Vitamin D and breast cancer.
Bertone-Johnson ER.
Ann Epidemiol. 2009 Jul;19(7):462-7. Epub 2009 Feb 20. Review.
PMID: 19230714
Though the relationship between vitamin D and breast cancer remains unclear, a growing body of evidence suggests that vitamin D may modestly reduce risk. A large number of in vitro studies indicate that vitamin D can inhibit cell proliferation and promote apoptosis and cell differentiation in breast tumor tissue. Results from analytic studies of sunlight exposure and dietary intake have been inconsistent but together generally support a modestly protective role of vitamin D, at least in some population subgroups. Studies using blood vitamin D metabolites to assess vitamin D status may be less prone to misclassification than those of diet and sunlight exposure. Overall, the two prospective and four case-control studies of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D tend to support a protective effect in older women. The relationship between common vitamin D receptor polymorphisms and risk remains unclear. Many questions about this relationship clearly remain, including the utility of assessing vitamin D through diet and sunlight exposure, the relationship between plasma metabolites, and the potential modifying effects of age, menopausal status and tumor characteristics. Given that vitamin D status is modifiable, additional prospective studies are necessary to determine if vitamin D may have important potential for breast cancer prevention.
Vitamin D may suppress infections which lead to development of Multiple Sclerosis
Steven R Brenner, None (16 August 2007)
J Neurol Neurosurg Psychiatry 2008
I read the article with reference to the inverse relationship between multiple sclerosis clinical activity and deficiency of vitamin D by Soilu-Hannienen (1) with interest, and was considering what mechanism could be in play to cause such a relationship.
25-hydroxylated metabolites of vitamin D act as intracellular regulators of the synthesis and action of defensin (2) molecules against bacterial antigens, defensin being an endogenously synthesized antimicrobial substance (2).
Human cathelicidin antimicrobial peptide gene is a target of vitamin D receptor and is strongly up-regulated by 1,25-dihydroxyvitamin D3, indicating vitamin D receptor and the 1,25-dihydroxyvitaminD3 regulate primate innate immunity (3)
Relationships especially the long term ones need constant love and attention. Sexual intimacy is the wonderful expression of love and no one can ever deny this. But there are couples which are unable to enjoy sex due to erectile dysfunction and that are what most frustrating for them.
Now you might be thinking what is the key to a successful love relationship? Many experts say that relationships work on the foundation of trust, love, respect, honesty and patienc
Vitamin D status and its relationship to body fat, final height, and peak bone mass in young women.\nKremer R, Campbell PP, Reinhardt T, Gilsanz V.\nJ Clin Endocrinol Metab. 2009 Jan;94(1):67-73. Epub 2008 Nov 4.\nPMID: 18984659
Xu YC, Leung SW, Yeung DK, Hu LH, Chen GH, Che CM, Man RY.
Structure-activity relationships of flavonoids for vascular relaxation in porcine coronary artery.
Phytochemistry. 2007 Mar 27; [Epub ahead of print]
PMID: 17395220 [PubMed - as supplied by pu
Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D.
Vieth R, Ladak Y, Walfish PG.
J Clin Endocrinol Metab. 2003 Jan;88(1):185-91.
PMID: 12519850
This study shows that all age groups exhibit a high prevalence of 25(OH)D insufficiency and secondary hyperparathyroidism. Older adults are just as efficient in maintaining 25(OH)D, but they need more vitamin D to produce the higher 25(OH)D concentrations required to overcome the hyperparathyroidism associated with their diminishing renal function
The relationship between the fatty acid composition of immune cells and their function.
Calder PC.
Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):101-8. Epub 2008 Oct 23. Review.
PMID: 18951005
doi:10.1016/j.plefa.2008.09.016
An inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individuals
M A Micallef, I A Munro and M L Garg
Eur J Clin Nutr 63: 1154-1156; advance online publication, April 8, 2009; doi:10.1038/ejcn.2009.20
Relationship between the in vitro response of dendritic cells to Lactobacillus and prevention of tumorigenesis in the mouse.
Takagi A, Ikemura H, Matsuzaki T, Sato M, Nomoto K, Morotomi M, Yokokura T.
J Gastroenterol. 2008;43(9):661-9. Epub 2008 Sep 20.
PMID: 18807127
DOI: 10.1007/s00535-008-2212-7
Relationships between 25-Hydroxyvitamin D Levels and Plasma Glucose and Lipid Levels in Pediatric Outpatients.
Johnson MD, Nader NS, Weaver AL, Singh R, Kumar S.
J Pediatr. 2009 Nov 17. [Epub ahead of print]
PMID: 19926097
Conclusions
Low 25(OH) D levels in children and adolescents are associated with higher plasma glucose and lower HDL concentrations.
Relationship between low ultraviolet B irradiance and higher breast cancer risk in 107 countries.
Mohr SB, Garland CF, Gorham ED, Grant WB, Garland FC.
Breast J. 2008 May-Jun;14(3):255-60. Epub 2008 Apr 17.
PMID: 18422861
DOI: 10.1111/j.1524-4741.2008.00571.x
There was a protective effect of UVB irradiance on risk of breast cancer that was independent of fertility rate, proportion of the population overweight, alcohol intake, animal energy intake, and other covariates.
Relationship of dietary linoleic acid to blood pressure. The International Study of Macro-Micronutrients and Blood Pressure Study [corrected]
Miura K, Stamler J, Nakagawa H, Elliott P, Ueshima H, Chan Q, Brown IJ, Tzoulaki I, Saitoh S, Dyer AR, Daviglus ML, Kesteloot H, Okayama A, Curb JD, Rodriguez BL, Elmer PJ, Steffen LM, Robertson C, Zhao L; International Study of Macro-Micronutrients and Blood Pressure Research Group.
Hypertension. 2008 Aug;52(2):408-14. Epub 2008 Jul 7. Erratum in: Hypertension. 2008 Sep;52(3):e29.
PMID: 18606902
doi: 10.1161/HYPERTENSIONAHA.108.112383
Dietary linoleic acid intake may contribute to prevention and control of adverse blood pressure levels in general populations
Triguna Yoga Rishikesh offers 200 Hours and 300 Hours of Yoga Teacher Training, Meditation Teacher Training, Meditation, Body Purification Retreat in India. We basically rotate around the relationship among frontal cortex and body through yoga asana, reflection, and breathing philosophies.
Triguna Yoga Rishikesh offers 200 Hours and 300 Hours of Yoga Teacher Training, Meditation Teacher Training, Meditation, Body Purification Retreat in India. We basically rotate around the relationship among frontal cortex and body through yoga asana, reflection, and breathing philosophies.
The healthcare technology industry is no different from other industries in having fashion and trends. Two years ago, PHR (Personal Health Records) systems were fashionable and today they're not - probably because the business model for PHR applications is unclear and unproven. Today - social networking for healthcare is hot and I'm confident that once the market shakes out the buzz words from the business, we'll see social software playing a big part in revolutionizing healthcare with vastly more effective doctor-patient communications and collaboration, improved outcomes, better compliance and better patient education.
A recent German study showed that drinking water before meals helps reduce weight, this study has been published in "American Journal of Clinical Nutrition," and showed that the middle-age and older who drink 2 glasses of water before each meal lost 2 pounds in period of study, compared to those who did not drink as another study showed the existence of a strong relationship between drinking a liter of water and weight loss.
Researchers over the last few years know that there is a positive
relationship between components in food and between foods that
work together for maximum health benefits.
There are all types of food synergy, from different nutrients that are
found together in the same whole food, to nutrients in different foods
that work better together, to the synergy in certain dietary patterns.
Read the full article to know all about the "power couples".