Group items tagged hypopituitarism - Dr. Goodyear

Hypopituitarism after traumatic brain injury - 0 views

www.eje-online.org/...679.full

post-traumatic hypopituitarism PTHP TBI traumatic brain injury brain trauma neurology pituitary hypothalamus hormone hormones injury

shared by Nathan Goodyear on 09 Jul 12 - No Cached

PTHP is observed in about 40% of patients with a history of TBI
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Nathan Goodyear on 09 Jul 12

post-traumatic hypopituitarism is found in 40% of those with TBI. The severity does correlate with the increased likelihood of developing PTHP. Isolated deficiencies have been found in PTHP.

<div class="cArrow"> </div><div class="cContentInner">post-traumatic hypopituitarism is found in 40% of those with TBI. The severity does correlate with the increased likelihood of developing PTHP. Isolated deficiencies have been found in PTHP.</div>

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Association between premature mortality and hypopituitarism : The Lancet - 0 views

www.thelancet.com/...fulltext

sex hormone hormones hypopituitarism mortality rate mortality

shared by Nathan Goodyear on 10 Jul 12 - No Cached

Nathan Goodyear on 10 Jul 12

sex hormone treatment in those with hypopituitarism is associated with a significant reduction in mortality.

<div class="cArrow"> </div><div class="cContentInner">sex hormone treatment in those with hypopituitarism is associated with a significant reduction in mortality.</div>

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Hypopituitarism After Multiple Concussions: A Retrospective Case Study in an Adolescent... - 0 views

www.ncbi.nlm.nih.gov/...PMC1978466

concussions concussion head trauma men male hypopituitarism hormone hormones

shared by Nathan Goodyear on 30 Jul 14 - No Cached

Nathan Goodyear on 30 Jul 14

multiple concussions result in hypopituitarism in 14 year old young man.

<div class="cArrow"> </div><div class="cContentInner">multiple concussions result in hypopituitarism in 14 year old young man.</div>

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High Prevalence of Chronic Pituitary and Target-Organ Hormone Abnormalities after Blast... - 0 views

www.ncbi.nlm.nih.gov/...PMC3273706

brain injury TBI traumatic brain injury PTHP post traumatic hypopituitarism low Testosterone T Testosterone hormones

shared by Nathan Goodyear on 20 Jan 16 - No Cached

Nathan Goodyear on 20 Jan 16

The prevalence of post traumatic hypopituitarism post TBI sits at around 35%.

<div class="cArrow"> </div><div class="cContentInner">The prevalence of post traumatic hypopituitarism post TBI sits at around 35%. </div>

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Hypopituitarism after traumatic brain injury. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15879352

traumatic brain injury post traumatic hypopituitarism PTHP TBI brain low Testosterone hormones brain injury

shared by Nathan Goodyear on 21 Jan 16 - No Cached

Nathan Goodyear on 21 Jan 16

TBI results in isolated or complete pituitary failure (PTHP) in up to 40% of those with TBI.

<div class="cArrow"> </div><div class="cContentInner">TBI results in isolated or complete pituitary failure (PTHP) in up to 40% of those with TBI. </div>

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Administration route-dependent effects of estrogens on IGF-I levels during fixed GH rep... - 0 views

eje-online.org/...709.long

oral estrogen therapy oral estrogen therapy IGF-1 human growth hormone HGH hormone hormones women

shared by Nathan Goodyear on 19 Feb 13 - No Cached

Nathan Goodyear on 19 Feb 13

oral estrogen therapy decreased IGF-1 concentrations in those women taking growth hormone, requiring high dosing of HGH versus that in women using estrogen through a transdermal approach.

<div class="cArrow"> </div><div class="cContentInner">oral estrogen therapy decreased IGF-1 concentrations in those women taking growth hormone, requiring high dosing of HGH versus that in women using estrogen through a transdermal approach.</div>

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Neuroendocrine disorders after... [J Neurol Neurosurg Psychiatry. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18559460

PTHP traumatic brain injury TBI neuroendocrine post-traumatic hypopituitarism brain injury neurology hormone hormones pituitary hypothalamus psychiatry

shared by Nathan Goodyear on 09 Jul 12 - No Cached

Nathan Goodyear on 09 Jul 12

The majority of people with PTHP after TBI remain undiagnosed. The current thought, is that 25% of those with TBI have at least one pituitary hormone deficiency. It does not have to be total pituitary failure. Deficiencies can be isolated.

<div class="cArrow"> </div><div class="cContentInner">The majority of people with PTHP after TBI remain undiagnosed. The current thought, is that 25% of those with TBI have at least one pituitary hormone deficiency. It does not have to be total pituitary failure. Deficiencies can be isolated.</div>

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Growth hormone, insulin-like growth factor-I and th... [Horm Res. 2001] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11786677

HGH growth hormone GH insulin resistance cortisol cortisone obesity adipose tissue adipocytes

shared by Nathan Goodyear on 09 Mar 12 - No Cached

GH deficiency effectively increases cortisol production in key target tissues including liver and adipose tissue, promoting insulin resistance and visceral adiposity
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GH/IGF-I modulation of cortisol metabolism may underpin the pathogenesis of common diseases such as central obesity
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Patients with central obesity but with no evidence of hypopituitarism have relative GH deficiency and it is exciting to speculate that low-dose GH treatment in this group, by inhibiting cortisol generation within omental fat, may offer a novel therapeutic approach.
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Nathan Goodyear on 09 Mar 12

GH plays a key regulating role in obesity. GH deficiency promotes increased cortisone to cortisol production in adipose tissue and liver. This promotes insulin resistance and obesity.

<div class="cArrow"> </div><div class="cContentInner">GH plays a key regulating role in obesity. GH deficiency promotes increased cortisone to cortisol production in adipose tissue and liver. This promotes insulin resistance and obesity. </div>

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Effects of Testosterone and Growth Hormone on the Structural and Mechanical Properties ... - 0 views

press.endocrine.org/...jc.2013-3665

Testosterone bone men male hormones growth hormone GH low T

shared by Nathan Goodyear on 16 Apr 14 - No Cached

Nathan Goodyear on 16 Apr 14

IN men with low Testosterone, Testosterone therapy improved trabecular bone, but not cortical bone. Growth hormone provided no additional benefit. This study looked at men with panhypopituitarism.

<div class="cArrow"> </div><div class="cContentInner">IN men with low Testosterone, Testosterone therapy improved trabecular bone, but not cortical bone. Growth hormone provided no additional benefit. This study looked at men with panhypopituitarism.</div>

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Prevalence of chronic hypopituitarism after blast concussion -- Wilkinson et al. 27 (1)... - 1 views

www.fasebj.org/...935.3

PCS TBI head trauma traumatic brain injury post concussion syndrome concussion hormones pituitary

shared by Nathan Goodyear on 18 Jan 16 - No Cached

Nathan Goodyear on 18 Jan 16

One of the first studies to look at PCS found that 42% of soldiers produced abnormally low hormone production following TBI one year after the injury. This study highlights the potential pituitary dysfunction that can result from TBI.

<div class="cArrow"> </div><div class="cContentInner">One of the first studies to look at PCS found that 42% of soldiers produced abnormally low hormone production following TBI one year after the injury. This study highlights the potential pituitary dysfunction that can result from TBI.</div>

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