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Nathan Goodyear

ScienceDirect - Journal of Steroid Biochemistry : The measurement of hormones in saliva... - 0 views

  • The measurement of the salivary level is a valuable clinical tool for some hormones (e.g. Cortisol, oestriol, progesterone
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    hormone testing in saliva
Nathan Goodyear

Dexamethasone in resting and exercising men. II. Effects on adrenocortical hormones - J... - 0 views

  • The consistent results obtained from the two matrices allow us to consider salivary assays as a useful tool for steroid abuse detection.
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    saliva testing for cortisol, DHEA, androstenedione
Nathan Goodyear

TESTOSTERONE AND Δ4-ANDROSTENEDIONE IN THE SALIVA OF PATIENTS WITH KLINEFELTE... - 0 views

  • measurement of salivary steroids, by reflecting their free hormone concentration in plasma, may be useful in evaluating endocrine function in both health and disease
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    salivary testing of testosterone and androstenedione reflects free hormone concentration in plasma, proving to be very useful in evaluating endocrine function and disease 
Nathan Goodyear

Re: Plasma Sex Steroid Hormone Levels and Risk of Breast Cancer in Postmenopausal Women... - 0 views

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    non-SHBG bound serum estradiol, testosterone and DHEA reveal increase breast cancer risk; other studies show saliva testing equal to serum non-bound SHBG hormones
Nathan Goodyear

Ingestion of androgenic-anabolic steroids induces ... [J Clin Endocrinol Metab. 1993] -... - 0 views

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    Testosterone therapy improves thyroid dysfunction in men
Nathan Goodyear

ScienceDirect - The Journal of Steroid Biochemistry and Molecular Biology : Quercetin a... - 0 views

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    quercetin and resveratrol shown to inhibit estrogen sulfonyltransferase activity.  important implications in estrogen dependent cancers, like breast cancer
Nathan Goodyear

ScienceDirect - The Journal of Steroid Biochemistry and Molecular Biology : Flavonoid i... - 0 views

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    chrysin inhibits aromatase activity in vitro
Nathan Goodyear

Salivary cortisol and DHEA levels in the Korean po... [Yonsei Med J. 2007] - PubMed result - 0 views

  • As the cortisol and DHEA levels in saliva reflected those in serum, the measurement of steroid levels in saliva provide a useful and practical tool to evaluate adrenal functions, which are essential for clinical diagnosis.
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    salivary cortisol and DHEA validated.  
Nathan Goodyear

Correlations between free plasma estradiol and est... [J Steroid Biochem. 1988] - PubMe... - 0 views

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    saliva testing shown to be reliable method of testing for free, acitve, estradiol.
Nathan Goodyear

Effect of training status and exercise mode on endogenous steroid hormones in men - 0 views

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    decreased testosterone production/secretion in men post exercise. This was more pronounced in resistance training versus endurance training.
Nathan Goodyear

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nucl... - 0 views

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    anything and everything you would want to know about NF-kappaB and its dramatic effects on the immune system
Nathan Goodyear

Steroid hormones in multiple sclerosis. [J Neurol Sci. 2005] - PubMed - NCBI - 0 views

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    Pregnancy has a positive effect on MS patients, especially during the 3rd trimester.  Rebound of MS increases in the postpartum period.  Estriol is the dominant pregnancy estrogen.  Progesterone is also produced at high levels.  The withdrawal of these hormones in the postpartum period are likely to lead to this rebound in MS.
Nathan Goodyear

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling: Endocri... - 0 views

  • From a broad perspective, this paradigm can be seen as an example of how hormones are activated or inactivated in a controlled fashion in specific extraglandular tissues, in an analogous role to 5α-reductase and P450 aromatase in sex steroid metabolism and to 11β-hydroxysteroid dehydrogenase in glucocorticoid metabolism.
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    better source for previous post on thyroid metabolism and deiodinase.
Nathan Goodyear

The role of androst-5-ene-3β,17β-diol (androstenedi... [Steroids. 2014] - Pub... - 0 views

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    The DHT metabolite 3beta-androstanediol found to increase proliferation of endometrial tissue in women with PCOS.  In contrast, Testosterone repressed proliferation.  
Nathan Goodyear

Activation of estrogen re... [J Steroid Biochem Mol Biol. 2007 Nov-Dec] - PubMed - NCBI - 0 views

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    It is always important to work out the biochemical mechanism of action.  Study finds Siberian Rhubarbs mechanism of action is through activation ER-beta receptors.  No activity/affinity for ER-alpha found in this study.  This is important as the ER-beta provides an anti-inflammatory, antigrowth signal.
Nathan Goodyear

http://qjmed.oxfordjournals.org/content/early/2014/08/18/qjmed.hcu173.full.pdf#page=1&v... - 0 views

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    Case study published ahead of print--chronic Testosterone use in body building and cardiovascular event in a young man.
Nathan Goodyear

Licorice reduces serum testosterone in heal... [Steroids. 2004 Oct-Nov] - PubMed - NCBI - 0 views

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    Licorice root extract, also known as glycyrrhizic acid, found to quickly reduce endogenous Testosterone production in women.  The proposed mechanism is via inhibition of 17-hydroxysteroid dehydrogenase and 17-20 Lyase.  This is a good adjuvant in the treatment of PCOS.
Nathan Goodyear

Associations between Sex Steroids and the Development of Metabolic Syndrome: a Longitud... - 0 views

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    Men with lower Testosterone levels are associated with increased odds (72%) of Metabolic Syndrome.  This was independent from SHBG and BMI.
Nathan Goodyear

The effect of ezetimibe-statin combination on steroid hormone produ... - PubMed - NCBI - 0 views

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    Statin and combined Ezetimibe-statin therapy reduce Testosterone levels in men--though combination therapy reduced LH and Testosterone levels less than high dose statin therapy, but it still did reduce Testosterone.  This is so counterproductive and reveals much of the thought behind cholesterol.  Low T in men is associated with all CVD.
Nathan Goodyear

Steroid sulfatase gene variation and DHEA r... [Physiol Genomics. 2004] - PubMed - NCBI - 0 views

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    Short 10 week course of resistance exercise associated with an increase in DHEA and DHEAS in both men and women.
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