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Matti Narkia

Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabe... - 0 views

    Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans.
    Pani MA, Knapp M, Donner H, Braun J, Baur MP, Usadel KH, Badenhoop K.
    Diabetes. 2000 Mar;49(3):504-7.
    PubMed PMID: 10868975.
    doi: 10.2337/diabetes.49.3.504
Matti Narkia

200 Free Online Classes to Learn Anything | OEDb - 0 views

    A high quality education doesn't have to come at a high cost. In fact, it's possible to take classes from big names like Yale, MIT, and Tufts without ever submitting an application or paying a cent in tuition. We've compiled 200 online classes from these and other respected institutions, and you can take all of them with no strings attached.
Matti Narkia

The importance of selenium to human health. [Lancet. 2000] - PubMed Result - 0 views

    The importance of selenium to human health.
    Rayman MP.
    Lancet. 2000 Jul 15;356(9225):233-41. Review.
    PMID: 10963212
Matti Narkia

Combination Immunotherapy of Squamous Cell Carcinoma of the Head and Neck: A Phase 2 Tr... - 0 views

    Combination immunotherapy of squamous cell carcinoma of the head and neck: a phase 2 trial.
    Barrera JL, Verastegui E, Meneses A, Zinser J, de la Garza J, Hadden JW.
    Arch Otolaryngol Head Neck Surg. 2000 Mar;126(3):345-51.
    PMID: 10722007

    The natural cytokine mixture is a collection of natural human cytokines induced from human peripheral blood mononuclear cells. It contains IL-1, IL-2, IL-6, IL-8, IL-10, IL-12, interferon gamma, tumor necrosis factor , and granulocyte-macrophage and granulocyte colony-stimulating factor in nanogram quantities. It lacks IL-3, IL-4, IL-5, and IL-7.


    This IRX-2 strategy uses perilymphatic local administration along with contrasuppression with low-dose cyclophosphamide and indomethacin and with zinc replacement therapy (as an immunorestorative). The data presented herein demonstrate that H&N SCC can respond very well to immunotherapy: there was a response rate of 100% in this series of 15 patients, with clinical reduction in tumor (1 complete response, 7 partial responses, and 7 minor responses) and histological evidence of tumor regression of 42%. Overall, the average combined estimated tumor reduction exceeded 70%. Also, patients with oral cancer noted marked analgesic and hemostatic effects from this therapy, with healing of oral lesions.


    It is important to note that adjuvant chemotherapy is not used at INCAN. Many studies23 indicate that treatment with fluorouracil and cisplatin, the combination most in use, is effective for reducing tumors in the majority of patients; however, with no meaningful impact on survival, their routine use in the United States has recently been questioned.24-25 The expense, toxic effects, and lack of effectiveness of both drugs has made their use in other less affluent countries unwarranted. The current data on the use of IRX-2 in this and other protocols8-10 hint at improved survival, and a phase 3 randomized controlled study comparing this protocol with chemotherapy arm is to be initiat
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