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No surprise that Testosterone therapy improves Testosterone levels in men with low T, but aromatase inhibition (AI) did as well.  In this study, only lean mass increased compared to Testosterone therapy and placebo.  Strength increased in both Testosterone and AI.

recent study proves the scientific validity of sex hormone evaluation via saliva.  Most labs today use ELIZA.  The new future will be mass spectroscopy.

salivary testosterone, as measured by LC-MS and ELISA, showed strong correlation with serum free "calculated" testosterone.

If time is of the essence and weight loss is your greatest concern, cardio is your best approach.  Resistance training would be the least best approach.  Obviously, this should be customized.

this study looked at salivary testosterone to serum testosterone and found poor correlation.  One major problem with this study is the significantly smaller amount (10 fold) of testosterone in women than men in healthy individuals.  This study took place in postmenopausal women, which would have significantly lower levels than healthy women.  They also don't discuss the pitfalls of equilibrium dialysis of serum free testosterone.  Another major flaw is the mere logic of looking at serum for tissue activity.   What is the correlation between serum levels and tissue activity.  There is tremendous assumptions being undertaken that serum levels of testosterone whether total or free translate to genomic or non-genomic signaling.  I also wonder if newer techniques using Mass Spec can better detect the typically pico levels of testosterone in women's saliva?  This study does nothing to dissuade the use of salivary testing.

Only abstract available: resistance training in first half of female cycle found to increase muscle mass and strength beyond that of the last 2 weeks.  No difference was found in the use of OCPs.

Increased fat mass equals increased aromatase estrogen production and low T.

Meta-analysis finds that Testosterone therapy in men 40+ reduced total body fat with an increase in fat free mass. 

this study of 40 obese patients found saliva cortisol testing less specific than urinary; but more than Dexamethasone suppression test.  The problem with this is several fold: first, this is done via ELIZA and not Mass Spec and second, 24 hour urine collection is hard to achieve in real life.

type and length of training effects testosterone secretion. Testosterone plays an important role in muscle performance and mass. Prolonged training can result in a decrease in testosterone level. This has significance with highly trained athletes. One pitfall of this study was the assessment of testosterone via serum.

European Journal of Endocrinology finds that salivary cortisol can be used as a diagnostic tool for Cushing's syndrome and adrenal insufficiency.  Thus both hypercortisol and hypocortisol states can be followed using saliva.  This statement was using immunoassay.  Mass spectroscopy provides even better results

MS-LS show to be highly sensitive in the dual identification of testosterone and cortisol in saliva. These hormones were found to be stable up to 28 days at room temperature. This disproves the argument that saliva, as a test medium, has a very short shelf life.

LC-MS/MS shown to be reliable in salivary cortisol evaluation.  Obese individuals create special challenges with regards to coritsol levels, due to peripheral cortisol to cortisone conversion.   This study points out that saliva should not be used solely in the diagnosis of Cushing's syndrome due to unreferenced norms.   That however, doesn't nullify salivary cortisol.  It requires a look at the references.  for those that are obese and being evaluated for cushing's.  There is no perfect test.  T This study is a little misleading in its conclusion.  Salivary testing is valid, but the reference ranges in the obese with suspected cushing's syndrome needs further evaluation: according to these authors.

Opinion aside, a study of the individual mandate in MASS, shows that hospital productivity dropped.  And that is in the face of already poor productivity.

This study looked at combined sex hormone analysis via gas chromatography-mass spec.  Levels were able to be detected as low as 0.002 mcro/L in saliva.  This study validates the GC-MS for the use of multiple, simultaneous steroid hormone analysis

LC-MS for salivary testosterone and DHEA validated.  Also, T and DHEA were shown to have specific diurnal rhythms.  Changes in levels were also followed after DHEA therapy.

Testosterone increases muscle mass, strength and cell number.

Testosterone therapy slows visceral fat accumulation and increases muscle mass.

Testosterone therapy is complex in hypogonadism.  Much of the marketing-based medicine of Low T today is in fact doping.  Increasing weight is clearly associated with a declining T level in men.  Testosterone therapy should be approach individually and therapies that use the one size fits all approach never work.  This is the case whether the use of synthetics or natural hormones are employed.  Testosterone has been shown to improve dysglycemia, MetS, reduce fat and increase muscle mass.  

Article discusses the expanding evidence of low T and Metabolic syndrome.