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Nathan Goodyear

Thyroid Hormone and Cardiac Disease: From Basic Concepts to Clinical Application - 0 views

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    Low T3 post MI is associated with increased CHF, morbidity and mortality.  Article discusses thyroid hormones and cardiac function/remodeling post infarct.  The article also lays the ground work for a new study of T3 in patients post MI to be followed for 6 months.
Nathan Goodyear

Small Differences in Thyroid Function May Be Important for Body Mass Index and the Occu... - 0 views

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    Even small movements of thyroid function within the "reference rage of normal" is associated with significant metabolic, BMI, and weight effects.
Nathan Goodyear

Effects of Hypo- and Hyperthyroidism on Noradrenergic Activity and Glycerol Concentrati... - 0 views

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    Thyroid hormone increased localized norepinephrine production and liposlys resulting in decreases SQ adipose tissue compared to hypothyroid.  This study showed a localized effect of adipose tissue by thyroid hormone. 
Nathan Goodyear

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individua... - 0 views

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    TSH positively associated with increase stroke in those adults less than 65.
Nathan Goodyear

Levothyroxine therapy and serum free thyroxine and... [J Endocrinol Invest. 2002] - Pub... - 0 views

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    T4 therapy (synthroid) alone does not increase serum free T3 concentrations in many patients
Nathan Goodyear

Thyroid Hormone Replacement Therapy in Primary Hypothyroidism: A Randomized Trial Compa... - 0 views

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    study shows end points, designed in study, showed no change with combined thyroid therapy; but patients preferred combined therapy.
Nathan Goodyear

[Functional states of pituitary-ovary, adrenal and... [Zhonghua Fu Chan Ke Za Zhi. 1998... - 0 views

  • CONCLUSION: It appears that ovarian androgen excess in women with PCOS is mainly LH-dependent in Group 1 and insulin-dependent in Group 2. Enhanced adrenal activity may contribute to both hyperandrogenism and insulin resistance in this syndrome, and subclinical hypothyroidism may exist in affected subjects, especially of Group 1.
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    PCOS is not a birth control pill deficiency, but a complex hormonal imbalance
Nathan Goodyear

Peripheral metabolism of thyroid hormones: a revie... [Altern Med Rev. 2000] - PubMed r... - 0 views

  • The common feature of these disorders is a low level of circulating T3, with generally normal to slightly elevated blood T4 levels and either normal or slightly suppressed TSH levels. This pattern of altered thyroid hormone levels is generally agreed to be a result of impairment in extra-thyroidal peripheral metabolism
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    thyroid replacement is not just about T4 (synthroid); but about T3, which is 5.4 x more potent
Nathan Goodyear

Effects of Thyroid Hormone on the Cardiovascular System -- Fazio et al. 59 (1): 31 -- R... - 0 views

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    Great article on how the thyroid helps to regulate the heart
Nathan Goodyear

Thyroid Disease and the Heart -- Klein and Danzi 116 (15): 1725 -- Circulation - 0 views

  • The importance of the recognition of the effects of thyroid disease on the heart also derives from the observation that restoration of normal thyroid function most often reverses the abnormal cardiovascular hemodynamics
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    T3 and normalization of thyroid function improves heart function in those with significant heart disease
Nathan Goodyear

[Serum thyroid hormone levels correlate with cardi... [J Cardiol. 1993] - PubMed result - 0 views

  • Patients with ventricular tachycardia demonstrated significantly lower serum values of FT3 and FT3/FT4, and significantly higher values of rT3. Serum thyroid hormone levels can provide a quantitative index for evaluating the severity of chronic heart failure and predicting ventricular tachycardia.
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    Full thyroid evaluation, not TSH or just T4, is predictive in severity of CHF and heart tachycardia
Nathan Goodyear

Safety and hemodynamic effects of intravenous trii... [Am J Cardiol. 1998] - PubMed result - 0 views

  • Acute intravenous administration of triiodothyronine is well tolerated in patients with advanced heart failure
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    T3 beneficial in those with acute heart failure
Nathan Goodyear

Thyroid hormone abnormalities in heart failure: po... [Thyroid. 1996] - PubMed result - 0 views

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    T3 improves cardiac output in those with heart failure
Nathan Goodyear

Acute Effects of Triiodothyronine (T3) Replacement Therapy in Patients with Chronic Hea... - 0 views

  • In DC patients, short-term synthetic L-T3 replacement therapy significantly improved neuroendocrine profile and ventricular performance
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    T3 provides significant improvement in cardiac function in those with dilated cardiomyopathy
Nathan Goodyear

Association between increased levels of reverse tr... [Am J Med. 2001] - PubMed result - 0 views

  • CONCLUSION: Determination of reverse T3 levels may be a valuable and simple aid to improve identification of patients with myocardial infarction who are at high risk of subsequent mortality.
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    reverse T3 predictive of increased mortality in people with myocardial infarctions
Nathan Goodyear

Proinflammatory cytokines inhibit the expression and function of human type I 5'-deiodi... - 0 views

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    inflammation inhibits thyroid function
Nathan Goodyear

Serum concentrations of total T4, T3, reverse T3 a... [Hum Nutr Clin Nutr. 1985] - PubM... - 0 views

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    poor nutrition leads to low free T3 in tissue which lowers cellular metabolism which leads to obesity
Nathan Goodyear

Fortnightly review: Hypothyroidism: screening and subclinical disease -- Weetman 314 (7... - 0 views

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    TSH > 2 may not be a normal in many individuals
Nathan Goodyear

Low Serum Triiodothyronine (T3) and Hypothyroidism in Anorexia Nervosa -- CROXSON and I... - 0 views

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    low t3 conversion implicated in Anorexia Nervosa
Nathan Goodyear

Free T4, Free T3, and Reverse T3 in Critically III, Thermall... : The Journal of Trauma - 0 views

  • Significant suppression of serum concentrations of 3,5,3'-triiodothyronine (T3) and elevation of serum concentrations of 3,3',5'-triiodothyronine (rT3) were seen
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    low free T3: elevated reverse T3 in critically ill patients
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