Group items tagged male hormones' hormones - Dr. Goodyear

http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/Reprod... - 0 views

www.fda.gov/...UCM412536.pdf

low T low Testosterone Testosterone male hormones

shared by Nathan Goodyear on 16 May 16 - No Cached

Nathan Goodyear on 16 May 16

Testosterone has moved from therapy to recreational for many men. The 50-25-21 rule.

<div class="cArrow"> </div><div class="cContentInner">Testosterone has moved from therapy to recreational for many men. The 50-25-21 rule.</div>

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http://www.eje-online.org/content/173/2/167.full.pdf - 0 views

www.eje-online.org/...167.full.pdf

low T low Testosterone Testosterone aromatase aromatase inhibition fat adipose tissue estrogen male hormones

shared by Nathan Goodyear on 29 Sep 16 - No Cached

Nathan Goodyear on 29 Sep 16

Increased fat mass equals increased aromatase estrogen production and low T.

<div class="cArrow"> </div><div class="cContentInner">Increased fat mass equals increased aromatase estrogen production and low T.</div>

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Selenomethionine and α-Tocopherol Do Not Inhibit Prostate Carcinogenesis in t... - 0 views

cancerpreventionresearch.aacrjournals.org/...371.long

prostate cancer prostate cancer estrogen estradiol male hormones

shared by Nathan Goodyear on 18 Nov 16 - No Cached

Nathan Goodyear on 18 Nov 16

In this animal study, estradiol is added to Testosterone to increase prostate carcinogenesis. Previous rat studies have shown that adding estradiol to Testosterone, which occurs naturally, increases prostate cancer risk.

<div class="cArrow"> </div><div class="cContentInner">In this animal study, estradiol is added to Testosterone to increase prostate carcinogenesis. Previous rat studies have shown that adding estradiol to Testosterone, which occurs naturally, increases prostate cancer risk. </div>

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Effect of Testosterone Replacement Therapy on Cognitive Performance and Depression in M... - 0 views

www.ncbi.nlm.nih.gov/...PMC5209560

low T Low testosterone Testosterone male hormones Testosterone therapy depression brain cognition ED erectile dysfunction

shared by Nathan Goodyear on 09 Jan 17 - No Cached

Azad et al [15] used single photon emission computed tomography and showed that, after 3~5 weeks of TRT, cerebral perfusion was increased in the midbrain and the superior frontal gyrus in seven men with hypogonadism
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After 12~14 weeks, increased perfusion was still observed in the midbrain as well as in the midcingulate gyrus
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TDS patients who received TRT showed significant improvement in cognitive function only if mild cognitive impairment was present at baseline
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...4 more annotations...
Cherrier et al [17] evaluated a sample of 32 subjects, which included 17 men with mild cognitive impairment and 15 with Alzheimer's disease. At the 6-week follow-up, patients who received TRT showed significantly better scores regarding spatial memory, constructional abilities, and verbal memory compared to those noted in the placebo group. Taken together, these results suggest that TRT has a beneficial effect on cognitive function
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TRT improved mood and well-being, and reduced fatigue and irritability in hypogonadal men
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The study by Pope et al [20] involved men with depression refractory to standard anti-depressants, and found that TRT lowered the Hamilton Depression score,
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depression tends to increase as testosterone levels decrease [21], it is highly likely that TRT improved symptoms of depression by increasing testosterone levels.
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Nathan Goodyear on 09 Jan 17

men with Testosterone <300 ng/dl with levels after 8 months of therapy achieving +680 ng/dl.

<div class="cArrow"> </div><div class="cContentInner">men with Testosterone <300 ng/dl with levels after 8 months of therapy achieving +680 ng/dl.</div>

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Testosterone Gel Supplementation for Men With Refractory Depression: A Randomized, Plac... - 0 views

ajp.psychiatryonline.org/...appi.ajp.160.1.105

depression low T low Testosterone male hormones Testosterone Testosterone therapy

shared by Nathan Goodyear on 09 Jan 17 - No Cached

Nathan Goodyear on 09 Jan 17

study that looked at men with refractory depression symptoms on depression meds with low Testosterone finds Testosterone therapy improved depression symptoms.

<div class="cArrow"> </div><div class="cContentInner">study that looked at men with refractory depression symptoms on depression meds with low Testosterone finds Testosterone therapy improved depression symptoms.</div>

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An update on the role of testosterone replacement therapy in the management of hypogona... - 0 views

www.ncbi.nlm.nih.gov/...PMC4772354

TRT testosterone replacement therapy Testosterone therapy low T low Testosterone Testosterone male hormones

shared by Nathan Goodyear on 19 Jan 17 - No Cached

Nathan Goodyear on 19 Jan 17

very nice updated review on the evidence of TRT.

<div class="cArrow"> </div><div class="cContentInner">very nice updated review on the evidence of TRT.</div>

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Relationship between Testosterone and Erectile dysfunction - 1 views

www.ncbi.nlm.nih.gov/...PMC1476110

Testosterone low T low Testosterone ED erection male hormones

shared by Nathan Goodyear on 27 Jan 17 - No Cached

Nathan Goodyear on 27 Jan 17

Though Testosterone plays a role, it's role in the erectile process is overblown.

<div class="cArrow"> </div><div class="cContentInner">Though Testosterone plays a role, it's role in the erectile process is overblown.</div>

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Prevalence and prognosis of a low serum testosterone in men with type 2 diabetes: The F... - 0 views

www.ncbi.nlm.nih.gov/...27106511

low T low Testosterone Testosterone male hormones diabetes mortality

shared by Nathan Goodyear on 26 Apr 16 - No Cached

Nathan Goodyear on 26 Apr 16

when looking at men, Testosterone levels, diabetes, and death: this study found a U shaped pattern of risk; low and high-normal total Testosterone levels were associated with increased death. No association was found with free Testosterone and SHBG.

<div class="cArrow"> </div><div class="cContentInner">when looking at men, Testosterone levels, diabetes, and death: this study found a U shaped pattern of risk; low and high-normal total Testosterone levels were associated with increased death. No association was found with free Testosterone and SHBG.</div>

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Methadone induces testosterone suppression in patients with opioid addiction : Scientif... - 0 views

www.nature.com/srep06189

methadone Testosterone male hormones

shared by Nathan Goodyear on 15 May 16 - No Cached

Nathan Goodyear on 15 May 16

Methadone suppresses Testosterone in men.

<div class="cArrow"> </div><div class="cContentInner">Methadone suppresses Testosterone in men.</div>

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Low testosterone - a risk marker rather than a risk factor for type 2 diabetes: The Jou... - 0 views

press.endocrine.org/...jc.2016-1778

low T low Testosterone Testosterone male hormones diabetes

shared by Nathan Goodyear on 13 Jun 16 - No Cached

Nathan Goodyear on 13 Jun 16

As I have been saying for awhile now, low Testosterone is the effect not the cause: new study finds that low T is a biomarker of diabetes and not a cause.

<div class="cArrow"> </div><div class="cContentInner">As I have been saying for awhile now, low Testosterone is the effect not the cause: new study finds that low T is a biomarker of diabetes and not a cause. </div>

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The effects of metformin and diet on plasma testosterone and leptin levels in obese men... - 0 views

www.ncbi.nlm.nih.gov/...11707532

metformin testosterone total testosterone free testosterone male hormones

shared by Nathan Goodyear on 04 Feb 17 - No Cached

Nathan Goodyear on 04 Feb 17

metformin caused a decrease in total and free testosterone in men

<div class="cArrow"> </div><div class="cContentInner">metformin caused a decrease in total and free testosterone in men</div>

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168024/ - 0 views

www.ncbi.nlm.nih.gov/...PMC4168024

low T low Testosterone hypogonadism Testosterone male hormones

shared by Nathan Goodyear on 08 Feb 17 - No Cached

Nathan Goodyear on 08 Feb 17

Good review of low Testosterone and treatment. The authors here recommend 400-700 ng/dl; I like 500-700 ng/dl

<div class="cArrow"> </div><div class="cContentInner">Good review of low Testosterone and treatment. The authors here recommend 400-700 ng/dl; I like 500-700 ng/dl</div>

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Estradiol in elderly men. [Aging Male. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12198740

estrogen estradiol estrone men aromatase activity hormone

shared by Nathan Goodyear on 30 Apr 12 - No Cached

Plasma levels of estradiol do not necessarily reflect tissue-level activity
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age-associated increased aromatization of testosterone
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Estradiol levels are highly significantly positively related to body fat mass and more specifically to subcutaneous abdominal fat
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Nathan Goodyear on 30 Apr 12

Review of the sources of estrogens in men and the impact it has on a man's physiology.

<div class="cArrow"> </div><div class="cContentInner">Review of the sources of estrogens in men and the impact it has on a man's physiology.</div>

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Androgen Receptor (AR) Coregulators: An Overview - 0 views

edrv.endojournals.org/...175.full

androgen receptors men male hormone

shared by Nathan Goodyear on 19 Sep 12 - No Cached

Nathan Goodyear on 19 Sep 12

Deep, but highly necessary discussion of androgen receptors.

<div class="cArrow"> </div><div class="cContentInner">Deep, but highly necessary discussion of androgen receptors.</div>

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Acute Sex Steroid Withdrawal Reduces Insulin Sensitivity in Healthy Men with Idiopathic... - 0 views

press.endocrine.org/...jc.2007-0454

Low t Testosterone insulin sensitivity resistance men male hormone inflammation glucose

shared by Nathan Goodyear on 04 Feb 14 - No Cached

Nathan Goodyear on 04 Feb 14

This study looked at a small number of men with low T. Therapy was abruptly stopped and the effects were followed. Insulin function declined. There was a trend to increased glucose and IL-6.

<div class="cArrow"> </div><div class="cContentInner">This study looked at a small number of men with low T. Therapy was abruptly stopped and the effects were followed. Insulin function declined. There was a trend to increased glucose and IL-6.</div>

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Testosterone Replacement Therapy Improves Metabolic Parameters in Hypogonadal Men with ... - 0 views

onlinelibrary.wiley.com/...full

low T Testosterone Diabetes men male hormones HgbA1c TC total cholesterol cholesterol waist circumference

shared by Nathan Goodyear on 04 Feb 14 - No Cached

Nathan Goodyear on 04 Feb 14

Testosterone therapy lowered HgbA1c in poorly controlled Diabetics. These patients were followed out to 52 weeks. Testosterone therapy, as is lifestyle change, a long term strategy of Diabetes control. Studies in controlled Diabetics have not shown a reduction in HgbA1c consistently. Total cholesterol and waist circumference were also reduced.

<div class="cArrow"> </div><div class="cContentInner">Testosterone therapy lowered HgbA1c in poorly controlled Diabetics. These patients were followed out to 52 weeks. Testosterone therapy, as is lifestyle change, a long term strategy of Diabetes control. Studies in controlled Diabetics have not shown a reduction in HgbA1c consistently. Total cholesterol and waist circumference were also reduced.</div>

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Human biological monitoring of suspected endocrine-disrupting compounds Fanib... - 0 views

www.ajandrology.com/article.asp

Xenoestrogens EDC endocrine disrupting chemicals male hormones

shared by Nathan Goodyear on 24 Feb 14 - No Cached

Nathan Goodyear on 24 Feb 14

Review of xenoestrogens and techniques for evaluation. Brief discussion of the different EDCs is included, but the majority of the study is to evaluate the different testing techniques.

<div class="cArrow"> </div><div class="cContentInner">Review of xenoestrogens and techniques for evaluation. Brief discussion of the different EDCs is included, but the majority of the study is to evaluate the different testing techniques.</div>

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Associations between serum phthalates and biomar... [Environ Int. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24583187

phthalates androgen receptors AR toxins hormones men male

shared by Nathan Goodyear on 04 Mar 14 - No Cached

Nathan Goodyear on 04 Mar 14

Phthalates have both central inhibition and peripheral effects. This article highlights the peripheral anti-androgen effects of phthalates and phthalate metabolites.

<div class="cArrow"> </div><div class="cContentInner">Phthalates have both central inhibition and peripheral effects. This article highlights the peripheral anti-androgen effects of phthalates and phthalate metabolites. </div>

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Metabolic syndrome, circulating RBP4, testosterone, and SHBG predict weight regain at 6... - 0 views

onlinelibrary.wiley.com/...abstract

metabolic syndrome metabolic syndrome low T Testosterone obesity overweight weight loss SHBG RBP4 men male hormones

shared by Nathan Goodyear on 13 Mar 14 - No Cached

Nathan Goodyear on 13 Mar 14

Interesting study finds that men with low serum Total Testosterone, elevated RBP4 and low SHBG at baseline predict weight regain. Thus Testosterone should be used as a biomarker of failure in weight loss and if low, Testosterone therapy should be employed to improved metabolic function. Other parameters, such as leptin, adiponectin, prolactin, progesterone...were not predictive.

<div class="cArrow"> </div><div class="cContentInner">Interesting study finds that men with low serum Total Testosterone, elevated RBP4 and low SHBG at baseline predict weight regain. Thus Testosterone should be used as a biomarker of failure in weight loss and if low, Testosterone therapy should be employed to improved metabolic function. Other parameters, such as leptin, adiponectin, prolactin, progesterone...were not predictive.</div>

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Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testost... - 0 views

jcem.endojournals.org/...1174.full

aromatase inhibitor Testosterone estradiol estrogen men male hormon hormoens psa

shared by Nathan Goodyear on 23 Sep 13 - No Cached

Nathan Goodyear on 23 Sep 13

Study looked at aromatase activity in androgen production in older men. The study found that aromatase inhibition with arimidex increased Testosterone production. PSA was also monitored and PSA increased in the smaller dose group versus the high dose group.

<div class="cArrow"> </div><div class="cContentInner">Study looked at aromatase activity in androgen production in older men. The study found that aromatase inhibition with arimidex increased Testosterone production. PSA was also monitored and PSA increased in the smaller dose group versus the high dose group.</div>

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