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Nathan Goodyear

Reversible infertility in male coeliac patients. - 0 views

www.ncbi.nlm.nih.gov/...PMC1681902

infertility male men hormone hormones celiac disease celiac disease gluten

shared by Nathan Goodyear on 28 Jul 14 - No Cached
  • Nathan Goodyear on 28 Jul 14
     
    Small study of 40 men with Celiac disease found to have improved sperm count and motility following elimination of gluten 
fnfdoc

Home Remedies For PCOS | Your Health Our Priority - 0 views

www.fnfdoc.com/...home-remedies-pcos

Home Remedies For PCOS

shared by fnfdoc on 09 May 18 - No Cached
  • fnfdoc on 09 May 18
     
    PCOS is a serious disease of the female reproductive tract identified by male pattern baldness, hirsutism, sleep apnea and infertility. Unfortunately, there is no cure for it. However, some home remedies can help ease the symptoms.
Nathan Goodyear

Review of health risks of low testosterone and testosterone administration - 0 views

www.ncbi.nlm.nih.gov/...PMC4391003

low Testosterone low T Testosterone men male hormone hormones health

shared by Nathan Goodyear on 28 Apr 15 - No Cached
  • Hypogonadism may be defined either as serum concentration of T (either total T, bioavailable T or free T) or as low T plus symptoms of hypogonadism
  • The Baltimore Longitudinal Study on Aging reported the incidence of total serum T < 325 ng/dL to be 20% for men in their 60s, 30% for men in their 70s and 50% for men over 80
  • The Massachusetts Aging Male Study reported that 12.3% of men aged 40 to 70 had a total serum T of < 200 ng/dL with 3 or more symptoms of hypogonadism
  • ...19 more annotations...
  • The Boston Area Community Health Study reported that 5.6% of men aged 30 to 70 were hypogonadal, as defined by total serum T < 300 ng/dL; or, free serum T < 5 ng/dL plus 3 or more symptoms of hypogonadism
  • In a health screening project among 819 men in Taiwan, the prevalence of hypogonadism (total serum T < 300 ng/dL) ranged from 16.5% for men in their 40s, 23.0% for men in their 50s, 28.9% for men in their 60s, and 37.2% for men older than 70 years of age
  • The prevalence of hypogonadism among men in Taiwan is higher than the prevalence reported in the Massachusetts Male Aging Study
  • CAG repeat sequence, within the androgen receptor (AR). Rajender et al[12] reviewed over 30 studies on the AR trinucleotide repeat and infertility
  • suggestion that CAG repeat length may determine androgen responsiveness, this issue is not clearly settled
  • reported prevalence of low T in older men range from 5.6% to 50%
  • Those in the hypogonadal group (n = 4269) had direct health care costs, that exceeded the eugonadal group (n = 4269) by an average of $7100 over the course of the observation window
  • higher economic burden and presence of co-morbidities for hypogonadism
  • minor to moderate improvements in lean mass and muscle strength
  • increased bone mineral density
  • modest enhancement in sexual function
  • reduced adiposity
  • lessening of depressive symptoms
  • Meta-analyses of clinical TRT trials as of 2010 have identified three major adverse events resulting from TRT: (1) polycythemia; (2) an increase in prostate-related events; and (3) and a slight reduction in serum high-density lipoprotein (HDL) cholesterol
  • polycythemia (> 3.5-fold increase in risk
  • TRT produced a 40% prostate enlargement in older hypogonadal male Veterans over 12 mo
  • no published analysis has reported measurable increases in prostate cancer risk or Gleason score in men undergoing TRT, or in hypogonadal men with a history of prostate cancer undergoing TRT
  • the prostate which highly expresses the type II 5α-reductase enzyme. Inhibition of this enzyme via finasteride (a type II 5α-reductase inhibitor) or dutasteride (a dual type I and II 5α-reductase inhibitor) reduces circulating DHT 50%-75% and > 90%, respectively[47], and reduces prostate mass[48] and prostate cancer risk
  • Normally estradiol partially regulates testosterone levels, at the hypothalamus, blunting LH and FSH release from the pituitary. As a selective estrogen receptor modulator, CC interrupts this pathway, and consequently there is a greater stimulation for the production of testosterone in Leydig cells
    • Nathan Goodyear
      Nathan Goodyear on 28 Apr 15
       
      this would only apply if E1 and/or E2 levels were elevated, which the authors make no mention of.
  • Nathan Goodyear on 28 Apr 15
     
    to be read
Nathan Goodyear

Estrogens in Men: Clinical Implications for Sexual Function and the Treatment of Testos... - 0 views

onlinelibrary.wiley.com/...abstract

men male testosterone estrogen estrone estradiol low T low testosterone testosterone deficiency

shared by Nathan Goodyear on 13 Jun 12 - No Cached
  • Nathan Goodyear on 13 Jun 12
     
    Several flaws with this study. First, the majority of testing done in the meta-analysis was serum--unreliable.  Second, this study flies in the face of many other studies that have shown elevated estrogens contribute to low testosterone in men.  Third, this flies in the face of observation.  I see over and over again, by lowering a male's estrogen level, he in turn will start producing more Testosterone.  And finally, the environmental xenoestrogens have helped to contribute to a all time low of testosterone/infertility rate in men today.
Nathan Goodyear

Exogenous testosterone: a preventable cause of male infertility - Crosnoe - Translation... - 0 views

www.amepc.org/...3145

low T Testosterone low T low Testosterone hormone hormones fertility infertility hypogonadism Hypogonadotropic hog human chorionic gonadotropin clomid

shared by Nathan Goodyear on 03 Aug 14 - No Cached
  • Nathan Goodyear on 03 Aug 14
     
    very nice case review and discussion of the treatment of low T and low sperm count in men desiring preservation of fertility.  Clomid and HCG are viable options to increase endogenous Testosterone production, though both work via different mechanisms.
Nathan Goodyear

http://www.iasj.net/iasj?func=fulltext&aId=53034 - 0 views

www.iasj.net/iasj

Testosterone leptin obesity hormone hormones men male

shared by Nathan Goodyear on 22 Oct 14 - No Cached
  • Nathan Goodyear on 22 Oct 14
     
    Study of infertile, obese men found negative correlation between leptin and Testosterone.
Nathan Goodyear

Journal of Endocrinological Investigation - 0 views

www.jendocrinolinvest.it/...abstract.cfm

BMI low T men male infertility

shared by Nathan Goodyear on 28 May 13 - No Cached
  • Nathan Goodyear on 28 May 13
     
    Study finds that BMI is related to penile length
Nathan Goodyear

Decline in semen quality among fertile men in P... [N Engl J Med. 1995] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7816062

men decline declining sperm count number male low T testosterone infertility

shared by Nathan Goodyear on 26 Oct 12 - No Cached
  • Nathan Goodyear on 26 Oct 12
     
    Decline in concentration, function and morphological normal sperm in young men in Paris.  This was a 20 year study.  There was no reduction in semen volume.
Nathan Goodyear

Urinary bisphenol A, phthalates, and couple fecundity: the Longitudinal Investigation o... - 0 views

www.fertstert.org/...abstract

xenoestrogens phthalates fertility infertility male men toxins

shared by Nathan Goodyear on 03 Mar 14 - No Cached
  • Nathan Goodyear on 03 Mar 14
     
    Study finds phthalate exposure associated with a 20% decline in fertility in men not women.
Nathan Goodyear

Semen analysis and sperm function tests: How much to test? - 0 views

www.ncbi.nlm.nih.gov/...PMC3114587

semen analysis male infertility

shared by Nathan Goodyear on 30 Sep 13 - No Cached
  • Nathan Goodyear on 30 Sep 13
     
    good review of the data behind semen analysis and what is important to evaluate.
Nathan Goodyear

Factors affecting spermatogenesis upon gonadotropi... [Andrology. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25271205

hypogonadotropic hypogonadism azoospermia Testosterone male infertility men hormone hormones GnRH gonadotropins spermatogenesis

shared by Nathan Goodyear on 06 Oct 14 - No Cached
  • Nathan Goodyear on 06 Oct 14
     
    Previous Testosterone therapy did not effect Gonadotropin therapy for azoospermia in men with hypogonadotropic hypogonadism.  Gonadotropin therapy was quite successful in generating spermatogenesis in this meta-analysis.
Nathan Goodyear

Chronic lead exposure may be associated with erect... [J Sex Med. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17727353

lead Pb exposure ED CVD men male infertility erectile dysfunction

shared by Nathan Goodyear on 10 Jun 13 - No Cached
  • Nathan Goodyear on 10 Jun 13
     
    chronic lead exposure associated with ED in men.  As lead is a contributor to CVD, logically, this is not a surprise.
Nathan Goodyear

The impact of male overweight on semen quality and outcome of assisted reproduction Tho... - 0 views

www.ajandrology.com/article.asp

infertility BMI sperm count sperm concentration sperm motility

shared by Nathan Goodyear on 23 Sep 14 - No Cached
  • Nathan Goodyear on 23 Sep 14
     
    Abstract only. Study in men seeking reproductive assistance found that increasing BMI had no negative impact on sperm concentration, sperm count, motility and seminal volume. 
Nathan Goodyear

Bisphenol A and Reproduction, January 5, 2011, Friedrich 305 (1): 28 - JAMA - 0 views

jama.ama-assn.org/...28.2.short

BPA plastics toxins reproduction men male infertility

shared by Nathan Goodyear on 30 Jun 11 - No Cached
  • Nathan Goodyear on 30 Jun 11
     
    BPA from plastics known to cause reproductive problems in humans, now shown to cause sterility, suggesting mode of action
Nathan Goodyear

http://gut.bmj.com/content/23/7/608.full.pdf - 0 views

gut.bmj.com/...608.full.pdf

celiac disease celiac disease hypogonadism low T Testosterone sperm infertility men male hormone hormones

shared by Nathan Goodyear on 28 Jul 14 - No Cached
  • Nathan Goodyear on 28 Jul 14
     
    low Testosterone and abnormal sperm morphology and motility found to be associated with Celiac disease with men in small study.  
Nathan Goodyear

Testosterone Deficiency, Cardiac Health, and Older Men - 0 views

www.ncbi.nlm.nih.gov/...PMC4000629

low T low Testosterone hypogonadism men male hormone hormones Testosterone therapy disease diabetes metabolic syndrome osteoporosis HIV infertility opiates

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • 2.1 standard deviations in total testosterone was associated with a 25% increase in mortality
  • Erectile dysfunction is an established marker for future cardiovascular risk and the major presenting symptom leading to a diagnosis of low testosterone
  • There is a considerable body of evidence that low testosterone is associated with increased cardiovascular and cancer mortality
  • ...1 more annotation...
  • There is considerable evidence of modest cardiac and metabolic benefits that are shown to reduce cardiovascular risk plus sexual, mood, and quality of life changes associated with restoring testosterone levels
  • Nathan Goodyear on 27 Jan 15
     
    low Testosterone is associated with increased mortality in men and Testosterone therapy in men with low T is associated with a reduction in mortality in men.
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