Skip to main content

Home/ Dr. Goodyear/ Group items tagged anemia

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Anemia in cancer - 0 views

annonc.oxfordjournals.org/...vii167.long

cancer anemia

shared by Nathan Goodyear on 30 Mar 15 - No Cached
  • Anemia is a frequent finding in cancer patients, occurring in >40% of cases
  • chemotherapy, the incidence of anemia may rise to 90%
  • Anemia exerts a negative influence on the quality of life
  • ...17 more annotations...
  • Anemia has also been identified as an adverse prognostic factor
  • mild (10 g/dl—normal), moderate (8–10 g/dl), severe (6.5–8 g/dl) and life threatening (<6.5 g/dl or unstable patient) anemia
  • anemia in cancer patients is often multifactorial.
  • Cancer itself can directly cause or exacerbate anemia either by suppressing hematopoiesis through bone marrow infiltration or production of cytokines that lead to iron sequestration, or by reduced red blood cell production
  • in inflammatory anemia, iron deficiency should be defined by a low transferrin saturation of <20%, ferritin levels of <100 ng/ml and a low reticulocyte hemoglobin concentration of <32 pg
  • anemia to thrombocytosis, as commonly seen in cancer patients
  • TNF-α inhibits hemoglobin production
  • treatment itself may be a major cause of anemia
  • Other cytokines, such as interleukin-6 (IL-6), IL-1 and interferon-γ, have also been shown to inhibit erythroid precursors in vitro [9], albeit to a lesser extent
  • In inflammation, from whatever cause, IL-6 induces the liver to produce hepcidin. Hepcidin decreases iron absorption from the bowel and blocks iron utilization in the bone marrow
  • Numerous in vitro studies have illustrated the central role of TNF-α in the pathogenesis of anemia
  • nephrotoxic effects of particular cytotoxic agents such as platinum salts can also lead to the persistence of anemia through reduced Epo production by the kidney
  • Currently two options are at the disposal of the clinician for the treatment of anemia in cancer patients: transfusion of packed red blood cells and the use of erythropoiesis-stimulating agents (ESAs)
  • The goal of the treatment is to relieve the symptoms of anemia such as fatigue and dyspnea.
  • Transfusion of 1 unit of packed red blood cells has been estimated to result in an increase in the hemoglobin level of 1 g/dl in a normal-sized adult
  • a higher mortality rate in patients receiving ESA treatment
  • Recent concerns regarding the risk of thromboembolism in patients treated with ESA have been corroborated by the meta-analyses conducted by Tonnelli and Bennett
  • Nathan Goodyear on 30 Mar 15
     
    Great review of anemia in Cancer:  1)  blood loss 2)  increased RBC loss 3)   decreased RBC production Cancer infiltration of marrow can reduce hematopoiesis.  Inflammatory cytokines can reduce hematopoiesis.  Inflammatory cytokines can block Fe absorption.  Chemo and radiation can cause anemia--particularily platinum based therapies.
Nathan Goodyear

Delayed-Onset Hemolytic Anemia in Patients with Travel-Associated Severe Malaria Treate... - 0 views

wwwnc.cdc.gov/...14-1171_article

artesunate anemia

shared by Nathan Goodyear on 18 Jul 18 - No Cached
  • delayed hemolytic events occur in ≈20% of patients with severe imported malaria, and 60% of these patients require blood transfusion
  • Delayed-onset anemia (herein referred to as postartesunate delayed-onset hemolysis [PADH] pattern of anemia) has been observed to occur 2–3 weeks after initiation of IV artesunate
  • The mechanism of this anemia is hemolytic, as demonstrated by high serum lactate dehydrogenase (LDH) and low plasma haptoglobin levels
  • ...5 more annotations...
  • this side effect is associated with artesunate
  • PADH occurred in 27% of patients in this study, but it was rarely associated with severe anemia and was never fatal
  • median delayed drop in hemoglobin levels was 1.3 g/dL
  • This transfusion rate (<5%) is markedly lower than that previously reported for patients with severe imported malaria and delayed-onset anemia (≈60%)
  • Side effects of artesunate frequently include gastrointestinal disturbances, neutropenia (1.3%), reticulocytopenia (0.6%), and elevated liver enzymes (1.1%)
  • Nathan Goodyear on 18 Jul 18
     
    artesunate
Nathan Goodyear

Anemia, testosterone, and pituitary adenoma in men; Journal of Neurosurgery - 98(5):Pag... - 0 views

thejns.org/...jns.2003.98.5.0974

anemia low testosterone T hematopoiesis

shared by Nathan Goodyear on 01 Sep 11 - No Cached
  • Nathan Goodyear on 01 Sep 11
     
    low Testosterone equals anemia in men.  Low T will result in reduced hematopoiesis and thus resultant anemia
Nathan Goodyear

Access : Intravenous vitamin C can improve anemia in erythropoietin-hyporesponsive hemo... - 0 views

www.nature.com/...ncpneph0281.html

IV vitamin C vitamin C vitamin C IV intravenous vitamin C anemia

shared by Nathan Goodyear on 26 Aug 14 - No Cached
  • Nathan Goodyear on 26 Aug 14
     
    IV vitamin C improves anemia.  The only possible contribution of IV vitamin C and anemia is a G6PD deficiency.
star yu

Cómo Tratar la Anemia en la Enfermedad Renal Crónica - 0 views

www.enfermedad-renal.com/...2590.html

las medicinas hierbas

shared by star yu on 18 Oct 15 - No Cached
  • star yu on 18 Oct 15
     
    A menudo ,la anemia no puede ocurrir hasta el paciente ha entrado la etapa 3 de la enfermedad renal , mientras que en algunos casos para provocar la anemia ocurre tan temprano. ¿Por qué vincular estrechamente con la anemia de enfermedad renal crónica?¿Hay un tratamiento para tratar la anemia con enfermedad renal cronica?El siguiente contenido explicará en detalle.
Nathan Goodyear

Anaemia in men receiving combined finasteride and fl... [BJU Int. 1999] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10233450

anemia testosterone DHT prostate cancer finasteride flutamide

shared by Nathan Goodyear on 02 Sep 11 - No Cached
  • Nathan Goodyear on 02 Sep 11
     
    anti-testosterone therapy with finasteride and flutamide in prostate cancer leads to anemia, proving that testosterone and DHT protect against anemia.
Nathan Goodyear

Anemia as an independent prognostic factor for survival in patients with cancer - Caro ... - 0 views

onlinelibrary.wiley.com/...full

anemia cancer

shared by Nathan Goodyear on 30 Mar 15 - No Cached
  • Anemia is common in cancer patients,1, 20 and it has been associated with lower survival
  • median survival was reduced by 20–43%
  • Nathan Goodyear on 30 Mar 15
     
    anemia is a poor prognostic biomarker in cancer.  But is it simply a biomarker of more advanced disease and thus merely the result of poor health?
fnfdoc

Symptoms Of Aplastic Anemia | Your Health Our Priority - 0 views

www.fnfdoc.com/...symptoms-aplastic-anemia

Acquired Aplastic Anemia Inherited

shared by fnfdoc on 09 May 18 - No Cached
  • fnfdoc on 09 May 18
     
    Aplastic Anemia is a rare but serious disease of the blood cells. It is diagnosed by the inability of the bone marrow to synthesize RBCs, WBCs and platelets. The spongy bone marrow contains stem cells that are actively involved in Hematopoiesis.
star yu

Cómo Tratar la Anemia en la Insuficiencia Renal - 0 views

www.hospitalrenal.com/...780.html

anemia

shared by star yu on 27 Jun 15 - No Cached
  • star yu on 27 Jun 15
     
    Cómo tratar la anemia en la insuficiencia renal?La insuficiencia renal paciente experimentará muchos tipos de síntomas y complicaciones, la anemia es uno de ellos, que hará que la gente débil y cansado.Así que el tratamiento de la misma se concernd con muchos pacientes con enfermedad renal.
Nathan Goodyear

Anemia in patients on combined androgen block therapy for prostate cancer - 0 views

www.asiaandro.com/...383.htm

testosterone DHT anemia men hematocrit androgens

shared by Nathan Goodyear on 02 Sep 11 - No Cached
  • testosterone and 5b-dihydrotestosterone stimulate erythropoietin production in laboratory animals [2]. Before the discovery of recombinant erythropoietin, androgens were used clinically to improve haematocrit levels in anaemic patients
  • Nathan Goodyear on 02 Sep 11
     
    Testosterone and DHT increase hematocrit in men with anemia
Nathan Goodyear

Arch Intern Med -- Low Testosterone Levels and the Risk of Anemia in Older Men and Wome... - 0 views

archinte.ama-assn.org/...1380

low testosterone levels anemia men

shared by Nathan Goodyear on 01 Sep 11 - No Cached
  • Nathan Goodyear on 01 Sep 11
     
    Low Testosterone is a cause of anemia in men
star yu

Cómo aliviar la anemia en la enfermedad renal poliquística (PKD) - 0 views

www.enfermedad-renal.com/...2074.html

enfermedad renal poliquística tratamiento

shared by star yu on 10 Mar 15 - No Cached
  • star yu on 10 Mar 15
     
    La anemia es el síntoma común y más temprana de la enfermedad renal poliquística, los pacientes con anemia puede sufrir los síntomas como debilidad, fatiga y la cara pálida etc.Si no se trata, se aceleró la progresión a la insuficiencia renal.Por lo tanto, es necesario para tratar la anemia por adelantado. Entonces,qué puede hacer PKD pacientes para aliviar la complicación.
Nathan Goodyear

Management of cancer-associated anemia with erythropoiesis-stimulating agents: ASCO/ASH... - 0 views

www.ncbi.nlm.nih.gov/...PMC6482353

cancer anemia

shared by Nathan Goodyear on 08 Jun 19 - No Cached
  • Nathan Goodyear on 08 Jun 19
     
    New "guidelines" for management of anemia in cancer.
Nathan Goodyear

Vitamin C and functional iron deficiency anemia in hemodialysis - 0 views

www.ncbi.nlm.nih.gov/...PMC4715087

Iron anemia vitamin C Hepcidin

shared by Nathan Goodyear on 09 May 20 - No Cached
  • Nathan Goodyear on 09 May 20
     
    Proposed that IV vitamin C reduces Hepcidin induced anemia.
Nathan Goodyear

Erythropoietin, GDF15, IL6, hepcidin and test... [Eur J Haematol. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21535154

low T testosterone men anemia

shared by Nathan Goodyear on 02 Sep 11 - No Cached
  • Nathan Goodyear on 02 Sep 11
     
    anemia of unknown origin associated with low Testosterone in men
Nathan Goodyear

Low testosterone and anaemia in men with type 2 diabetes - Grossmann - 2008 - Clinical ... - 0 views

onlinelibrary.wiley.com/...full

low testosterone T anemia men male

shared by Nathan Goodyear on 01 Sep 11 - No Cached
  • Nathan Goodyear on 01 Sep 11
     
    low Testosterone contributes to anemia in men
Nathan Goodyear

Andropause. Testosterone replacement therapy for aging men. - 0 views

www.cfp.ca/91.short

low T Testosterone anemia men male aging

shared by Nathan Goodyear on 01 Sep 11 - No Cached
  • Nathan Goodyear on 01 Sep 11
     
    always think low Testosterone with men with anemia
Nathan Goodyear

The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix - G... - 0 views

onlinelibrary.wiley.com/...full

anemia cancer

shared by Nathan Goodyear on 30 Mar 15 - No Cached
  • Nathan Goodyear on 30 Mar 15
     
    Prognosis in cancer is reduced with anemia.  This study found a resolution with transfusion.
Nathan Goodyear

The relationship of pretreatment serum hemoglobin level to the survival of epithelial o... - 0 views

onlinelibrary.wiley.com/...full

anemia cancer

shared by Nathan Goodyear on 30 Mar 15 - No Cached
  • Nathan Goodyear on 30 Mar 15
     
    anemia associated with aggressive cancer and thus poor prognosis.
Nathan Goodyear

Megaloblastic Anemia and Other Causes of Macrocytosis - 0 views

www.ncbi.nlm.nih.gov/...PMC1570488

macrocytosis MCV anemia

shared by Nathan Goodyear on 22 Sep 14 - No Cached
  • Nathan Goodyear on 22 Sep 14
     
    macrocystosis
1 - 20 of 39 Next ›
Showing 20▼ items per page