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Nathan Goodyear

Pituitary Function in a Man with Congenital Aromatase Deficiency: Effect of Different Doses of Transdermal E2 on Basal and Stimulated Pituitary Hormones -- Rochira et al. 87 (6): 2857 -- Journal of Clinical Endocrinology & Metabolism - 0 views

  • the congenital lack of estrogen activity seems to be associated with a slightly impaired secretion of PRL and TSH
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    low estrogen in men inhibits TSH 
Nathan Goodyear

Controversial issues of dietary fat and experiment... [Prev Med. 1993] - PubMed result - 0 views

  • A voluminous amount of information is also available in the literature linking increased fat consumption, particularly polyunsaturated fat, and stimulation of mammary tumorigenesis
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    diet high omega-6 increases breast cancer metastasis
Nathan Goodyear

Association between Blood Pressure and Serum Thyroid-Stimulating Hormone Concentration within the Reference Range: A Population-Based Study -- Åsvold et al. 92 (3): 841 -- Journal of Clinical Endocrinology & Metabolism - 0 views

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    subclinical hypothyroidism associated with elevated B/P and cardiovascular disease
Nathan Goodyear

Does Cimetidine Improve Prospects for Cancer Patients? - 0 views

  • Most studies suggest that cimetidine may improve the outcome in cancer patients by a three-pronged mechanism involving (1) inhibition of cancer cell proliferation; (2) stimulation of the lymphocyte activity by inhibition of T cell suppressor function, and (3) inhibition of histamine’s activity as a growth factor in tumours.
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    cimetidine as therapy for cancer?  Yes, read review
Nathan Goodyear

Effect of sodium fluoride on tumor growth - 0 views

  • The data appear to establish the association of NaF with acceleration of the growth of tumor
  • It has been reported (1) that NaBr likewise has a stimulating effect on tumor growth
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    flourine increases tumor cell growth; supports the observation that cancer deaths are higher in cities with flouridated water
Nathan Goodyear

Coenzyme Q10 reverses pathological phenotype and r... [Neurology. 2001] - PubMed result - 0 views

  • The authors conclude that muscle CoQ10 deficiency can be corrected by supplementation of CoQ10, which appears to stimulate mitochondrial proliferation and to prevent apoptosis.
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    CoQ10 supplementation shown to resolve familial CoQ10 deficiency
Nathan Goodyear

A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly - 0 views

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    amino acid leucine promotes muscle protein synthesis
Nathan Goodyear

TSH is a poor measure of severity of tissue hypothyroidism - 0 views

  • Thyroid stimulating hormone (TSH) tests are not useful for estimating the clinical and metabolic severity of primary overt thyroid failure. Meier and colleagues (p311) found that, in contrast with the accuracy of serum TSH measurement in the early diagnosis of hypothyroidism, clinical markers and circulating thyroid hormones much more accurately reflect the degree of tissue hypothyroidism. Initiation of replacement therapy should be guided by clinical presentation and circulating thyroid hormones and not by TSH concentrations
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    TSH is not a useful test
Nathan Goodyear

Leptin serves body as energy signal | Harvard Gazette - 0 views

  • replacing leptin to physiologically normal levels during fasting fully restored testosterone to baseline, indicating that leptin regulates the hypothalamic-pituitary- gonadal axis that controls the release of testosterone and estrogen
  • Leptin clearly has some effect on the thyroid hormone axis,
  • including thyroid-stimulating hormone and the free-circulating form of thyroid
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    Leptin regulates hypothalamic-pituitary axis; and don't forget thyroid too.
Nathan Goodyear

Kent Holtorf: Long Term Weight Loss - More Than Will Power? - 0 views

  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • f greater than 10, it demonstrates there is a degree of leptin resistance contributing to an inability to lose weight
  • that it is difficult to lose weight with leptin resistance. High carbohydrate diets and in particular high-fructose corn syrup is shown to significantly increase leptin resistance and is a likely mechanism that high fructose corn syrup is associated with obesity
  • ...9 more annotations...
  • inactive thyroid hormone called thyroxine
  • it is problem inside the cell that the inactive T4 is not converted to T3 but rather to a mirror image of T3 called reverse T3. The reverse T3 has the opposite effect of T3, blocking the effects of T3 and lowering rather than increasing metabolism.
  • Studies are showing that stress and dieting (especially yo-yo dieting) can set this hormone into action as well as chronic illness such as diabetes, chronic fatigue syndrome and fibromyalgia.
  • As soon as the body senses a reduction in calories, the production of reverse T3 is stimulated to lower metabolism
  • With chronic dieting or stress, the body often stays in this "starvation mode" with elevated levels of reverse T3 and decreased levels of T3, which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • Studies are showing that such standard testing will miss 80% of thyroid dysfunction
  • ree T3/reverse T3 ratio
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    Fantastic review by Dr. Holtorf on reverse T3, leptin, and weight loss
Nathan Goodyear

1alpha,25-dihydroxyvitamin D3 interacts with curcu... [J Alzheimers Dis. 2009] - PubMed result - 0 views

  • 1,25D3 strongly stimulated Abeta phagocytosis and clearance while protecting against apoptosis
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    Vitamin D3 and Alzheimer's disease
Nathan Goodyear

Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial - 0 views

  • Omega-3 fatty acids stimulate muscle protein synthesis in older adults
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    Omega-3 shown to increase muscle growth
Nathan Goodyear

Effect of Cs-4® (Cordyceps sinensis) on Exercise Performance in Healthy Older Subjects: A Double-Blind, Placebo-Controlled Trial - The Journal of Alternative and Complementary Medicine - 0 views

  • the metabolic threshold (above which lactate accumulates) increased by 10.5%
  • he ventilatory threshold (above which unbuffered H+ stimulates ventilation) increased by 8.5%
  • upplementation with Cs-4 (Cordyceps sinensis) improves exercise performance and might contribute to wellness in healthy older subjects
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    cordyceps sinensis and lactate
Sonny Cher

Relive the Spicy Moments - 1 views

My sex life has been dull and boring lately. I do not feel the thrill and excitement as before. I was looking for ways to fix it before it is too late, then I found out about Librex legal drugs and...

legal drugs high

started by Sonny Cher on 08 Jun 11 no follow-up yet
Sonny Cher

Relive the Spicy Moments - 1 views

My sex life has been dull and boring lately. I do not feel the thrill and excitement as before. I was looking for ways to fix it before it is too late, then I found out about Librex legal drugs and...

legal drugs high

started by Sonny Cher on 08 Jun 11 no follow-up yet
Nathan Goodyear

Inositolphosphoglycans (IPGs) as mediators of insu... [J Basic Clin Physiol Pharmacol. 1998] - PubMed result - 0 views

  • There is substantial evidence to suggest that some IPGs may also be responsible in part for mediating insulin's stimulation of glucose disposal
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    Inositolphosphoglycans function as intermediate in insulin/glucose regulation
Nathan Goodyear

Guidelines have done more harm than good. [Blood Purif. 2008] - PubMed result - 0 views

  • Guidelines certainly do not encourage clinicians to consider and treat each patient as an individual
  • This all but guarantees many guidelines are obsolete by the time they are published
  • unlikely to stimulate original research
  • ...2 more annotations...
  • reated by a process that is artificial, laborious and cumbersome
  • uidelines are produced with industry support and recommendations often have a major impact on sales of industry products
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    Medical guidelines likely do more harm than good
Nathan Goodyear

Dietary Sugars Stimulate Fatty Acid Synthesis in Adults - 0 views

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    fructose intake equals fat storage
Nathan Goodyear

Anemia in patients on combined androgen block therapy for prostate cancer - 0 views

  • testosterone and 5b-dihydrotestosterone stimulate erythropoietin production in laboratory animals [2]. Before the discovery of recombinant erythropoietin, androgens were used clinically to improve haematocrit levels in anaemic patients
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    Testosterone and DHT increase hematocrit in men with anemia
Nathan Goodyear

-Absence of Melatonin and Insulin Resistance - 0 views

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    insulin resistance associated with absence of melatonin
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