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Nathan Goodyear

Low testosterone in a young combat veteran with dual diagnosis and ... - PubMed - NCBI - 0 views

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    Low T found in young combat veteran with PTSD and SI.  This is no surpass as there is significant HPA dysfunction in these men/women.  The overwhelming cortisol response and resultant PTSD will shut down endogenous Testosterone production.  I have seen this in several combat veterans.
Nathan Goodyear

Correlations between serum and salivary hormona... [J Sports Sci. 2008] - PubMed - NCBI - 0 views

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    salivary cortisol and DHEA correlates well with serum levels before and after exercise.  Testosterone, in this study did not.
Nathan Goodyear

Direct Inhibitory Effect of Glucocorticoids upon Testicular Luteinizing Hormone Recepto... - 0 views

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    glucocorticoids inhibit Testosterone production via down regulation of LH receptors at the level of the testicles.
Nathan Goodyear

Altered Cortisol Metabolism in Polycystic Ovary Syndrome: Insulin Enhances 5α... - 0 views

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    lean women with PCOS found to have reduced 11 beta-HSD1 and increased 5 alpha reductase activity.  This, in part, is associated with the elevated cortisol and androgens in these women.
Nathan Goodyear

Chronic distress and acute vascular stress r... [J Hum Hypertens. 2013] - PubMed - NCBI - 0 views

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    Low T and high cortisol associated with increased ischemic events and elevated blood pressure.
Nathan Goodyear

Cortisol, Testosterone, and Coronary Heart Disease - 0 views

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    Cortisol:Testosterone ratio associated with statistical increase risk of ischemic heart disease. This was mediated through the insulin resistance.
Nathan Goodyear

Cortisol, Testosterone, and Coronary Heart Disease - 0 views

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    high cortisol:testosterone shown to increase CHD.  This is felt to be through insulin dysregulation.
Nathan Goodyear

Inflammation and cortisol response in coronary artery disease: Annals of Medicine: Vol ... - 0 views

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    Inflammation disrupts HPA axis.  This is no surprise as we Know that inflammation can disrupt Testosterone in men and progesterone production in women.  This study suggests that this HPA axis disruption contributes to CAD.
Nathan Goodyear

Reduced testosterone and adrenal C19 steroid levels in obese men. - PubMed - NCBI - 0 views

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    Decreased adrenal steroid production occurred in men with obesity.  Estrone positively correlated.
Nathan Goodyear

http://joe.endocrinology-journals.org/content/170/2/413.full.pdf - 0 views

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    Leptin shown to inhibit steroid hormone synthesis in the gonads via inhibition of 17beta-HSD.  This is in addition to other reports of inhibition of 17,20 lyase, adrenal cortisol inhibition, inhibition of CRF, and inhibition of LH/FSH.
Nathan Goodyear

ScienceDirect - Pathologie Biologie : Saliva assays in clinical and research biology - 0 views

  • the saliva concentration reflects the free blood concentration.
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    saliva testing of stress and sex hormones have been utilized since the early 1980's and described as "well validated" in the literature.
Nathan Goodyear

The Diagnostic Applications of Saliva- A Review - 0 views

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    Fantastic article on the review of the clinical use of saliva testing.  Of note, is the extensive documentation of the validation studies of hormone saliva testing.  Clearly, if a physician is against saliva testing, it is because of a lack of knowledge on the subject.
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