Group items tagged

Zonulin and autoimmune disease

Increased Zonulin as a result of GI inflammation increases gut permeability and is associated with increased disease potential

Good review of zonulin regulation and intestinal permeability

good review on zonulin, leaky gut, and disease.

this study from 2009 showed how disrupted/imbalanced gut flora leads to leaky gut.  This case, high bacteroides relative to bifidobacterium and lactobacillus resulted in disruption of the zonulin pathway and thus lncreased intestinal permeability.