Cytotoxic Effects of Klebsiella oxytoca Strains Isolated from Patients with Antibiotic-... - 0 views
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Nathan Goodyear on 14 Apr 14Colitis as a result of K. oxytoca
Nathan Goodyear
Contents contributed and discussions participated by Nathan Goodyear
Neonatal abstinence syndrome and associated health care... [JAMA. 2012] - PubMed - NCBI - 0 views
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Very disturbing trend. Study finds that opioid addicted infants are on a dramatic risk in the US. This study looked at Neionatal abstinence syndrome from 2000 to 2009. This follows the significant increase in maternal opioid prescription use. We physicians must do better. Patients must demand better. This study just focused on hospital costs directly associated with the Neonatal period. No cost estimates are evaluated for long-term care.
Association between sex hormone-binding glob... [Sao Paulo Med J. 2014] - PubMed - NCBI - 0 views
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low levels of SHBG associated with increasing incidence of metabolic syndrome in men ages 40-70.
Effect of different seasonal strength trai... [Hormones (Athens). 2014] - PubMed - NCBI - 0 views
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Increased strength training associated with increased Total Testosterone and 3-alpha androstane idol levels in trained athletes. This was not found in free Testosterone levels.
Access : Prognostic and predictive value of plasma testosterone levels in patients rece... - 0 views
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Higher base-line Testosterone levels associated with longer overall survival in men with prostate cancer. The comparison was 32.7 months with higher T levels versus 22.4 months with lower T levels. Anemia was also a poor prognostic variable. Whether exogenous Testosterone therapy will change this is still unclear, but the authors suggest that this should play a role in whether to use salvage hormone therapy.
High-dose vitamin D supplementation and measur... [Fertil Steril. 2014] - PubMed - NCBI - 0 views
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No significant statistical significance was found with vitamin D therapy and insulin sensitivity. However, improved outcomes were found in 2 hour insulin and 2 hour glucose levels after a 75 gram OGTT.
Access : Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a... - 0 views
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Meta-analysis finds that low vitamin D is more associated with mortality in women with breast cancer than increased incidence.
Testosterone, aging and s... [Curr Opin Endocrinol Diabetes Obes. 2014] - PubMed - NCBI - 0 views
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Another review study. Low Testosterone is associated with increased CVD in men. However, some studies have suggested an increase in CVD with men using exogenous Testosterone therapy. Is Testosterone the cause of CVD in men? Likely, low T is a
Testosterone and cardiova... [Curr Opin Endocrinol Diabetes Obes. 2014] - PubMed - NCBI - 0 views
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Review of recent articles suggest increased risk of cardiovascular disease in men. The issue at hand is the cause is not being treated and thus the Testosterone is fuel on the metabolic fire and the doping dose that most men receive.
JAMA Network | JAMA Internal Medicine | Sildenafil Use and Increased Risk of ... - 0 views
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Viagra associated with a 84% increased risk of melanoma. The key word here is associated. No cause and effect relationship is seen. Anytime use was also associated with increased risk. This study did not look at the other phopsphodiesterase 5 inhibitors, though the logic is there risk may be higher as they are longer acting.
Testosterone therapy affects Mexican American men differently - UNT Health Science Cent... - 0 views
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This is the public announcement of a article yet to be published. The study, yet unread, points to increase damage to brain health in those caucasian men with oxidative stress. This was not found in mexican-Americans. Until I read this study, that is all I will say here.
http://eurheartj.oxfordjournals.org/content/34/48/3691.full.pdf#page=1&view=FitH - 0 views
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A large body of evidence exists to associate low vitamin D with cardiovascular disease. However, this review finds no causal relationship. Is vitamin D an indicator of poor health? Or is it the cause of poor health. Yet to be determined. Is vitamin D safe? Yes.
http://www.update-software.com/BCP/WileyPDF/EN/CD007365.pdf - 0 views
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meta-analysis found no high level of evidence to support Huperzine A in the treatment of vascular dementia. The conclusion sounds scientifically sound, but when you look at the studies included: this is a meta-analysis of 1 of Huperzine A and vascular dementia. This one study was of 14 participants only and they found improvement in daily functioning. There are a lot of animal studies that point out benefits of huperzine A and even the mechanisms of action, but human studies are lacking. That is a better conclusion.
Ginsenoside Rg3 Alleviates Lipopolysaccharide-Induced Learning and Memory Impairments b... - 0 views
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Rat model induced inflammatory reaction in brain via LPS injection. The result was impaired memory. RG3 from panax ginseng was shown to reduce inflammation, TNF-alpha, IL-1beta, cox-2, thus improving memory and cognitive function.
Treating senile dementia with traditional Chinese medicine - 0 views
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Great review of the literature supporting herbal therapies in the treatment of dementia.
The inhibitory effects of garlic and Panax ginseng extract standardized with ginsenosid... - 0 views
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interesting rat study. EDTA, common chelation therapy of choice for lead (Pb), decreased antioxidant activity and increase lipid per oxidation. This was inhibited by garlic and RG3.
Protective role of Panax ginseng extract standardized with ginsenoside Rg3 against acry... - 0 views
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RG3, an extract from panax ginseng, found to protect against the neurotoxin acrylamide. Also of interest, is that serotonin, corticosterone, T3, T4, estradiol, progesterone and epinephrine were all decreased in this acrylamide rat model.
Huperzine A promotes hippocampal neurogenesis in vitro and in vivo - 0 views
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Huperzine A increases hippocampal neural stem cell proliferation--neurogenesis. This study an animal study.
Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression o... - 0 views
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Huperzine A reduces EAE, an experimental MS model. Thus, huperzine A has a anti-inflammatory effect in the brain.
Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treat... - 0 views
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Huperzine reduces CNS iron. This is in addition to the other neuroprotective effects of Huperzine A
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