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Nathan Goodyear

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fa... - 0 views

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    2008 article from diabetes.  This article supports metabolic endotoxemia arising out of the gut.  High fat diet intake results in disrupted gut flora, resulting in increrased LPS release, resulting in inflammation, leads to leaky gut, systemic endotoxemia, inflammation, and thus metabolic dysfunction: see obesity, DM..
Nathan Goodyear

Tight Junctions, Intestinal Permeability, and Autoimmunity Celiac Disease and Type 1 Di... - 0 views

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    this study from 2009 showed how disrupted/imbalanced gut flora leads to leaky gut.  This case, high bacteroides relative to bifidobacterium and lactobacillus resulted in disruption of the zonulin pathway and thus lncreased intestinal permeability.
Nathan Goodyear

Figure 2 : Targeting gut microbiota in obesity: effects of prebiotics and pro... - 0 views

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    nice diagram of proposed mechanism of how diet and gut microbiota can influence the production of PPAR-gamma inducing growth of adipose tissue.  Also proposes how LPS and the endocannabinoid system contributed to a leaky gut and thus the proposed "metabolic endotoxemia"
Nathan Goodyear

Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeabili... - 0 views

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    LPS increases break in tight junctions, leaky gut, to increase TLR4 expression and signaling.
Nathan Goodyear

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic O... - 0 views

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    prebiotics found to increase leptin sensitivity, improved glucose metabolism, lipid metabolism, reduced inflammation and improved leaky gut.  The probiotics increased the bifidobacterium species versus a decrease in the Firmicutes phyla.
Nathan Goodyear

ARTICLES | Physiological Reviews - 0 views

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    good review on zonulin, leaky gut, and disease.
Nathan Goodyear

The nutriceutical bovine colostrum truncates the increase in gut permeability caused by... - 0 views

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    colostrum improves gut permeability, and may improve performance and prevent injuries in athletes
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