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Nathan Goodyear

Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment... - 0 views

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    DHA supplementation in mother increased DHA phosopholipid levels in infant; though no change in neurodevelopment was noted
Nathan Goodyear

Health Care Overhaul May Push Employee Benefits Shift - 0 views

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    The future of Employee benefits is changing
Nathan Goodyear

Arch Gen Psychiatry -- Abstract: Neural Correlates of Food Addiction, April 4, 2011, Ge... - 0 views

  • Similar patterns of neural activation are implicated in addictive-like eating behavior and substance dependence: elevated activation in reward circuitry in response to food cues and reduced activation of inhibitory regions in response to food intake.
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    Similar neurochemical changes with food as seen in other addictions
Nathan Goodyear

Axillary Dissection vs No Axillary Dissection in Women With Invasive Breast Cancer and ... - 0 views

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    axillary lymph node dissection in breast cancer patients did not change survival rate when compared to sentinal Lymph node removal
Nathan Goodyear

Ineffectiveness of human chorionic gonadotropin in... [Am J Clin Nutr. 1976] - PubMed r... - 0 views

  • e sought to duplicate the Asher-Harper study (1973)
  • here was no statistically significant difference in the means of the two groups in number of injections received, weight loss, percent of weight loss, hip and waist circumference, weight loss per injections, or in hunger ratings. HCG does not appear to enhance the effectiveness of a rigidly imposed regimen for weight reduction
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    no improvement in weight loss with HCG injections above that in dietary changes. This isa duplication of the initial Asher-Harper study in 1973 that did show improvement in 20 women.  
Nathan Goodyear

Day-to-day differences in cortisol levels and mola... [Yonsei Med J. 2010] - PubMed result - 0 views

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    salivary cortisol and DHEA levels change. This reflects the day to day, week to week stressors.
Nathan Goodyear

Caution on the use of saliva measurements to monitor absorption of progesterone from tr... - 0 views

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    conclusion incorrect.  blood testing is a poor testing method of transdermal progesterone therapy would be the more accurate conclusion.  Other studies have shown that transdermal progesterone therapy raises progesterone in saliva when blood levels show no change.
Nathan Goodyear

Normal gut microbiota modulates brain development and behavior - 0 views

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    mice model study that shows how gut bacterial balance can alter neurochemistry and cause behavior/developmental changes
Nathan Goodyear

Access : Effect of three consecutive meals on the physicochemical properties of HDL and... - 0 views

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    repetitive post-meal reveals elevated lipids promote an atherogenic change in HDL and LDL
Nathan Goodyear

ScienceDirect - Life Sciences : Direct Radioimmunoassay (RIA) of salivary testosterone:... - 0 views

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    salivary testosterone proven statistically reliable method to detect changes in the biologically active hormone.
Nathan Goodyear

Is the use of cholesterol in mortality risk algorithms in clinical guidelines valid? Te... - 0 views

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    here is the full article on the need for change in how we view cholesterol.  This is from the Norwegian HUNT 2 study that showed that cholesterol up to 270 reduced cardiovascular disease mortality
Nathan Goodyear

Tissue-Specific Increases in 11β-Hydroxysteroid Dehydrogenase Type 1 in Norma... - 0 views

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    11 beta HSD type 1 increases in menopause in normal weight women.  This may explain some of the metabolism changes seen in women post-menopause.
Nathan Goodyear

CARDIOVASCULAR DISEASE IN TRANSSEXUAL PERSO... [Eur J Endocrinol. 2014] - PubMed - NCBI - 0 views

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    The point of this study post is not the focus on the sex change, but that estrogen dosing in men is associated with increased CVD. This is known from the other literature.
Nathan Goodyear

Low Levels of Free Testosterone Correlated wi... [Horm Metab Res. 2014] - PubMed - NCBI - 0 views

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    Interesting study looked at Total Testosterone (TT) and free Testosterone (FT) in older men in BMD assessment.  The authors found no change in TT, but a significant decline in free Testosterone.  This fits with other research pointing to free Testosterone as a better functional assessment tool.
Nathan Goodyear

Race differences in obesity and its relationship to the sex hormone milieu : Hormone Mo... - 0 views

  • increased abdominal and visceral adipose tissue (VAT) – found in women and marked by low sex hormone binding globulin (SHBG) and high bioavailable testosterone (BT) – is related to the metabolic risk profile
  • In men, increased BT is related to decreased abdominal obesity and a decrease in the metabolic risk profile
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    Only abstract available here.  Race (black vs white) is associated with changes in obesity effects on adrogenicity, particularly in women.  One wonders if this is a result of other variables i.e.vitamin D.
Nathan Goodyear

The endurance athletes heart: acute stress and chronic adaptation -- George et al. 46 (... - 0 views

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    acute and chronic heart changes to endurance training/events.
Nathan Goodyear

Testosterone does not adversely affect fibrinogen or tissue plasminogen activator (tPA)... - 0 views

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    Thrombosis and cardiovascular risk is a hot topic in Testosterone therapy in men.  This study showed that topical "physiologic" Testosterone therapy provided no negative effects on the coagulation system.  No changes were documented in tPA, PAI-1, and fibrinogen levels in men with chronic stable angina.  This stands in contrast to supra-physiologic therapy of Testosterone that leads to hypofibrinogenemia.
Nathan Goodyear

Secular trends in sex hormones and fractures in menand women - 0 views

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    Study finds lower serum Testosterone levels in men in 2008 compared to men in 1995 of similar ages at time of assessment.  No change in fracture incidence was found.
Nathan Goodyear

Effect of resistance exercise on muscle steroidogenesis | Journal of Applied Physiology - 0 views

  • skeletal muscle cell cultures incubated with DHEA produced testosterone in a DHEA dose-dependent manner
  • Muscle joins a growing list of tissues found to be capable of steroidogenesis
  • testosterone appears to have a role in the maintenance of muscle mass in women, although the importance of this role has not yet been fully established.
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  • Circulating testosterone concentrations are generally elevated following a bout of resistance exercise in men (24, 31, 46, 52), whereas findings for the effect of resistance exercise on circulating testosterone in women are equivocal, with increases (10, 42) and no changes observed (22, 31)
  • swimming (51) and treadmill running (2) can significantly increase muscle testosterone concentrations in male and female rats
  • This upregulation of muscle testosterone in rats appears, at least in part, to be due to an increase in 3β-HSD and 17β-HSD type 1 expression
  • The primary finding in this study was that muscle steroidogenesis (i.e., testosterone production) in highly resistance-trained humans was not affected by an acute bout of heavy resistance exercise
  • A secondary finding was that the apparent molecular mass of 17β-HSD type 3 was increased following a single bout of heavy resistance exercise.
  • No differences were found for muscle testosterone or steroidogenic enzyme (17β-HSD type 3 and 3β-HSD types 1 and 2) concentrations between sexes or in response to resistance exercise
  • In conclusion, heavy resistance exercise did not induce changes in muscle steroidogenesis as measured by muscle concentrations of testosterone, 3β-HSD types 1 and 2, and 17β-HSD type 3 in highly resistance-trained young men and women.
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    Resistance exercise did not increase muscle concentrations of Testosterone in men or women.  The individuals in this study were actively training.  These were not sedentary individuals.
Nathan Goodyear

Recovery after heavy resistance exercise... [J Strength Cond Res. 2011] - PubMed - NCBI - 0 views

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    "Heavy resistance exercise" associated with acute increase in TT and fT in men.  No changes were see in basal T and fT in recovery or AR.  The recovery phase was estimated to take 6 days.
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