Group items tagged

IV vitamin K3 shown to provide synergy with IV vitamin C in vitro study of cancer cells.

IV Vitamin C improves endothelial vasodilation in essential hypertension.  The Vitamin C reduces the oxygen free radicals which allowed eNOS to increase NO production.  Two take homes: oxygen free radicals may be responsible for the endothelial dysfunction that leads to essential hypertension and vitamin C, particularly IV, can be used to counter this process.  Other studies have shown IV vitamin C to be anti-hypertensive in its action.

vitamin C found to decrease inflammatory signaling.  In this study, they found a decrease in GM-CSF induction of  ROS due to vitamin C.  This was an in vitro study, but another flag in the claim that vitamin C reduces inflammation and ROS.

current vitamin B12 recommendations are too low.  Proper vitamin B12 biomarker testing reveals this fact. The problem is most people fall prey to the lack of knowledge behind simple serum levels.  Simple B12 serum levels are woefully inadequate. Insurance would rather one stay with inadequate testing to save money, rather than actually read the science to learn about new testing.

Higher vitamin D levels associated with lower death rates from breast cancer.  In fact, people with the highest levels of vitamin D had death rates cut in half.  The authors point to 3 ares that vitamin D has a positive effect against cancer: differentiation, apoptosis, and angiogenesis.

old study finds oral vitamin C destroyed substantial amount of B12.  This is the reason vitamin B 12 is given when vitamin C is given.

study finds "high dose" IV vitamin C benefited 3 of 5 patients in short 4 week study.  The "high dose" was not high dose at all, so that fact that a low dose of IV vitamin C will benefit dermatomysotis in over 50% of the patients in this very small study points to the question, what if actually high dose vitamin C is used.

IV vitamin C associated with prolonged survival in 3 patients with different cancers.  Peak serum levels reached 14,000 micromol/L, which levels above the 1,000 micro mol/L (cancer cell cytotoxic threshold) were maintained for hours

IV vitamin C found to significantly increased serum levels beyond that of oral.  IV vitamin C is the only route that should be administered for patients with cancer.  IVC at 50 grams showed peak C concentration at 13,400 micromol/L.  Levels of at least 400-600 are required for tumorcidal effects.  In addition, IV vitamin C increased NO release and decreases b/p

So help me out here:  If IV vitamin C has been shown to prolong time to cancer relapse, aid in reducing tumor size, improve survival with chemotherapy, improve quality of life, improve physical function, reduce chemo side effects, improve energy, reduce nausea, aid insomnia, reduce constipation, and improve depression in cancer patient--then why does the author say that IV vitamin C is contentious?  Add that IV vitamin C has not been implicated in any deaths in cancer therapy.  Contrast that with chemotherapy.  Why again is this contentious?  Whom is best served by this being contentious?

This study, small pilot, showed that they were able to lower inflammation in those suffering from RA, through high dose vitamin C IV therapy. This study stopped at 25 gms. The vitamin C is a scavenger of ROS and ROS stimulates inflammation through NF-kappaB. This is how vitamin C can reduce inflammation.

Dose dependent vitamin D impact on fat.  Low vitamin D concentrations associated with fat adipogenesis.  Higher vitamin D concentrations inhibited adipogenesis.

Vitamin D supplementation in those individuals with SLE found to benefit these patients.   Vitamin D found to reduce TH1 and Th17 activity.  It also was found to decrease memory B cells and auto-antibodies.  Also of note is the level of vitamin D after therapy-only at 51.4 at 2 months and 41.5 at 6 months.

Only abstract available here.  The quote that "the toxicity of vitamin E is very low" tells the story.  Always have levels evaluated to ensure need.  In this review of human studies, doses up to 3,200 IU daily "led to no consistent adverse effects".  Also consider the effects of vitamin K effects in those on vitamin E therapy.

Vitamin B12, methyl cobalamin, is very important in lowering homocysteine levels through methionine synthase.  The VISP trial did not show efficacy in the intention to treat analysis.  However, analysis of the efficacy reveals that many clients had too low of vitamin B12 levels due to malabsorption and vitamin B12 levels should have been higher in the VISP intention to treat.

IV vitamin C and vitamin E was found to lower the mortality rate in those with critical illness at the 28 day mark.  This study showed the safety and efficacy of IV vitamin C and vitamin E in those critically ill.

only high dose IV vitamin C shown to produce high plasma vitamin C concentrations compared to oral vitamin c.

Obesity is associated with decreased vitamin D3 levels. One would think that an increase in surface area would increase Vitamin D levels, but actually, the increase in fat accumulates the fat soluble vitamin D3.

Meta-analysis finds that for every oral daily intake of 100 mg vitamin C, the risk of total mortality was decreased by 27% and the breast cancer specific mortality was decreased by 22%.  A lot of potential variables that can play into this equation.  However, oral vitamin C is poorly bioavailable, yet according to this meta-analysis, does provide significant health benefits and even prevention.  If health and breast cancer prevention is a goal, then vitamin C needs to play a role in your daily intake.

Low vitamin D levels or the receptors for vitamin D appear to result in an increase in Th17 cells.  An increase in Th17 cells will lead to an imbalance with Treg cells and this imbalance is associated with Lupus and other autoimmune processes.  Vitamin D inhibits Th17 cell activation.