Group items tagged NEJM - Dr. Goodyear

Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy -... - 0 views

www.nejm.org/...NEJMsa065779

NEJM antidepressants depression

shared by Nathan Goodyear on 13 Jan 12 - No Cached

According to the published literature, it appeared that 94% of the trials conducted were positive. By contrast, the FDA analysis showed that 51% were positive
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Nathan Goodyear on 13 Jan 12

NEJM reanalyzed the results from 12 antidepressant studies involving over 12,000 patients and found that 40% of studies that found no benefit for antidepressants were omitted. This seriously altered the statistics and is obvious manipulation of data. This brings the current recommendations on antidepressants into serious question.

<div class="cArrow"> </div><div class="cContentInner">NEJM reanalyzed the results from 12 antidepressant studies involving over 12,000 patients and found that 40% of studies that found no benefit for antidepressants were omitted. This seriously altered the statistics and is obvious manipulation of data. This brings the current recommendations on antidepressants into serious question.</div>

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Losing Weight - An Ill-Fated New Year's Resolution - NEJM - 0 views

www.nejm.org/...NEJM199801013380109

obesity weight loss

shared by Nathan Goodyear on 16 Oct 16 - No Cached

Nathan Goodyear on 16 Oct 16

weight loss programs notoriously unsuccessful.

<div class="cArrow"> </div><div class="cContentInner">weight loss programs notoriously unsuccessful.</div>

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Sensory Neuropathy from Pyridoxine Abuse - NEJM - 0 views

www.nejm.org/...nejm198308253090801

neuropathy vitamin B6 B6 vitamin vitamins

shared by Nathan Goodyear on 26 Jun 12 - No Cached

Nathan Goodyear on 26 Jun 12

older study. High dosage vitamin B6 associated with short term ataxia and and neuropathy. This resolved following removal. Dosage unknown.

<div class="cArrow"> </div><div class="cContentInner">older study. High dosage vitamin B6 associated with short term ataxia and and neuropathy. This resolved following removal. Dosage unknown.</div>

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The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in No... - 0 views

www.nejm.org/...NEJM199607043350101

Testosterone doping muscle mass strength

shared by Nathan Goodyear on 18 Mar 14 - No Cached

Nathan Goodyear on 18 Mar 14

Study finds that massive doping of Testosterone, 600 mg weekly, results in increase muscle mass and performance with strength training. This dosing amounts to about 100 mg daily compared to the 5-10 mg of peak daily production of a young man.

<div class="cArrow"> </div><div class="cContentInner">Study finds that massive doping of Testosterone, 600 mg weekly, results in increase muscle mass and performance with strength training. This dosing amounts to about 100 mg daily compared to the 5-10 mg of peak daily production of a young man.</div>

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Effects of Thyroxine as Compared with Thyroxine plus Triiodothyronine in Patients with ... - 0 views

www.nejm.org/...NEJM199902113400603

Armour T4 T3 synthroid hypothyroidism hypothyroid thyroid

shared by Nathan Goodyear on 01 Aug 11 - No Cached

Nathan Goodyear on 01 Aug 11

Armour Thyroid (T4 and T3 combined) provides better symptom control when compared to synthroid alone (T4)

<div class="cArrow"> </div><div class="cContentInner">Armour Thyroid (T4 and T3 combined) provides better symptom control when compared to synthroid alone (T4)</div>

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Elevated Serum Thyrotropin in Thyroxine-Treated Patients with Hypothyroidism Given Sert... - 0 views

www.nejm.org/...NEJM199710023371415

zoloft SSRI hypothyroid hypothyroidism

shared by Nathan Goodyear on 20 Dec 10 - No Cached

Nathan Goodyear on 20 Dec 10

zoloft lowers thyroid function

<div class="cArrow"> </div><div class="cContentInner">zoloft lowers thyroid function</div>

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Thyroid Hormone Replacement - One Hormone or Two? - NEJM - 0 views

www.nejm.org/...NEJM199902113400611

thyroid T4 T3 armour

shared by Nathan Goodyear on 17 Dec 10 - No Cached

Nathan Goodyear on 17 Dec 10

Patients feel better taking both T4 and T3 compared to those taking just T4

<div class="cArrow"> </div><div class="cContentInner">Patients feel better taking both T4 and T3 compared to those taking just T4</div>

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The Effect of Dietary Supplementation with n-3 Polyunsaturated Fatty Acids on the Synth... - 0 views

www.nejm.org/...NEJM198902023200501

Omega-3 inflammation anti-inflammatory

shared by Nathan Goodyear on 11 Feb 11 - No Cached

Nathan Goodyear on 11 Feb 11

Omega-3 is anti-inflammatory

<div class="cArrow"> </div><div class="cContentInner">Omega-3 is anti-inflammatory</div>

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Drug-Related Lupus - NEJM - 0 views

www.nejm.org/...NEJM198806023182209

drug induced lupus

shared by Nathan Goodyear on 16 Mar 11 - No Cached

Nathan Goodyear on 16 Mar 11

Drug induced lupus exceeds 70 known drugs

<div class="cArrow"> </div><div class="cContentInner">Drug induced lupus exceeds 70 known drugs</div>

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Plasma Homocysteine Levels and Mortality in Patients with Coronary Artery Disease - NEJM - 0 views

www.nejm.org/...NEJM199707243370403

homocysteine mortality cardiovascular disease CAD risk

shared by Nathan Goodyear on 03 Aug 11 - No Cached

Plasma total homocysteine levels are a strong predictor of mortality in patients with angiographically confirmed coronary artery disease
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Nathan Goodyear on 03 Aug 11

elevated homocysteine strong predictor of mortality

<div class="cArrow"> </div><div class="cContentInner">elevated homocysteine strong predictor of mortality</div>

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Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain - NEJM - 0 views

www.nejm.org/...NEJM198802253180802

obese weight loss overweight metabolic rate

shared by Nathan Goodyear on 11 Jul 11 - No Cached

Nathan Goodyear on 11 Jul 11

Seems obvious, but lower metabolic rate increases obesity rate

<div class="cArrow"> </div><div class="cContentInner">Seems obvious, but lower metabolic rate increases obesity rate</div>

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High-Dose Vitamin C versus Placebo in the Treatment of Patients with Advanced Cancer Wh... - 0 views

www.nejm.org/...NEJM198501173120301

Mayo study Mayo vitamin C oral vitamin C

shared by Nathan Goodyear on 13 Mar 22 - No Cached

Tumors: Wounds That Do Not Heal | NEJM - 0 views

www.nejm.org/...NEJM198612253152606

cancer wounds that don't heal wounds that will not heal

shared by Nathan Goodyear on 08 Jan 23 - No Cached

Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the ... - 0 views

www.nejm.org/...NEJMoa021993

CRP c-reactive protein LDL cholesterol cardiovascular disease cardiovascular events

shared by Nathan Goodyear on 15 Jan 13 - No Cached

Nathan Goodyear on 15 Jan 13

CRP is more predictive than LDL in predicting cardiovascular events.

<div class="cArrow"> </div><div class="cContentInner">CRP is more predictive than LDL in predicting cardiovascular events.</div>

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Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin ... - 0 views

www.nejm.org/...NEJMoa012512

diabetes lifestyle changes metformin

shared by Nathan Goodyear on 07 Dec 10 - No Cached

Nathan Goodyear on 07 Dec 10

lifestyle changes more effective than metformin in Type 2 diabetes

<div class="cArrow"> </div><div class="cContentInner">lifestyle changes more effective than metformin in Type 2 diabetes</div>

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Normal Fasting Plasma Glucose Levels and Type 2 Diabetes in Young Men - NEJM - 0 views

www.nejm.org/...NEJMoa050080

fasting plasma glucose diabetes

shared by Nathan Goodyear on 15 Mar 12 - No Cached

Nathan Goodyear on 15 Mar 12

Fasting glucose levels >90 require treatment. Don't wait until they increase above 100, damage is actively occurring in the kidneys at levels above 90. institute dietary/lifestyle changes at any point above 84.

<div class="cArrow"> </div><div class="cContentInner">Fasting glucose levels >90 require treatment. Don't wait until they increase above 100, damage is actively occurring in the kidneys at levels above 90. institute dietary/lifestyle changes at any point above 84.</div>

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Circulating Endothelial Progenitor Cells and Cardiovascular Outcomes - NEJM - 0 views

www.nejm.org/...NEJMoa043814

EPCs endothelial progenitor cells CVD cardiovascular disease cardiovascular events cardiovascular risk heart cardiology

shared by Nathan Goodyear on 10 Jul 12 - No Cached

Nathan Goodyear on 10 Jul 12

Endothelial progenitor cells predict cardiovascular events and mortality. Higher EPCs associated with a 70% less mortality from cardiovascular causes.

<div class="cArrow"> </div><div class="cContentInner">Endothelial progenitor cells predict cardiovascular events and mortality. Higher EPCs associated with a 70% less mortality from cardiovascular causes.</div>

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Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet - NEJM - 0 views

www.nejm.org/...NEJMoa0708681

weight weight loss mediterranean loss diet overweight obesity

shared by Nathan Goodyear on 20 Dec 11 - No Cached

Nathan Goodyear on 20 Dec 11

mediterranean and low-carb diets are effective diets to aid weight loss

<div class="cArrow"> </div><div class="cContentInner">mediterranean and low-carb diets are effective diets to aid weight loss</div>

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Long-Term Persistence of Hormonal Adaptations to Weight Loss - NEJM - 0 views

www.nejm.org/...NEJMoa1105816

rebound weight gain overweight obesity hormones hormone loss

shared by Nathan Goodyear on 08 Nov 11 - No Cached

Nathan Goodyear on 08 Nov 11

rebound weight gain has hormone component

<div class="cArrow"> </div><div class="cContentInner">rebound weight gain has hormone component</div>

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Adverse Events Associated with Testosterone Administration - NEJM - 0 views

www.nejm.org/...NEJMoa1000485

testosterone therapy treatment replacement low T cardiovascular events

shared by Nathan Goodyear on 01 Feb 12 - No Cached

Nathan Goodyear on 01 Feb 12

Testosterone therapy shown to increase cardiovascular events in elderly men. No comment in study if they evaluated the aromatization of the replacement therapy to estrogen. I anticipate that this would explain the increase events.

<div class="cArrow"> </div><div class="cContentInner">Testosterone therapy shown to increase cardiovascular events in elderly men. No comment in study if they evaluated the aromatization of the replacement therapy to estrogen. I anticipate that this would explain the increase events.</div>

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