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Thyroid hormone plays significant role in cardiac remodeling after acute myocardial infarction.  Thyroid hormone, particularly T3 as the vast majority of T3 is produced in heart tissue via D1 enzymatic activity, improves cardiac contractility, reduces systemic vascular resistance, reduces cardiac work load, decreases blood pressure, improves cardiac metabolism, and thus improves outcomes post MI.

Animal model finds that Testosterone improves ventricular remodeling and function following myocardial infarction in male rats.  This similar finding has been found in human studies as well.   Testosterone therapy was found to lower BNP in this rat study.

This is just an abstract due to the publication date.  However, this study, though small, found that elevated estradiol and estrone levels preceded myocardial infarctions in small study group (15).  The surprise was that physical symptoms of slow beard growth, loss of libido, and gynecomastia preceded the events.  Also, the testosterone levels were normal.  Got that: elevated estrogen levels with normal testosterone levels result in significant symptoms.

progesterone shown to provide substantial reduction in volume of infarct in rat stroke model.  This is very promising, and with with other studies revealing the same benefit in the human brain, progesterone should become a part of initial treatment in those with acute brain injuries and should be evaluated for those with aging diseases of the brain.

New cohort study finds increased risk of Testosterone in men > 65 and those : these are based in marketing-based medicine not evidence based medicine.

Low T3 post MI is associated with increased CHF, morbidity and mortality.  Article discusses thyroid hormones and cardiac function/remodeling post infarct.  The article also lays the ground work for a new study of T3 in patients post MI to be followed for 6 months.

reverse T3 predictive of increased mortality in people with myocardial infarctions

homocysteine shown to be a good prognostic marker for patients with prior heart attacks

Calcium can increase MI risk

T3 in the post MI individual decreases the MI infarct size and the progression to heart failure. What is really  interesting about this study is that the T3 induced mitochondrial biogenesis and activity which is a great thing in recovery of MI and also in disease i.e. cancer.  However, it appears to increase HIF-1alpha and angiogenesis which is stimulated by retrograde signaling.  There is a muddied picture here.  Because T3 stimulates oxidative phosphorylation and mitochondria biogenesis which is favorable for health.  However, in this study of rats, it induced HIF-1alpha and angiogenesis in post MI, which is favorable to recovery, yet this is unfavorable for cancer.    Yet oxidative phosphorylation is favorable to cancer prevention/elimination and MI recovery.

Wow, thyroid hormones play a significant role in cardiac remodeling post MI.  Thyroid hormones, "promotes tissue growth and differentiation and favorably remodels cardiac cell while increases cellular survival..."  How many people post-MI are having their thyroid evaluated, let alone correctly evaluated?

androgen deprivation therapy associated with increased type II diabetes, myocardial infarction and CAD.

This study appears to fly in the face of the recent studies on the dangers of Testosterone therapy in those with comorbidities.  This study was a retrospective cohort.  The study found that men in the highest risk for MI, had a reduced MI risk with Testosterone therapy.  Men in the lower risk quartiles had no such benefit.  Of note, the frequency of injections suggests inadequate dosing i.e. 4.4 in first year and 8.2 in follow up.  Most injection regimens will require at least monthly injections, though Testosterone pellets were used.  Of special note, no mention of level testing of Testosterone prior to study and/or during study and follow up.

animal study finds that Testosterone therapy is cardioprotective in a preventative mode and with myocardial injury.  Normalization of Testosterone in these animals with low T reduced infant injury size and improved heart function.  

Retrospective study finds no increase in new MI and/or stroke in men with Testosterone therapy.  There are some men that Testosterone therapy is cardioprotective and some that are not.

Little if any conclusion can be drawn from this study.  There has actually been a call for redaction by experts in the field.

exercise improves survival after heart attack.

Only abstract available here, but EDTA chelation found to reduce risk of death, reinfarction, stroke, hospitalization, angina in individuals with diabetes and prior MI from 38% to 25%.

animal study finds that HBOT reduced stroke infarct size, increased neurogenesis, increased BDNF, and reduced MPO.

Dr. Vipul Gupta India also researches new therapies, such as stem cell therapy for stroke. You can rely on the best interventional neurologist in Delhi India for comprehensive care, from lifesaving stroke and infarct care from you from diagnosis through recovery, ensuring you maintain great neurological health.