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Nathan Goodyear

Kent Holtorf: Long Term Weight Loss - More Than Will Power? - 0 views

  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • f greater than 10, it demonstrates there is a degree of leptin resistance contributing to an inability to lose weight
  • that it is difficult to lose weight with leptin resistance. High carbohydrate diets and in particular high-fructose corn syrup is shown to significantly increase leptin resistance and is a likely mechanism that high fructose corn syrup is associated with obesity
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  • inactive thyroid hormone called thyroxine
  • it is problem inside the cell that the inactive T4 is not converted to T3 but rather to a mirror image of T3 called reverse T3. The reverse T3 has the opposite effect of T3, blocking the effects of T3 and lowering rather than increasing metabolism.
  • Studies are showing that stress and dieting (especially yo-yo dieting) can set this hormone into action as well as chronic illness such as diabetes, chronic fatigue syndrome and fibromyalgia.
  • As soon as the body senses a reduction in calories, the production of reverse T3 is stimulated to lower metabolism
  • With chronic dieting or stress, the body often stays in this "starvation mode" with elevated levels of reverse T3 and decreased levels of T3, which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • Studies are showing that such standard testing will miss 80% of thyroid dysfunction
  • ree T3/reverse T3 ratio
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    Fantastic review by Dr. Holtorf on reverse T3, leptin, and weight loss
Nathan Goodyear

A Randomized Pilot Trial of a Moderate Carbohydrate Diet Compared to a Very Low Carbohy... - 0 views

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    low carb ketogenic diet, high in fat worked better in glycemic control versus DA low fat, medium carbohydrate, calorie restricted diet.
Nathan Goodyear

PLOS ONE: The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice wit... - 0 views

  • This finding strongly supports the efficacy of the KD and HBO2T as therapies to inhibit tumor progression and prolong survival in animals with metastatic cancer.
  • We found that the KD fed ad libitum significantly increased mean survival time in mice with metastatic cancer
  • Ketogenic diets are also known to have an appetite suppressing effect which may contribute to body weight loss
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  • the ketogenic diet may inhibit cancer progression in part by indirect dietary energy restriction
  • KD with HBO2T. Combining these therapies nearly doubled survival time in mice with metastatic cancer,
  • low carbohydrate or ketogenic diets promote weight loss in overweight individuals, they are also known to spare muscle wasting during conditions of energy restriction and starvation
  • dietary-induced therapeutic ketosis in a cancer patient would prevent muscle wasting similarly as it does with athletes undergoing intense exercise
  • when given as an adjuvant treatment to advanced cancer patients, the KD improves quality of life and enhances the efficacy of chemotherapy treatment in the clinic
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    mouse study finds that ketogenic diet plus hyperbaric O2 treatment prolongs survival.
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Nathan Goodyear

Long-Term Immunomodulatory Effects of a Mediterranean Diet in Adults at High ... - 0 views

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    Mediterranean diet found to reduce hsCRP, IL-6, TNF-alpha, and MCP in high-risk adults out to 5 years!  This study compared the Mediterranean diet to a low fat diet.
healthwiseindian

Diet tips for healthy weight loss - 0 views

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    Weight loss is an important topic of worry. Not all kinds of dieting practices are helpful in achieving a healthy weight loss. Follow the advice of Dr. Binita who has compiled a comprehensive study about weight loss. At Healthwise Indian, we help in giving health guidance to people in order to improve their lifestyle.
Nathan Goodyear

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Re... - 0 views

  • Long-term DPs play a large role in determining the selective environment that the gut microbiota faces, ultimately influencing the composition and diversity of taxa maintained within the gut microbial community
  • Americans consuming unrestricted diets maintained less diverse fecal microbiota than those of individuals adhering to a plant-rich diet with restricted caloric intake
  • Experiments in mice have shown that multigenerational exposure to a Western diet poor in “microbiota-accessible carbohydrates” can lead to extirpation of specific bacterial lineages
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    Diet is the key to gut microbe diversity.  Gut microbes are key to maintaining optimal cellular metabolism.  Nutrition can be a prescription for improving and reprogramming gut bacteria.
Nathan Goodyear

Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet - NEJM - 0 views

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    mediterranean and low-carb diets are effective diets to aid weight loss
Nathan Goodyear

ScienceDirect - American Psychologist : Medicare's Search for Effective Obesity Treatme... - 0 views

  • These studies show that one third to two thirds of dieters regain more weight than they lost on their diets, and these studies likely underestimate the extent to which dieting is counterproductive because of several methodological problems,
  • there is little support for the notion that diets lead to lasting weight loss or health benefits.
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    "diet' show no lasting benefit in weight loss and health benefits.  In fact, 66% of individuals weigh more than they started after 2 years.
Nathan Goodyear

Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes. - PubM... - 0 views

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    low carb, high fat, ketogenic diet outperformed low calorie diet in people with type II diabetes
Nathan Goodyear

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice: Cell Metabolism - 0 views

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    study of mice finds that high fat diet changes genetic expression, epigenetics, to increase lifespan of mice by 13%.
Nathan Goodyear

Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skelet... - 0 views

  • short-term HFO introduces DNA methylation changes on a genome-wide scale in human skeletal muscle
  • These changes were only partly reversed after 6–8 weeks
  • The induction of DNA methylation changes after 5 days of HFO supports the growing awareness of DNA methylation as a dynamic signal that is possibly relevant to short-term day-to-day metabolic adaptations, including acute exercise
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  • Diverging DNA methylation levels between elderly, but not young, genetically identical twins indicate that environmental exposures throughout life may permanently influence DNA methylation, suggesting some preservation of de novo DNA methylation in adults
  • our finding of a slow reversibility rate indicates the demethylation process may be somewhat impeded compared with the induction of methylation changes by diet, which could have implications for the preservation or build-up of CpG methylation over time
  • A slow reversibility of DNA methylation induced by carcinogenic agents has likewise been observed due to ingestion of high-fat diets in rodents
  • the relationship between DNA methylation and gene expression is not always straightforward
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    Study finds variability of methylation and some genetic expression alteration with high fat diet.  Restated, what you eat interacts with your DNA to alter genetic expression.  This has implications on initiation of therapy as well as response to therapy.
fitspresso

https://www.sightcare-co.com/ - 0 views

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Nathan Goodyear

Relationship Between Healthy Diet and Risk of Cardiovascular Disease Among Patients on ... - 0 views

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    This study proves that the foundation of our current health problem is our diet.  Eat better!  In this study, individuals with CVD, had a significant reduction in recurrent CVD events with a simple change in diet.  The amazing thing it was above and beyond that of medications.
Nathan Goodyear

Divergent trends in obesity and fat intake patterns... [Am J Med. 1997] - PubMed - NCBI - 0 views

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    Fat intake is inversely associated with the obesity trend.  During, the 80's, a low fat diet was all the craze.  However, the obesity trend increased with the incorporation of the the low fat diet in America.
Nathan Goodyear

The Neuropharmacology of the ketogenic diet - 0 views

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    review of the biochemistry of ketogenic diet in the brain.
Nathan Goodyear

Androgens in Polycystic Ovary Syndrome: The Role of Exercise and Diet - 0 views

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    Though this article looked at diet and exercise on PCOS, this article gives a great review of the pathophysiology of PCOS. This study did show that diet and exercise were effective in lowering androgens and improving insulin resistance.
Nathan Goodyear

Decrease of serum total and free testosterone during a low-fat high-fibre diet - 0 views

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    diet effects Testosterone.  In this small study, a lower fat, increased fiber diet resulted in a decreased free and total Testosterone.
Nathan Goodyear

Dietary carbohydrate restriction as the first approach in diabetes management: Critical... - 0 views

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    Excellent article on the ketogenic diet and the treatment of diabetes.   A ketogenic diet here was defined as < 10% carbs
Nathan Goodyear

Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tis... - 0 views

  • SCFAs play a dual role both as substrates for metabolism and as signaling molecules
  • SCFAs can be either directly converted (acetate) or oxidized (propionate and butyrate) to acetyl-Co
  • Here we demonstrate that microbial colonization regulates global histone acetylation and methylation in multiple host tissues in a diet-dependent manner
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  • complex functional interactions between diet, gut microbiota, and host health.
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    diet changes gut microbiota, which changes genetic expression--it is called epigenetics.  This is an animal study.
Nathan Goodyear

Diet and Risk of Colorectal Cancer Subtypes Classified by F nucleatum | Colorectal Canc... - 0 views

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    Study finds Diet effect colon cancer risk through gut bacteria. Diet higher in fiber and whole grains found to have lower risk of F nucleatum + colon cancer.
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