus NO.
Nathan Goodyear

Effects of Smoking on Plasma Testosterone Level and Erectile Function in Rats - Park - ... - 0 views

onlinelibrary.wiley.com/...abstract

smoking effects testosterone plasma erectile function ED

shared by Nathan Goodyear on 17 Feb 12 - No Cached
  • Nathan Goodyear on 17 Feb 12
     
    smoking reduces serum testosterone in rats.  The real question is what does it do to the salivary levels (tissue) and the metabolism of testosterone.
Nathan Goodyear

Bentham Science Publishers - 0 views

www.benthamdirect.org/...content.php

brain sex ED erectile dysfunction endothelial dysfunction hormone hormones inflammation

shared by Nathan Goodyear on 11 Jul 12 - No Cached
  • Gonadal, adrenal and neurosteroids
  • Nathan Goodyear on 11 Jul 12
     
    hormones are the link between the brain and sex for men?  Yes, but a little more complex than that: interaction between the immune system (inflammation) and the endocrine system (hormones).
Nathan Goodyear

International Journal of Impotence Research - Treatment of testosterone-induced gynecom... - 0 views

www.nature.com/...3901154a.html

arimidex anastrozole low T testosterone aromatase activity inhibition inhibitor impotence ED

shared by Nathan Goodyear on 26 Feb 12 - No Cached
  • Nathan Goodyear on 26 Feb 12
     
    arimidex, also known as anastrozole, is shown to be an effective aromatase inhibitor in men.  These case studies used arimidex to successfully stimulate testosterone production by limiting testosterone to estrogen production.  This was found to be useful in the treatment of gynecomastia.
Nathan Goodyear

Maternal amino acid supplementation ... [Front Biosci (Schol Ed). 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21196387

amino acid pregnancy

shared by Nathan Goodyear on 07 Mar 12 - No Cached
  • Nathan Goodyear on 07 Mar 12
     
    Amino acid supplementation and pregnancy.
Nathan Goodyear

Dramatic improvement in sexual function induced by... [J Sex Med. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22458365

oxytocin intranasal libido ED hormone hormones

shared by Nathan Goodyear on 29 Jul 13 - No Cached
  • Nathan Goodyear on 29 Jul 13
     
    limited study as it is a case study of 1.  However, there was improvement with libido, erection, and orgasm in this case study of 1 with intranasal oxytocin.
Nathan Goodyear

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1700586/pdf/brmedj02278-0080b.pdf - 0 views

www.ncbi.nlm.nih.gov/...brmedj02278-0080b.pdf

pesticide pesticides ED men male

shared by Nathan Goodyear on 17 Sep 14 - No Cached
  • Nathan Goodyear on 17 Sep 14
     
    case study from years ago that finds pesticide exposure caused impotence in 4 agriculture workers.  
Nathan Goodyear

A long-term, prospective study of the physiologic and behavioral effects of hormone rep... - 0 views

www.andrologyjournal.org/...297

low T testosterone ED erectile dysfunction

shared by Nathan Goodyear on 02 Mar 11 - No Cached
  • hese data support the hypothesis that androgen treatment increases nocturnal and spontaneous erections, and sexual interest, and has some capacity to improve mood.
  • Nathan Goodyear on 02 Mar 11
     
    testosteron in low Testosterone men improves symptoms
Nathan Goodyear

International Journal of Impotence Research - Clomiphene increases free testosterone le... - 0 views

www.nature.com/...3900981a.html

low T Testosterone ED erectile dysfunction climid

shared by Nathan Goodyear on 24 Jul 14 - No Cached
  • Nathan Goodyear on 24 Jul 14
     
    Nice study that looked at climid to restore HPA function and increase Testosterone stimulation and production.  This study also does a good job of reviewing the mechanisms of low T.  Low T is really a biomarker of poor health in men.
Nathan Goodyear

Effects of testosterone on neuronal nitric oxide synthase and tyrosine hydroxylase. - P... - 0 views

www.ncbi.nlm.nih.gov/...10415408

Testosterone low T low Testosterone NO nitric oxide NOS ED male hormones

shared by Nathan Goodyear on 18 Nov 15 - No Cached
  • Nathan Goodyear on 18 Nov 15
     
    Testosterone proposed to increase NOS
Nathan Goodyear

Nitric oxide mediated erectile activity is a testosterone dependent event: a rat erecti... - 0 views

www.ncbi.nlm.nih.gov/...8770664

low T low Testosterone NO NOS nitric oxide Testosterone ED men male hormones

shared by Nathan Goodyear on 18 Nov 15 - No Cached
  • Nathan Goodyear on 18 Nov 15
     
    Only abstract available here, but rat model finds Testosterone increased NO synthase activity in corpora cavernous. 
Nathan Goodyear

Erectile dysfunction and testosterone deficiency. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19011292

PDE5 PDE5 inhibitors PDE5I low T low Testosterone NO nitric oxide ED men hormones Testosterone

shared by Nathan Goodyear on 18 Nov 15 - No Cached
  • Nathan Goodyear on 18 Nov 15
     
    A high percentage of men that fail PDE5 therapy have low T and the addition of T therapy improves the effects of PDE5 therapy.  T provides a positive impact on NO synthase which increased NO, which PDE5 therapies must have to work.
Nathan Goodyear

EMAS position statement: Testosterone replacement therapy in the aging male 0f. - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...26614257

low T low Testosterone Testosterone testosterone therapy obesity metabolic syndrome diabetes ED osteoporosis male aging hormones

shared by Nathan Goodyear on 07 Dec 15 - No Cached
  • Nathan Goodyear on 07 Dec 15
     
    we need to get away from expert opinion statements like this. Not that their conclusions are incorrect; but it promotes laziness among physicians.  We physicians need to take control over the data by which we practice medicine and the only way we can do that is to read it.
Nathan Goodyear

Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction... - 0 views

onlinelibrary.wiley.com/...abstract

male hormones' hormones estradiol Testosterone sexual dysfunction ED erectile dysfunction

shared by Nathan Goodyear on 12 Oct 16 - No Cached
  • Nathan Goodyear on 12 Oct 16
     
    Men with sexual dysfunction found to have higher E:T ratio and higher Estradiol overall.  This was a retrospective study.
Nathan Goodyear

Dopamine and male sexual function. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11805404

dopamine ED erectile dysfunction erection

shared by Nathan Goodyear on 21 May 17 - No Cached
  • Nathan Goodyear on 21 May 17
     
    dopamine plays role in erections in men.
Nathan Goodyear

Treatment of Men for "Low Testosterone": A Systematic Review - 0 views

journals.plos.org/...article

low t low Testosterone Testosterone Testosterone therapy

shared by Nathan Goodyear on 11 Jan 17 - No Cached
  • Of 47 studies that assessed sexual function or satisfaction, 23 studies reported beneficial effects of testosterone treatment for at least 1 measure of sexual function or satisfaction,[6, 26, 35, 37, 40, 43–60] and 24 studies did not show testosterone-associated improvements in any sexual function endpoint
  • Of 31 studies that evaluated erectile function, 15 found no improvement with testosterone therapy
  • Twelve studies included men with ED; 8 found no benefit of testosterone over placebo
  • ...2 more annotations...
  • Of 23 studies that specifically reported changes in libido, 13 found that testosterone treatment increased libido,[26, 35, 37, 45, 46, 54, 56, 60, 63, 65, 70, 77, 79] eight found no effect,
  • Eleven studies used the Aging Males’ Symptoms scale, which includes 3 questions on libido and sexual function. Five studies found no difference between testosterone and placebo on total scores,[26, 54, 57, 72, 76] and 4 studies found a benefit of testosterone
  • Nathan Goodyear on 11 Jan 17
     
    A systemic review of Testosterone benefit in men stirs the pot.  I can't say that I agree with the majority of their conclusions.  What I do agree with them on is that the majority of men on Testosterone therapy likely don't need it and are simply using Testosterone as a drug.
thomaslist

Polo Ralph Lauren,Discount Polo Shirts For Men And Women - 0 views

www.poloralphlaurendiscount.us

https:__www.fjallravenbackpackus.com

shared by thomaslist on 06 May 22 - No Cached
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