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Nathan Goodyear

Chronic burnout, somatic arousal and elevate... [J Psychosom Res. 1999] - PubMed - NCBI - 0 views

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    This study showed that "burnout" was associated with elevated salivary cortisol and this could explain part of the pathophysiology of CVD in these individuals.  This is a great article that shows that stress is a physiologic response and it kills
Nathan Goodyear

Consequences of magnesium deficiency on the e... [J Am Coll Nutr. 1994] - PubMed - NCBI - 0 views

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    Magnesium deficiency in the face of stress increases the risk of CVD.
Nathan Goodyear

Low Grade Chronic Inflammation in Women with Polycystic Ovarian Syndrome - 0 views

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    Women with PCOS have associated increased inflammation.  This origin is primarily via adipose tissue and associate adipocytokines (TNF-alpha, and IL-6).  CRP elevation, as found in this study, is associated with increased CVD.
Nathan Goodyear

The polycystic ovary syndrome per se is not associated with increased chronic inflammation - 0 views

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    This study finds no association between PCOS and inflammation, when matched with age/BMI controls.  However, inflammation was associated with increased BMI.  Not all women with PCOS are overweight.  But, the majority are and this would contribute to inflammation and thus CVD.
Nathan Goodyear

Glutathione (GSH) improved haemostatic an... [Drugs Exp Clin Res. 1992] - PubMed - NCBI - 0 views

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    IV glutathione shown to reduce blood viscosity and platelet aggregation.  THis has major implications in atherosclerosis and CVD
Nathan Goodyear

Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction - NEJM - 0 views

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    NORVIT trial showed that vitamin B12, B6, and folic acid reduced homocysteine levels by 27%, however it did not lower MI, stroke,or mortality rate.  ONe variable to consider is the polypharmacy of the study group ie.  they were taking statins, beta blockers, diuretics, coumadin... so was the lack of change in mortality the result of polypharmacy?  And was the polypharmacy blocking the increased CVD risks associated with elevated homocysteine that would have been treatable with vitamin B12, B6, and folic acid.
Nathan Goodyear

Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease - NEJM - 0 views

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    Vitamin B12, B6, and folic acid shown to lower homocysteine levels and decreased the incidence of stroke.  However, overall mortality and CVD deaths were not.
Nathan Goodyear

Nutrition Journal | Full text | Homocysteine and reactive oxygen species in metabolic s... - 0 views

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    homocysteine contributes to atherogenesis and CVD via: increased ROS, induces endothelial dysfunction, increases platelete adhesion and thrombosis, increases smooth muscle cell proliferation, endothelial cell cytotoxicity, increases LDL oxidation, vasoconstriction, increased MCP-1 and IL-8, and induces endothelial HMG CoA reductase.
Nathan Goodyear

High serum testosterone is associated with... [J Am Coll Cardiol. 2011] - PubMed - NCBI - 0 views

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    Testosterone inversely associated with CV events in men.  Low T is not just for ED, but should be a part of CVD prevention.
Nathan Goodyear

JAMA Network | JAMA: The Journal of the American Medical Association | Effects of Prote... - 0 views

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    In this study, a high carbohydrate diet was replaced with a diet higher in monosaturated fats.  The result was: a lower carb diet with resultant increase in monosaturated fats resulted in a reduction in triglycerides, reduction in systolic B/P, increase in HDL, and resultant decrease in CVD risk
Nathan Goodyear

JAMA Network | JAMA: The Journal of the American Medical Association | Low-Fat Dietary ... - 0 views

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    large study of 50,000 postmenopausal women found no significant reduction in CVD with a low fat diet.  The mean dietary time period was 8 years.
Nathan Goodyear

The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia - Houston - 2012... - 0 views

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    Dr. Mark Houston discusses the use of neutraceuticals to treat dyslipidemia and CVD.
Nathan Goodyear

http://circ.ahajournals.org/content/109/17/2074.full.pdf - 0 views

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    lower Free Testosterone and increased Estradiol through aromatase activity is associated with increased atherosclerosis.  This was monitored with Carotid intima-media thickness.  This study found an increase associated with low free Testosterone and increased free estradiol levels independent of other CVD variables.
Nathan Goodyear

http://news.a4m.com/issues/20140211/Testosterone-and-Heart-Disease.pdf?utm_source=web_e... - 0 views

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    Excellent review of the current literature on Testosterone and cardiovascular disease as well as a brief discussion of the flaws in the recent published articles pointing to increased CVD with Testosterone therapy.
Nathan Goodyear

Testosterone, SHBG and cardiovascula... [Int J Impot Res. 2010 Mar-Apr] - PubMed - NCBI - 0 views

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    Higher Testosterone and low SHBG  in postmenopausal women is associated with increased CVD risk
Nathan Goodyear

Higher Serum Testosterone Concentration in Older Women is Associated with Insulin Resis... - 0 views

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    This study found that increasing Testosterone, as determined by serum, is associated with increased CVD, insulin resistance, and metabolic syndrome in postmenopausal women.  I believe that this massive Testosterone doping campaign that we are seeing in men and women is following the same patter seen with premarin and provera. 
Nathan Goodyear

Endogenous androgen levels and cardiovascular risk profile i... : Menopause - 0 views

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    Study finds low SHBG associated with increased CRP and CVD in post menopause women.  No significant association with androgens and CRP were found.
Nathan Goodyear

Androgens in relationship to cardiovascular risk factors in the menopausal transition, ... - 0 views

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    Increasing androgens, male hormones, may be associated with the increased risk of CVD found in post menopausal women.  Other variables also need to be included ie. fat, insulin resistance...
Nathan Goodyear

Testosterone, SHBG and cardiovascular health in postmenopausal women - 0 views

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    Master's thesis reviews Testosterone therapy in women.  The evidence is poor.  What is seen is that low SHBG and increasing Testosterone in the long term appears to be associated with adverse CV effects. Otherwise, the effects of Testosterone are negligible if negative at all.   High dose studies did find increased CVD in women. The dosing here was at 40 mg.
Nathan Goodyear

Access : Testosterone, SHBG and cardiovascular health in postmenopausal women : Interna... - 0 views

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    Review finds that low SHBG and higher Testosterone levels are associated with increased CVD risk in post menopausal women.  Exact relationship is undetermined.
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